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Howard Berger

MD

Investigator

Email: Howard.Berger@unityhealth.to
Tel: 416-864-6060 ext. 8408

Biography

Our research focuses on methods of screening for gestational diabetes and the impact of visceral adiposity in pregnancy on glycemia and perinatal outcomes. A second research collaboration exists with the Motherisk Unit at The Hospital for Sick Children. We have established a lacental perfusion lab at St. Michael’s Hospital and utilize it to study the placental transport of medications and drugs in a well validated in vitro model.

 

Recent Publications

  1. Pinto, L, Bapat, P, de Lima Moreira, F, Lubetsky, A, de Carvalho Cavalli, R, Berger, H et al.. Chiral Transplacental Pharmacokinetics of Fexofenadine: Impact of P-Glycoprotein Inhibitor Fluoxetine Using the Human Placental Perfusion Model. Pharm Res. 2021; :. doi: 10.1007/s11095-021-03035-7. PubMed PMID:33825113 .
  2. Ashwal, E, Hiersch, L, Berger, H, Aviram, A, Zaltz, A, Kingdom, J et al.. Pathologic Basis for the Definition of Discordant Growth in Dichorionic Twins. Fetal Diagn Ther. 2021; :1-9. doi: 10.1159/000514328. PubMed PMID:33780952 .
  3. Read, SH, Rosella, LC, Berger, H, Feig, DS, Fleming, K, Kaul, P et al.. Diabetes after pregnancy: a study protocol for the derivation and validation of a risk prediction model for 5-year risk of diabetes following pregnancy. Diagn Progn Res. 2021;5 (1):5. doi: 10.1186/s41512-021-00095-6. PubMed PMID:33678196 PubMed Central PMC7938478.
  4. Dennis, CL, Marini, F, Dick, JA, Atkinson, S, Barrett, J, Bell, R et al.. Protocol for a randomised trial evaluating a preconception-early childhood telephone-based intervention with tailored e-health resources for women and their partners to optimise growth and development among children in Canada: a Healthy Life Trajectory Initiative (HeLTI Canada). BMJ Open. 2021;11 (2):e046311. doi: 10.1136/bmjopen-2020-046311. PubMed PMID:33568380 PubMed Central PMC7878148.
  5. Read, SH, Rosella, LC, Berger, H, Feig, DS, Fleming, K, Ray, JG et al.. BMI and risk of gestational diabetes among women of South Asian and Chinese ethnicity: a population-based study. Diabetologia. 2021;64 (4):805-813. doi: 10.1007/s00125-020-05356-5. PubMed PMID:33486538 .
  6. Davidson, AJF, Park, AL, Berger, H, Aoyama, K, Harel, Z, Cohen, E et al.. Association of Improved Periconception Hemoglobin A1c With Pregnancy Outcomes in Women With Diabetes. JAMA Netw Open. 2020;3 (12):e2030207. doi: 10.1001/jamanetworkopen.2020.30207. PubMed PMID:33355674 PubMed Central PMC7758806.
  7. Yusuf Ibrahim, A, Park, AL, Berger, H, Ray, JG. Maternal Visceral Adipose Tissue and Risk of Having a Small or Large for Gestational Age Infant. J Obstet Gynaecol Can. 2020; :. doi: 10.1016/j.jogc.2020.11.019. PubMed PMID:33333315 .
  8. Feig, DS, Donovan, LE, Zinman, B, Sanchez, JJ, Asztalos, E, Ryan, EA et al.. Metformin in women with type 2 diabetes in pregnancy (MiTy): a multicentre, international, randomised, placebo-controlled trial. Lancet Diabetes Endocrinol. 2020;8 (10):834-844. doi: 10.1016/S2213-8587(20)30310-7. PubMed PMID:32946820 .
  9. Ashwal, E, Fan, IY, Berger, H, Livne, MY, Hiersch, L, Aviram, A et al.. The association between fetal head station at the first diagnosis of the second stage of labor and delivery outcomes. Am J Obstet Gynecol. 2021;224 (3):306.e1-306.e8. doi: 10.1016/j.ajog.2020.09.006. PubMed PMID:32926858 .
  10. Peterson, W, Liederman, Z, Baker, J, Floros, G, Martin, R, Berger, H et al.. Hemorrhagic, thrombotic and obstetric complications of congenital dysfibrinogenemia in a previously asymptomatic woman. Thromb Res. 2020;196 :127-129. doi: 10.1016/j.thromres.2020.08.028. PubMed PMID:32866823 .
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Affiliations & Other Activities

  • Head, Maternal Fetal Medicine and Obstetric Ultrasound, Obstetrics and Gynecology, St. Michael’s Hospital
  • Deputy Chief, Obstetrics, St. Michael’s Hospital
  • Program Director: Advanced High Risk Obstetrics, Obstetrics and Gynecology, St. Michael’s Hospital and University of Toronto
  • Associate Professor, Department of Obstetrics and Gynecology, University of Toronto
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