Howard Leong-Poi




Dr. Howard Leong-Poi is a Clinician Scientist in the Keenan Research Centre for Biomedical Science and Head of the Division of Cardiology at St. Michael’s Hospital. He is also an Associate Professor of Medicine at the University of Toronto. He is the current incumbent of the Brazilian Ball Chair in Cardiology at St. Michael’s Hospital. His research has been funded by the Canadian Institutes for Health Research (CIHR), Heart and Stroke Foundation of Canada (HSFC) and the Canadian Foundation for Innovation. He has held personnel support from the CIHR (New Investigator), HSFC (Clinician Scientist – Phase II Award) and the Ministry of Research and Innovation (Early Researcher Award). He has published over 100 articles in peer-reviewed journals, and serves on the editorial board of the Canadian Journal of Cardiology. Dr. Leong-Poi has served on numerous grant review panels, including the Canadian Institutes of Health Research (CIHR) Cardiovascular B (CSB) – Chair 2012-2015, and Heart & Stroke Foundation of Canada (Committees I and II). His basic biomedical research focuses on ultrasound-targeted gene- and cell-based therapies for cardiovascular disease and cancer. His clinical research interests revolve around cardiac imaging, predominantly echocardiography, in ischemic heart disease, heart failure and valvular heart disease.

Recent Publications

  1. Hibino, M, Dhingra, NK, Verma, S, Chan, V, Quan, A, Gregory, AJ et al.. Mitral repair with leaflet preservation versus leaflet resection and ventricular reverse remodeling from a randomized trial. J Thorac Cardiovasc Surg. 2021; :. doi: 10.1016/j.jtcvs.2021.08.081. PubMed PMID:34702564 .
  2. Meagher, P, Civitarese, R, Lee, X, Gordon, M, Bugyei-Twum, A, Desjardins, JF et al.. The Goto Kakizaki rat: Impact of age upon changes in cardiac and renal structure, function. PLoS One. 2021;16 (6):e0252711. doi: 10.1371/journal.pone.0252711. PubMed PMID:34166385 PubMed Central PMC8224913.
  3. Roifman, I, Arora, RC, Bewick, D, Chow, CM, Clarke, B, Cowan, S et al.. Cardiovascular Care Delivery During the Second Wave of COVID-19 in Canada. Can J Cardiol. 2021;37 (5):790-793. doi: 10.1016/j.cjca.2020.11.016. PubMed PMID:33307163 PubMed Central PMC7836859.
  4. Sanfilippo, AJ, Kolos, A, Chan, K, Leong-Poi, H, Sasson, Z, Wald, R et al.. Impact of a Mandated Accreditation Process on 1,045 Registered Echocardiographic Service Providers in a Previously Unregulated, Publicly Funded Environment. J Am Soc Echocardiogr. 2021;34 (3):308-315. doi: 10.1016/j.echo.2020.09.018. PubMed PMID:33191003 .
  5. Chan, V, Mazer, CD, Ali, FM, Quan, A, Ruel, M, de Varennes, BE et al.. Randomized, Controlled Trial Comparing Mitral Valve Repair With Leaflet Resection Versus Leaflet Preservation on Functional Mitral Stenosis: The CAMRA CardioLink-2 Study. Circulation. 2020;142 (14):1342-1350. doi: 10.1161/CIRCULATIONAHA.120.046853. PubMed PMID:33017212 .
  6. Moulson, N, Bewick, D, Selway, T, Harris, J, Suskin, N, Oh, P et al.. Cardiac Rehabilitation During the COVID-19 Era: Guidance on Implementing Virtual Care. Can J Cardiol. 2020;36 (8):1317-1321. doi: 10.1016/j.cjca.2020.06.006. PubMed PMID:32553606 PubMed Central PMC7293761.
  7. Virani, A, Singh, G, Bewick, D, Chow, CM, Clarke, B, Cowan, S et al.. Guiding Cardiac Care During the COVID-19 Pandemic: How Ethics Shapes Our Health System Response. Can J Cardiol. 2020;36 (8):1313-1316. doi: 10.1016/j.cjca.2020.06.002. PubMed PMID:32505633 PubMed Central PMC7270812.
  8. Turgeon, RD, Zieroth, S, Bewick, D, Chow, CM, Clarke, B, Cowan, S et al.. Use of Renin-Angiotensin System Blockers During the COVID-19 Pandemic: Early Guidance and Evolving Evidence. Can J Cardiol. 2020;36 (8):1180-1182. doi: 10.1016/j.cjca.2020.05.033. PubMed PMID:32502522 PubMed Central PMC7265831.
  9. Bami, K, Gandhi, S, Leong-Poi, H, Yan, AT, Ho, E, Zahrani, M et al.. Effects of Empagliflozin on Left Ventricular Remodeling in Patients with Type 2 Diabetes and Coronary Artery Disease: Echocardiographic Substudy of the EMPA-HEART CardioLink-6 Randomized Clinical Trial. J Am Soc Echocardiogr. 2020;33 (5):644-646. doi: 10.1016/j.echo.2020.02.005. PubMed PMID:32199780 .
  10. Angaran, P, Dorian, P, Ha, ACT, Thavendiranathan, P, Tsang, W, Leong-Poi, H et al.. Association of Left Ventricular Ejection Fraction with Mortality and Hospitalizations. J Am Soc Echocardiogr. 2020;33 (7):802-811.e6. doi: 10.1016/j.echo.2019.12.016. PubMed PMID:32164977 .
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Affiliations & Other Activities

  • Chair, The Brazilian Ball Chair in Cardiology Research, St. Michael’s Hospital
  • Head, Division of Cardiology, St. Michael’s Hospital
  • Associate Professor of Medicine, Medicine/Cardiology, St. Michael’s Hospital
  • Adjunct Scientist, Ryerson University