Dr. Yousef is an anatomical pathologist and the division head of Molecular Diagnostics at St. Michael’s Hospital. He is a Professor at the University of Toronto and a Full Scientist at the Li Ka Shing Knowledge Institute of St. Michael’s Hospital. He is also the director of postgraduate research of the Department of Laboratory Medicine and Pathobiology and the director of the CELIC Centre for molecular innovation at St. Michael’s Hospital.
His research laboratory is one of the leading laboratories focusing on the cancer biomarkers in renal cell carcinoma and prostate cancer using an integrated genomic, quantitative proteomic, transcriptomic and miRNA approaches with extensive bioinformatics analysis. His laboratory is also internationally recognized in miRNA research. In addition, he also published extensively about the discovery of kallikrein family of tumor markers and their roles as cancer biomarkers.
Dr. Yousef is a founding member of the International Scientific Committee of Kallikreins and was the chair of the 5th international symposium on Kallikreins in 2013. He is also the Vice President of the International Society of Enzymology.
He has over 200 published research papers and review articles and 15 book chapters. He is the editor-in-Chief of the Canadian Journal of Pathology and serves as a reviewer for over 40 journals. He is also the editor of a book on “Molecular Pathology in Cancer”. He serves as a reviewer for many national and international granting agencies.
He has served on numerous academic and governmental advisory committees, including the international kallikrein nomenclature Committee and the International Society of Urologic Pathology Kidney Cancer Classification in 2012. He is also a co-leader of the Kidney Cancer Research Network of Canada personalized medicine initiative; and member of the steering committee for prostate cancer management in Ontario.
At the pathology education frontier, he is a member of the Royal College Examination Board in Anatomical pathology and is leading the committee to digitalize the Royal College exam in Pathology. He is also a founding member and Chair of Pathology Informatics at the Canadian Association of Pathologists; His research was recognized by prestigious awards from the Royal College of Physicians, Canadian Association of Pathologists, and the United States National Academy of Clinical Chemistry.