Corinne E. Fischer

MD

Associate Scientist, Li Ka Shing Knowledge Institute

Research Programs

Biography

My major research focus includes the study of neuropsychiatric symptoms in dementia, specifically delusions and their neurocognitive/neurobiological correlates. I also have an interest in functional outcome studies in dementia, examining the impact of cognitive decline on real world activities such as driving, etc. As well, I have an interest in understanding how cognitive reserve (education, art, bilingualism) protects against development of dementia. Finally, I have an interest in health system issues as they apply to the elderly.

Recent Publications

  1. Freedman, M, Leach, L, Carmela Tartaglia, M, Stokes, KA, Goldberg, Y, Spring, R et al.. The Toronto Cognitive Assessment (TorCA): normative data and validation to detect amnestic mild cognitive impairment. Alzheimers Res Ther. 2018;10 (1):65. doi: 10.1186/s13195-018-0382-y. PubMed PMID:30021658 PubMed Central PMC6052695.
  2. Fornazzari, L, Leggieri, M, Schweizer, TA, Arizaga, RL, Allegri, RF, Fischer, CE et al.. Hyper memory, synaesthesia, savants Luria and Borges revisited. Dement Neuropsychol. ;12 (2):101-104. doi: 10.1590/1980-57642018dn12-020001. PubMed PMID:29988344 PubMed Central PMC6022980.
  3. Kim, J, Schweizer, TA, Fischer, CE, Munoz, DG. Psychosis in "Cognitively Asymptomatic" Elderly Subjects is Associated With Neuritic Plaque Load, Not Neurofibrillary Tangles. Alzheimer Dis Assoc Disord. ;32 (3):185-189. doi: 10.1097/WAD.0000000000000250. PubMed PMID:29553944 PubMed Central PMC6107422.
  4. Karimpoor, M, Churchill, NW, Tam, F, Fischer, CE, Schweizer, TA, Graham, SJ et al.. Functional MRI of Handwriting Tasks: A Study of Healthy Young Adults Interacting with a Novel Touch-Sensitive Tablet. Front Hum Neurosci. 2018;12 :30. doi: 10.3389/fnhum.2018.00030. PubMed PMID:29487511 PubMed Central PMC5816817.
  5. Karimpoor, M, Churchill, NW, Tam, F, Fischer, CE, Schweizer, TA, Graham, SJ et al.. Tablet-Based Functional MRI of the Trail Making Test: Effect of Tablet Interaction Mode. Front Hum Neurosci. 2017;11 :496. doi: 10.3389/fnhum.2017.00496. PubMed PMID:29114212 PubMed Central PMC5660710.
  6. Fischer, CE, Qian, W, Schweizer, TA, Ismail, Z, Smith, EE, Millikin, CP et al.. Determining the impact of psychosis on rates of false-positive and false-negative diagnosis in Alzheimer's disease. Alzheimers Dement (N Y). 2017;3 (3):385-392. doi: 10.1016/j.trci.2017.06.001. PubMed PMID:29067344 PubMed Central PMC5651446.
  7. Qian, W, Fischer, CE, Schweizer, TA, Munoz, DG. Association Between Psychosis Phenotype and APOE Genotype on the Clinical Profiles of Alzheimer's Disease. Curr Alzheimer Res. 2018;15 (2):187-194. doi: 10.2174/1567205014666170829114346. PubMed PMID:28847281 PubMed Central PMC6211852.
  8. Fischer, CE, Agüera-Ortiz, L. Psychosis and dementia: risk factor, prodrome, or cause?. Int Psychogeriatr. 2018;30 (2):209-219. doi: 10.1017/S1041610217000874. PubMed PMID:28560931 .
  9. Fornazzari, L, Mansur, A, Acuna, KO, Schweizer, TA, Fischer, CE. Always in Tune: The Unforgettable Memory for Music in Alzheimer's Disease. Can J Neurol Sci. 2017;44 (2):209-211. doi: 10.1017/cjn.2016.436. PubMed PMID:28231865 .
  10. Kim, J, Fischer, CE, Schweizer, TA, Munoz, DG. Gender and Pathology-Specific Effect of Apolipoprotein E Genotype on Psychosis in Alzheimer's Disease. Curr Alzheimer Res. 2017;14 (8):834-840. doi: 10.2174/1567205014666170220150021. PubMed PMID:28219318 PubMed Central PMC5837801.
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Affiliations & Other Activities

  • Director of Geriatric Psychiatry, Psychiatry, St. Michael’s Hospital
  • Director of Memory Disorders Clinic, Psychiatry, St. Michael’s Hospital
  • Director of the Geriatric Mental Health Outreach Program, Psychiatry, St. Michael’s Hospital
  • Associate Professor, Department of Psychiatry, University of Toronto
  • Associate Member, IMS
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