Kamel Kamel

FRCP(C), MB BCh

Associate Scientist, Li Ka Shing Knowledge Institute

Biography

Research Interests

Dysnatremias, dyskalemias, metabolic acidosis, metabolic alkalosis, nephrolithiasis

Research Activities

1. Clinical disorders of fluid and electrolytes and acid-base balance
2. Metabolic regulation and acid-base balance
3. Pathophysiology of nephrolithiasis

Recent Publications

  1. Kamel, KS, Chin, PK, Doogue, MP, Barclay, ML. Comment on: "Effect of Age and Renal Function on Idarucizumab Pharmacokinetics and Idarucizumab-Mediated Reversal of Dabigatran Anticoagulant Activity in a Randomized, Double-Blind, Crossover Phase Ib Study". Clin Pharmacokinet. 2017;56 (2):207-208. doi: 10.1007/s40262-016-0481-5. PubMed PMID:28035591 .
  2. Kamel, KS, Schreiber, M, Carlotti, AP, Halperin, ML. Approach to the Treatment of Diabetic Ketoacidosis. Am. J. Kidney Dis. 2016;68 (6):967-972. doi: 10.1053/j.ajkd.2016.05.034. PubMed PMID:27599629 .
  3. Harel, Z, Kamel, KS. Optimal Dose and Method of Administration of Intravenous Insulin in the Management of Emergency Hyperkalemia: A Systematic Review. PLoS ONE. 2016;11 (5):e0154963. doi: 10.1371/journal.pone.0154963. PubMed PMID:27148740 PubMed Central PMC4857926.
  4. Kamel, KS, Halperin, ML. Acid-base problems in diabetic ketoacidosis. N. Engl. J. Med. 2015;372 (20):1969-70. doi: 10.1056/NEJMc1502745. PubMed PMID:25970063 .
  5. Kamel, KS, Halperin, ML. Acid-base problems in diabetic ketoacidosis. N. Engl. J. Med. 2015;372 (6):546-54. doi: 10.1056/NEJMra1207788. PubMed PMID:25651248 .
  6. Kamel, KS, Schreiber, M, Halperin, ML. Integration of the response to a dietary potassium load: a paleolithic perspective. Nephrol. Dial. Transplant. 2014;29 (5):982-9. doi: 10.1093/ndt/gft499. PubMed PMID:24789504 .
  7. Kim, N, Cheema-Dhadli, S, Hare, GM, Chong, CK, Halperin, ML, Kamel, KS et al.. Non-natriuretic doses of furosemide: potential use for decreasing the workload of the renal outer medulla with minimal magnesium wasting in the rat. Nephron Physiol. 2012;122 (1-2):7-12. doi: 10.1159/000346741. PubMed PMID:23548701 .
  8. Kamel, KS, Schreiber, M. Asking the question again: are cation exchange resins effective for the treatment of hyperkalemia?. Nephrol. Dial. Transplant. 2012;27 (12):4294-7. doi: 10.1093/ndt/gfs293. PubMed PMID:22989741 .
  9. Cheema-Dhadli, S, Chong, CK, Kamel, KS, Halperin, ML. An acute infusion of lactic acid lowers the concentration of potassium in arterial plasma by inducing a shift of potassium into cells of the liver in fed rats. Nephron Physiol. 2012;120 (2):p7-15. doi: 10.1159/000336321. PubMed PMID:22555123 .
  10. Kamel, KS, Halperin, ML. The importance of distal delivery of filtrate and residual water permeability in the pathophysiology of hyponatremia. Nephrol. Dial. Transplant. 2012;27 (3):872-5. doi: 10.1093/ndt/gfr790. PubMed PMID:22379181 .
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Affiliations & Other Activities

  • Division of Nephrology, St. Michael’s Hospital
  • Professor, Medicine, University of Toronto
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