Karen Cross


Associate Scientist, Keenan Research Centre for Biomedical Science

Research Programs


Karen Cross Lab ❯


Dr. Karen Cross is a Plastic, Reconstructive and Aesthetic Surgeon and a Surgeon Scientist at St. Michael’s Hospital. She is an Assistant Professor at the University of Toronto and an Adjunct Professor at Ryerson University. Her laboratory is located at the Li Ka Shing Knowledge Institute, near the institute of Biomedical Engineering Science and Technology (iBEST) and Biomedical Zone. She performs basic science and clinical translation research developing non-invasive optical technologies to assess skin physiology. Her research aims are to bring innovative technology from the bench to the bedside.

Dr. Cross has won several National and International awards related to her research such as the Wound Healing Society Young Investigator Award, Trauma Association of Canada Research Award, and Best Clinical Research from the Canadian Society of Plastic Surgeons. She has been recognized for her excellence in as a teacher, her collegiality, generosity, mentorship and humanitarianism by receiving the Dr. Hugh Thompson Humanitarian Award and the Leo Mahoney Teaching Award.

Please note: Dr. Cross is not taking any summer students in 2018.

Recent Publications

  1. Chang, YR, Perry, J, Cross, K. Low-Frequency Ultrasound Debridement in Chronic Wound Healing: A Systematic Review of Current Evidence. Plast Surg (Oakv). 2017;25 (1):21-26. doi: 10.1177/2292550317693813. PubMed PMID:29026808 PubMed Central PMC5626185.
  2. Roy, M, Hunter, P, Perry, JA, Cross, KM. Development of a Universal Nutritional Screening Platform for Plastic Surgery Patients. Plast Reconstr Surg Glob Open. 2017;5 (7):e1342. doi: 10.1097/GOX.0000000000001342. PubMed PMID:28831332 PubMed Central PMC5548555.
  3. Yu, J, Hunter, PJ, Perry, JA, Cross, KM. Plastic Surgery Patients Are Malnourished: Utilizing the Canadian Malnutrition Screening Tool. Plast Reconstr Surg Glob Open. 2016;4 (9):e1058. doi: 10.1097/GOX.0000000000001058. PubMed PMID:27757360 PubMed Central PMC5055026.
  4. Yu, J, Lu, S, McLaren, AM, Perry, JA, Cross, KM. Topical oxygen therapy results in complete wound healing in diabetic foot ulcers. Wound Repair Regen. 2016;24 (6):1066-1072. doi: 10.1111/wrr.12490. PubMed PMID:27733020 .
  5. Saiko, G, Cross, K, Douplik, A. Mathematical Model of an Innate Immune Response to Cutaneous Wound in the Presence of Local Hypoxia. Adv. Exp. Med. Biol. ;923 :427-433. doi: 10.1007/978-3-319-38810-6_56. PubMed PMID:27526173 .
  6. Yu, M, Cross, K, Petrich, A, Fish, J. Crib Mattress Investigation: A quality improvement study to assess mattress cover permeability and bacterial growth in crib mattresses. Am J Infect Control. 2016;44 (7):837-9. doi: 10.1016/j.ajic.2015.12.014. PubMed PMID:26856469 .
  7. Farhangkhoee, H, Cross, KM, Koljonen, V, Ghazarian, D, Fish, JS. Evaluation of Ki-67 as a histological index of burn damage in a swine model. J Burn Care Res. ;33 (2):e55-62. doi: 10.1097/BCR.0b013e318233595c. PubMed PMID:21979846 .
  8. Cross, KM, Leonardi, L, Gomez, M, Freisen, JR, Levasseur, MA, Schattka, BJ et al.. Noninvasive measurement of edema in partial thickness burn wounds. J Burn Care Res. ;30 (5):807-17. doi: 10.1097/BCR.0b013e3181b485e9. PubMed PMID:19692905 .
  9. Wong, W, Cross, K, Mahoney, J. Avulsion of the flexor digitorum tendon secondary to enchondroma of the distal phalanx. Can J Plast Surg. 2004;12 (2):67-8. . PubMed PMID:24115877 PubMed Central PMC3792809.
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Affiliations & Other Activities

  • Assistant Professor, Department of Surgery, University of Toronto
  • Adjunct Professor, Ryerson Unversity