Corinne E. Fischer

MD

Associate Scientist, Li Ka Shing Knowledge Institute

Research Programs

Biography

My major research focus includes the study of neuropsychiatric symptoms in dementia, specifically delusions and their neurocognitive/neurobiological correlates. I also have an interest in functional outcome studies in dementia, examining the impact of cognitive decline on real world activities such as driving, etc. As well, I have an interest in understanding how cognitive reserve (education, art, bilingualism) protects against development of dementia. Finally, I have an interest in health system issues as they apply to the elderly.

Recent Publications

  1. Brown, EE, Rashidi-Ranjbar, N, Caravaggio, F, Gerretsen, P, Pollock, BG, Mulsant, BH et al.. Brain Amyloid PET Tracer Delivery is Related to White Matter Integrity in Patients with Mild Cognitive Impairment. J Neuroimaging. 2019; :. doi: 10.1111/jon.12646. PubMed PMID:31270885 .
  2. Qian, W, Fischer, CE, Churchill, NW, Kumar, S, Rajji, T, Schweizer, TA et al.. Delusions in Alzheimer Disease are Associated With Decreased Default Mode Network Functional Connectivity. Am J Geriatr Psychiatry. 2019; :. doi: 10.1016/j.jagp.2019.03.020. PubMed PMID:31130416 .
  3. Yuen, K, Rashidi-Ranjbar, N, Verhoeff, NPLG, Kumar, S, Gallagher, D, Flint, AJ et al.. Association between Sleep Disturbances and Medial Temporal Lobe Volume in Older Adults with Mild Cognitive Impairment Free of Lifetime History of Depression. J. Alzheimers Dis. 2019;69 (2):413-421. doi: 10.3233/JAD-190160. PubMed PMID:31104028 .
  4. Hird, MA, Churchill, NW, Fischer, CE, Naglie, G, Graham, SJ, Schweizer, TA et al.. Altered Functional Brain Connectivity in Mild Cognitive Impairment during a Cognitively Complex Car Following Task. Geriatrics (Basel). 2018;3 (2):. doi: 10.3390/geriatrics3020020. PubMed PMID:31011061 PubMed Central PMC6319210.
  5. Leggieri, M, Thaut, MH, Fornazzari, L, Schweizer, TA, Barfett, J, Munoz, DG et al.. Music Intervention Approaches for Alzheimer's Disease: A Review of the Literature. Front Neurosci. 2019;13 :132. doi: 10.3389/fnins.2019.00132. PubMed PMID:30930728 PubMed Central PMC6424022.
  6. Goodman, MS, Zomorrodi, R, Kumar, S, Barr, MS, Daskalakis, ZJ, Blumberger, DM et al.. Changes in Theta but not Alpha Modulation Are Associated with Impairment in Working Memory in Alzheimer's Disease and Mild Cognitive Impairment. J. Alzheimers Dis. 2019;68 (3):1085-1094. doi: 10.3233/JAD-181195. PubMed PMID:30909240 .
  7. Talwar, NA, Churchill, NW, Hird, MA, Pshonyak, I, Tam, F, Fischer, CE et al.. The Neural Correlates of the Clock-Drawing Test in Healthy Aging. Front Hum Neurosci. 2019;13 :25. doi: 10.3389/fnhum.2019.00025. PubMed PMID:30804769 PubMed Central PMC6370722.
  8. Fischer, CE, Kortebi, I, Karameh, WK, Kumar, S, Gallagher, D, Golas, A et al.. Examining the Link Between Cardiovascular Risk Factors and Neuropsychiatric Symptoms in Mild Cognitive Impairment and Major Depressive Disorder in Remission. J. Alzheimers Dis. 2019;67 (4):1305-1311. doi: 10.3233/JAD-181099. PubMed PMID:30741676 .
  9. Koo, KYG, Schweizer, TA, Fischer, CE, Munoz, DG. Abnormal Sleep Behaviours Across the Spectrum of Alzheimer's Disease Severity: Influence of APOE Genotypes and Lewy Bodies. Curr Alzheimer Res. 2019;16 (3):243-250. doi: 10.2174/1567205016666190103161034. PubMed PMID:30605058 PubMed Central PMC6613208.
  10. Freedman, M, Leach, L, Carmela Tartaglia, M, Stokes, KA, Goldberg, Y, Spring, R et al.. Correction to: The Toronto cognitive assessment (TorCA): normative data and validation to detect amnestic mild cognitive impairment. Alzheimers Res Ther. 2018;10 (1):120. doi: 10.1186/s13195-018-0446-z. PubMed PMID:30526675 PubMed Central PMC6286597.
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Affiliations & Other Activities

  • Director of Geriatric Psychiatry, Psychiatry, St. Michael’s Hospital
  • Director of Memory Disorders Clinic, Psychiatry, St. Michael’s Hospital
  • Director of the Geriatric Mental Health Outreach Program, Psychiatry, St. Michael’s Hospital
  • Associate Professor, Department of Psychiatry, University of Toronto
  • Associate Member, IMS
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