Corinne E. Fischer



Research Programs


Dr. Fischer is a staff psychiatrist with the Mental Health Service at St. Michael’s Hospital and director of Geriatric Psychiatry at St. Michael’s Hospital, Unity Health. She is an associate scientist and co-director of Neurodegenerative Research, Division of Neuroscience Research, at the Keenan Research Centre for Biomedical Science, the Li Ka Shing Knowledge Institute, St. Michael’s Hospital, Toronto, Canada. She has an academic appointment as Associate Professor at the University of Toronto in the Division of Geriatric Psychiatry and is a full member of the Institute of Medical Science where she supervises graduate students, research fellows, residents and medical students. She is an associate editor of the Journal of Alzheimer’s disease and immediate past academic co-chair of the Neuropsychiatric Symptom Professional Interest Area ISTAART in addition to being a member of several national/international organizations including CAGP, AAGP, IPA and ISTAART.  Dr. Fischer’s main clinical and research focus centres around neuropsychiatric symptoms in Alzheimer’s disease and their clinical, imaging and pathological correlates. She is a principal investigator for a number of peer-reviewed and industry sponsored grants, including a multi-centred study of photobiomodulation therapy in moderate to severe Alzheimer’s disease.

Recent Publications

  1. Fischer, CE, Churchill, N, Leggieri, M, Vuong, V, Tau, M, Fornazzari, LR et al.. Long-Known Music Exposure Effects on Brain Imaging and Cognition in Early-Stage Cognitive Decline: A Pilot Study. J Alzheimers Dis. 2021;84 (2):819-833. doi: 10.3233/JAD-210610. PubMed PMID:34602475 .
  2. Dilliott, AA, Abdelhady, A, Sunderland, KM, Farhan, SMK, Abrahao, A, Binns, MA et al.. Contribution of rare variant associations to neurodegenerative disease presentation. NPJ Genom Med. 2021;6 (1):80. doi: 10.1038/s41525-021-00243-3. PubMed PMID:34584092 PubMed Central PMC8478934.
  3. Brooks, H, Mirjalili, M, Wang, W, Kumar, S, Goodman, MS, Zomorrodi, R et al.. Assessing the Longitudinal Relationship between Theta-Gamma Coupling and Working Memory Performance in Older Adults. Cereb Cortex. 2021; :. doi: 10.1093/cercor/bhab295. PubMed PMID:34519333 .
  4. Fornazzari, L, Tan, YB, Haladyn, J, Bharatha, A, Barfett, J, Wilson-Sanchez, M et al.. The painter who changed her brain at the flick of a switch. Neurocase. 2021; :1-5. doi: 10.1080/13554794.2021.1954198. PubMed PMID:34436984 .
  5. Fornazzari, L, Fischer, CE. BIOMARKERS AND AD: WHAT WILL THE FUTURE BRING FOR "THE WORRIED WELL"?. Can J Neurol Sci. 2021; :1-4. doi: 10.1017/cjn.2021.126. PubMed PMID:34082853 .
  6. Dilliott, AA, Sunderland, KM, McLaughlin, PM, Roberts, AC, Evans, EC, Abrahao, A et al.. Association of apolipoprotein E variation with cognitive impairment across multiple neurodegenerative diagnoses. Neurobiol Aging. 2021;105 :378.e1-378.e9. doi: 10.1016/j.neurobiolaging.2021.04.011. PubMed PMID:34039480 .
  7. Weinstein, AM, Gujral, S, Butters, MA, Bowie, CR, Fischer, CE, Flint, AJ et al.. Diagnostic Precision in the Detection of Mild Cognitive Impairment: A Comparison of Two Approaches. Am J Geriatr Psychiatry. 2021; :. doi: 10.1016/j.jagp.2021.04.004. PubMed PMID:34023224 .
  8. Miller, DS, Robert, P, Ereshefsky, L, Adler, L, Bateman, D, Cummings, J et al.. Diagnostic criteria for apathy in neurocognitive disorders. Alzheimers Dement. 2021; :. doi: 10.1002/alz.12358. PubMed PMID:33949763 .
  9. Zukotynski, K, Black, SE, Kuo, PH, Bhan, A, Adamo, S, Scott, CJM et al.. Exploratory Assessment of K-means Clustering to Classify 18F-Flutemetamol Brain PET as Positive or Negative. Clin Nucl Med. 2021;46 (8):616-620. doi: 10.1097/RLU.0000000000003668. PubMed PMID:33883495 .
  10. Chandramouleeshwaran, S, Ahsan, N, Raymond, R, Nobrega, JN, Wang, W, Fischer, CE et al.. Relationships Between a New Cultured Cell-Based Serum Anticholinergic Activity Assay and Anticholinergic Burden Scales or Cognitive Performance in Older Adults. Am J Geriatr Psychiatry. 2021;29 (12):1239-1252. doi: 10.1016/j.jagp.2021.03.002. PubMed PMID:33846084 .
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Affiliations & Other Activities

  • Director of Geriatric Psychiatry, Psychiatry, St. Michael’s Hospital
  • Director of Memory Disorders Clinic, Psychiatry, St. Michael’s Hospital
  • Director of the Geriatric Mental Health Outreach Program, Psychiatry, St. Michael’s Hospital
  • Associate Professor, Department of Psychiatry, University of Toronto
  • Associate Member, IMS