Kim A. Connelly

FRACP, PhD, MBBS

Scientist, Keenan Research Centre for Biomedical Science

Biography

Dr. Kim Connelly is a Cardiologist and Scientist who is both nationally recognized as an expert in human and rodent echocardiography, cardiovascular MRI and the impact of diabetes upon cardiac function. His work has been recognized evident by winning the “Young Investigator of the Year Award” in 2012 by the Canadian Cardiovascular Society an Early Researcher Award in 2014, and a Canadian Institutes of Health Research (CIHR) New Investigator award in 2014.

Dr. Connelly runs a basic research laboratory at the Keenan Research Centre for Biomedical Science (KRCBS) at St. Michael’s Hospital where he focuses upon basic mechanisms of disease – primarily around the role of pathological extracellular matrix accumulation and the pro-sclerotic cytokine transforming growth factor beta, with a focus upon translating discoveries into therapies in humans. He is the Director of the Krembil Stem Cell Facility at St. Michael’s Hospital and uses stem cell based therapies to improve cardiac and renal dysfunction as a result of diabetes. He collaborates extensively not only locally in Toronto but also nationally and internationally – with research support from the Heart and Stroke Foundation (HSF) of Canada, CIHR and Canadian Foundation for Innovation along with significant research support from the pharmaceutical industry.

Locally, he sits on the executive of the University of Toronto Cardiovascular research network, and has been a reviewer for both the CIHR “CSB” panel, along with the Heart and Stroke Foundation of Canada (HSF). He was the national spokesperson for the HSF of Canada “heart healthy month” in February 2015.

Recent Publications

  1. Miura, M, Alessandrini, H, Alkhodair, A, Attinger-Toller, A, Biasco, L, Lurz, P et al.. Impact of Massive or Torrential Tricuspid Regurgitation in Patients Undergoing Transcatheter Tricuspid Valve Intervention. JACC Cardiovasc Interv. 2020;13 (17):1999-2009. doi: 10.1016/j.jcin.2020.05.011. PubMed PMID:32912460 .
  2. Huang, F, Connelly, PW, Prasad, GVR, Nash, MM, Gunaratnam, L, Deva, DP et al.. Evaluation of left atrial remodeling in kidney transplant patients using cardiac magnetic resonance imaging. J. Nephrol. 2020; :. doi: 10.1007/s40620-020-00853-7. PubMed PMID:32910428 .
  3. Garg, V, Verma, S, Connelly, KA, Yan, AT, Sikand, A, Garg, A et al.. Does empagliflozin modulate the autonomic nervous system among individuals with type 2 diabetes and coronary artery disease? The EMPA-HEART CardioLink-6 Holter analysis. Metabol Open. 2020;7 :100039. doi: 10.1016/j.metop.2020.100039. PubMed PMID:32812924 PubMed Central PMC7424781.
  4. Roifman, I, Li, M, Connelly, KA. Novel Combined Clinical and Research Protocol to Reduce Wait Times for Cardiac Magnetic Resonance. Healthc Q. 2020;23 (2):62-66. doi: 10.12927/hcq.2020.26272. PubMed PMID:32762823 .
  5. Verma, S, Klug, E, Mareev, VY, Kobalava, ZD, Connelly, KA, Arici, M et al.. Sodium-glucose cotransporter 2 inhibitors at the intersection of cardiovascular, renal and metabolic care: an integrated and multidisciplinary approach to patient-centered care. Curr. Opin. Cardiol. 2020;35 (5):589-601. doi: 10.1097/HCO.0000000000000774. PubMed PMID:32694262 .
  6. Cai, S, Bowers, N, Dhoot, A, Ho, EC, Ong, G, Eckstein, J et al.. Natural history of severe tricuspid regurgitation: Outcomes after transcatheter tricuspid valve intervention compared to medical therapy. Int. J. Cardiol. 2020; :. doi: 10.1016/j.ijcard.2020.07.018. PubMed PMID:32682962 .
  7. Tang, BN, Ong, G, Sandhu, P, Limoges, M, Roifman, I, Johri, AM et al.. Natural History of Left Ventricular Thrombi in Patients with Cardiomyopathy. J Am Soc Echocardiogr. 2020;33 (9):1158-1159. doi: 10.1016/j.echo.2020.05.024. PubMed PMID:32654938 .
  8. Ge, Y, Deva, DP, Connelly, KA, Yan, AT. Stress cardiac MRI in stable coronary artery disease. Curr. Opin. Cardiol. 2020;35 (5):566-573. doi: 10.1097/HCO.0000000000000776. PubMed PMID:32649360 .
  9. Zia, MI, Ramanan, V, Roifman, I, Connelly, KA, Wright, GA, Ghugre, NR et al.. Chronic Persistence of Hemorrhage, Microvascular Obstruction, and Edema After Myocardial Infarction: Utility of Cardiac Magnetic Resonance Imaging. Can J Cardiol. 2020;36 (8):1326.e17-1326.e19. doi: 10.1016/j.cjca.2020.03.045. PubMed PMID:32634391 .
  10. Chow, BJW, Coyle, D, Hossain, A, Laine, M, Hanninen, H, Ukkonen, H et al.. Computed tomography coronary angiography for patients with heart failure (CTA-HF): a randomized controlled trial (IMAGE-HF 1C). Eur Heart J Cardiovasc Imaging. 2020; :. doi: 10.1093/ehjci/jeaa109. PubMed PMID:32588042 .
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Affiliations & Other Activities

  • Director, Krembil Stem Cell Facility, St. Michael’s Hospital
  • Staff Cardiologist, Division of Cardiology, St. Michael’s Hospital
  • Member, Richard Lewar Center, University of Toronto
  • Cardiologist, Division of Cardiology, Sunnybrook Health Sciences Centre
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