Kamel Kamel


Associate Scientist, Li Ka Shing Knowledge Institute


Research Interests

Dysnatremias, dyskalemias, metabolic acidosis, metabolic alkalosis, nephrolithiasis

Research Activities

1. Clinical disorders of fluid and electrolytes and acid-base balance
2. Metabolic regulation and acid-base balance
3. Pathophysiology of nephrolithiasis

Recent Publications

  1. Kamel, KS, Chin, PK, Doogue, MP, Barclay, ML. Comment on: "Effect of Age and Renal Function on Idarucizumab Pharmacokinetics and Idarucizumab-Mediated Reversal of Dabigatran Anticoagulant Activity in a Randomized, Double-Blind, Crossover Phase Ib Study". Clin Pharmacokinet. 2017;56 (2):207-208. doi: 10.1007/s40262-016-0481-5. PubMed PMID:28035591 .
  2. Kamel, KS, Schreiber, M, Carlotti, AP, Halperin, ML. Approach to the Treatment of Diabetic Ketoacidosis. Am. J. Kidney Dis. 2016;68 (6):967-972. doi: 10.1053/j.ajkd.2016.05.034. PubMed PMID:27599629 .
  3. Harel, Z, Kamel, KS. Optimal Dose and Method of Administration of Intravenous Insulin in the Management of Emergency Hyperkalemia: A Systematic Review. PLoS ONE. 2016;11 (5):e0154963. doi: 10.1371/journal.pone.0154963. PubMed PMID:27148740 PubMed Central PMC4857926.
  4. Kamel, KS, Halperin, ML. Acid-base problems in diabetic ketoacidosis. N. Engl. J. Med. 2015;372 (20):1969-70. doi: 10.1056/NEJMc1502745. PubMed PMID:25970063 .
  5. Kamel, KS, Halperin, ML. Acid-base problems in diabetic ketoacidosis. N. Engl. J. Med. 2015;372 (6):546-54. doi: 10.1056/NEJMra1207788. PubMed PMID:25651248 .
  6. Kamel, KS, Schreiber, M, Halperin, ML. Integration of the response to a dietary potassium load: a paleolithic perspective. Nephrol. Dial. Transplant. 2014;29 (5):982-9. doi: 10.1093/ndt/gft499. PubMed PMID:24789504 .
  7. Kim, N, Cheema-Dhadli, S, Hare, GM, Chong, CK, Halperin, ML, Kamel, KS et al.. Non-natriuretic doses of furosemide: potential use for decreasing the workload of the renal outer medulla with minimal magnesium wasting in the rat. Nephron Physiol. 2012;122 (1-2):7-12. doi: 10.1159/000346741. PubMed PMID:23548701 .
  8. Kamel, KS, Schreiber, M. Asking the question again: are cation exchange resins effective for the treatment of hyperkalemia?. Nephrol. Dial. Transplant. 2012;27 (12):4294-7. doi: 10.1093/ndt/gfs293. PubMed PMID:22989741 .
  9. Cheema-Dhadli, S, Chong, CK, Kamel, KS, Halperin, ML. An acute infusion of lactic acid lowers the concentration of potassium in arterial plasma by inducing a shift of potassium into cells of the liver in fed rats. Nephron Physiol. 2012;120 (2):p7-15. doi: 10.1159/000336321. PubMed PMID:22555123 .
  10. Kamel, KS, Halperin, ML. The importance of distal delivery of filtrate and residual water permeability in the pathophysiology of hyponatremia. Nephrol. Dial. Transplant. 2012;27 (3):872-5. doi: 10.1093/ndt/gfr790. PubMed PMID:22379181 .
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Affiliations & Other Activities

  • Division of Nephrology, St. Michael’s Hospital
  • Professor, Medicine, University of Toronto