Corinne E. Fischer



Research Programs


My major research focus includes the study of neuropsychiatric symptoms in dementia, specifically delusions and their neurocognitive/neurobiological correlates. I also have an interest in functional outcome studies in dementia, examining the impact of cognitive decline on real world activities such as driving, etc. As well, I have an interest in understanding how cognitive reserve (education, art, bilingualism) protects against development of dementia. Finally, I have an interest in health system issues as they apply to the elderly.

Recent Publications

  1. Chandramouleeshwaran, S, Ahsan, N, Raymond, R, Nobrega, JN, Wang, W, Fischer, CE et al.. Relationships Between a New Cultured Cell-Based Serum Anticholinergic Activity Assay and Anticholinergic Burden Scales or Cognitive Performance in Older Adults. Am J Geriatr Psychiatry. 2021; :. doi: 10.1016/j.jagp.2021.03.002. PubMed PMID:33846084 .
  2. Diniz, BS, Vieira, EM, Mendes-Silva, AP, Bowie, CR, Butters, MA, Fischer, CE et al.. Mild cognitive impairment and major depressive disorder are associated with molecular senescence abnormalities in older adults. Alzheimers Dement (N Y). 2021;7 (1):e12129. doi: 10.1002/trc2.12129. PubMed PMID:33816758 PubMed Central PMC8012242.
  3. Karameh, WK, Kortebi, I, Kumar, S, Gallagher, D, Golas, A, Lanctôt, KL et al.. Comparing cardiovascular risk factors in older persons with mild cognitive impairment and lifetime history of major depressive disorder. Int Psychogeriatr. 2021; :1-7. doi: 10.1017/S1041610221000259. PubMed PMID:33775259 .
  4. Tang-Wai, DF, Smith, EE, Bruneau, MA, Burhan, AM, Chatterjee, A, Chertkow, H et al.. CCCDTD5 recommendations on early and timely assessment of neurocognitive disorders using cognitive, behavioral, and functional scales. Alzheimers Dement (N Y). 2020;6 (1):e12057. doi: 10.1002/trc2.12057. PubMed PMID:33209972 PubMed Central PMC7657153.
  5. Kumar, S, Zomorrodi, R, Ghazala, Z, Goodman, MS, Blumberger, DM, Daskalakis, ZJ et al.. Effects of repetitive paired associative stimulation on brain plasticity and working memory in Alzheimer's disease: a pilot randomized double-blind-controlled trial. Int Psychogeriatr. 2020; :1-13. doi: 10.1017/S1041610220003518. PubMed PMID:33190659 .
  6. Mundluru, J, Subhan, A, Lo, TWB, Churchill, N, Fornazzari, L, Munoz, DG et al.. Neuropsychiatric Presentations due to Traumatic Brain Injury in Cognitively Normal Older Adults. J Neurotrauma. 2021;38 (5):566-572. doi: 10.1089/neu.2020.7282. PubMed PMID:32977734 PubMed Central PMC8020506.
  7. Cummings, J, Pinto, LC, Cruz, M, Fischer, CE, Gerritsen, DL, Grossberg, GT et al.. Criteria for Psychosis in Major and Mild Neurocognitive Disorders: International Psychogeriatric Association (IPA) Consensus Clinical and Research Definition. Am J Geriatr Psychiatry. 2020;28 (12):1256-1269. doi: 10.1016/j.jagp.2020.09.002. PubMed PMID:32958332 PubMed Central PMC7669601.
  8. Brooks, H, Goodman, MS, Bowie, CR, Zomorrodi, R, Blumberger, DM, Butters, MA et al.. Theta-gamma coupling and ordering information: a stable brain-behavior relationship across cognitive tasks and clinical conditions. Neuropsychopharmacology. 2020;45 (12):2038-2047. doi: 10.1038/s41386-020-0759-z. PubMed PMID:32682324 PubMed Central PMC7547084.
  9. Rajji, TK, Bowie, CR, Herrmann, N, Pollock, BG, Bikson, M, Blumberger, DM et al.. Design and Rationale of the PACt-MD Randomized Clinical Trial: Prevention of Alzheimer's dementia with Cognitive remediation plus transcranial direct current stimulation in Mild cognitive impairment and Depression. J Alzheimers Dis. 2020;76 (2):733-751. doi: 10.3233/JAD-200141. PubMed PMID:32568198 .
  10. Rashidi-Ranjbar, N, Rajji, TK, Kumar, S, Herrmann, N, Mah, L, Flint, AJ et al.. Frontal-executive and corticolimbic structural brain circuitry in older people with remitted depression, mild cognitive impairment, Alzheimer's dementia, and normal cognition. Neuropsychopharmacology. 2020;45 (9):1567-1578. doi: 10.1038/s41386-020-0715-y. PubMed PMID:32422643 PubMed Central PMC7360554.
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Affiliations & Other Activities

  • Director of Geriatric Psychiatry, Psychiatry, St. Michael’s Hospital
  • Director of Memory Disorders Clinic, Psychiatry, St. Michael’s Hospital
  • Director of the Geriatric Mental Health Outreach Program, Psychiatry, St. Michael’s Hospital
  • Associate Professor, Department of Psychiatry, University of Toronto
  • Associate Member, IMS