My basic/bench research activities involve the use of a canine model of rapid pacing to study mechanisms of progression of heart failure. My clinical research activities involve the assessment of ultrafiltration and the use of biomarker including B-type natriuretic peptide and new biomarkers in the management of acute and chronic heart failure, as well as the quality of care in heart failure. I am also interested in the assessment of the interaction of ethnicity with cardiovascular disease.