David Munoz


Project Investigator, Keenan Research Centre for Biomedical Science

Research Programs


Dr. David Munoz holds an MD from Navarre and MSc in Pathology from Queen’s University, Ontario. He trained in neurology and neuropathology and became a Fellow of the Royal College of Physicians and Surgeons of Canada in 1984. He has practiced in Vermont, Saskatoon, London (ON), Madrid, and Toronto, and briefly in Vancouver. He is currently a Neuropathologist and Head, Division of Pathology at St. Michael’s Hospital, Toronto, and Professor, Department of Laboratory Medicine and Pathobiology, University of Toronto. He is the author of 194 peer-reviewed papers, 20 book chapters, and co-author of one book. He has held research grants in Canada (Medical Research Council and Canadian Institutes of Health Reasearch) and USA (National Institutes of Health).

His research interest is focused on neuropathology, particularly the mechanisms of development and progression of degenerative diseases of the brain, including Alzheimer’s disease, the non-Alzheimer dementias, movement disorders, and amyotrophic lateral sclerosis. His other research interest in neurooncology is derived from his clinical practice.

Please note: Dr. D. Munoz is not taking any summer students in 2018.

Recent Publications

  1. Fischer, CE, Kortebi, I, Karameh, WK, Kumar, S, Gallagher, D, Golas, A et al.. Examining the Link Between Cardiovascular Risk Factors and Neuropsychiatric Symptoms in Mild Cognitive Impairment and Major Depressive Disorder in Remission. J. Alzheimers Dis. 2019; :. doi: 10.3233/JAD-181099. PubMed PMID:30741676 .
  2. Huang, RY, Bi, WL, Griffith, B, Kaufmann, TJ, la Fougère, C, Schmidt, NO et al.. Imaging and diagnostic advances for intracranial meningiomas. Neuro-oncology. 2019;21 (Supplement_1):i44-i61. doi: 10.1093/neuonc/noy143. PubMed PMID:30649491 PubMed Central PMC6347083.
  3. Suppiah, S, Nassiri, F, Bi, WL, Dunn, IF, Hanemann, CO, Horbinski, CM et al.. Molecular and translational advances in meningiomas. Neuro-oncology. 2019;21 (Supplement_1):i4-i17. doi: 10.1093/neuonc/noy178. PubMed PMID:30649490 PubMed Central PMC6347079.
  4. Brastianos, PK, Galanis, E, Butowski, N, Chan, JW, Dunn, IF, Goldbrunner, R et al.. Advances in multidisciplinary therapy for meningiomas. Neuro-oncology. 2019;21 (Supplement_1):i18-i31. doi: 10.1093/neuonc/noy136. PubMed PMID:30649489 PubMed Central PMC6347080.
  5. Nassiri, F, Price, B, Shehab, A, Au, K, Cusimano, MD, Jenkinson, MD et al.. Life after surgical resection of a meningioma: a prospective cross-sectional study evaluating health-related quality of life. Neuro-oncology. 2019;21 (Supplement_1):i32-i43. doi: 10.1093/neuonc/noy152. PubMed PMID:30649488 PubMed Central PMC6347082.
  6. Koo, HKYG, Schweizer, TA, Fischer, CE, Munoz, DG. Abnormal Sleep Behaviours Across the Spectrum of Alzheimer's Disease Severity: Influence of APOE Genotypes and Lewy Bodies. Curr Alzheimer Res. 2019; :. doi: 10.2174/1567205016666190103161034. PubMed PMID:30605058 .
  7. Karameh, WK, Murari, G, Schweizer, TA, Munoz, DG, Fischer, CE. Psychosis in neurodegenerative disorders: recent developments. Curr Opin Psychiatry. 2019;32 (2):117-122. doi: 10.1097/YCO.0000000000000476. PubMed PMID:30520740 .
  8. Qian, W, Schweizer, TA, Churchill, NW, Millikin, C, Ismail, Z, Smith, EE et al.. Gray Matter Changes Associated With the Development of Delusions in Alzheimer Disease. Am J Geriatr Psychiatry. 2018; :. doi: 10.1016/j.jagp.2018.09.016. PubMed PMID:30503703 .
  9. Goulam-Houssein, S, Grenville, JL, Mastrocostas, K, Munoz, DG, Lin, A, Bharatha, A et al.. IgG4-related intracranial disease. Neuroradiol J. 2019;32 (1):29-35. doi: 10.1177/1971400918806323. PubMed PMID:30320530 PubMed Central PMC6327361.
  10. Beach, TG, Serrano, GE, Kremer, T, Canamero, M, Dziadek, S, Sade, H et al.. Immunohistochemical Method and Histopathology Judging for the Systemic Synuclein Sampling Study (S4). J. Neuropathol. Exp. Neurol. 2018;77 (9):793-802. doi: 10.1093/jnen/nly056. PubMed PMID:30107604 PubMed Central PMC6097838.
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Affiliations & Other Activities

  • Head, Division of Pathology, St. Michael’s Hospital
  • Professor, Laboratory Medicine and Pathobiology, University of Toronto