Laurie Morrison

MD, FRCPC, MSc

Scientist

Biography

Dr. Morrison is a Professor and Clinician Scientist in the Division of Emergency Medicine, Department of Medicine at the University of Toronto and Li Ka Shing Knowledge Institute at St Michael’s Hospital.  She held the Robert and Dorothy Pitts Chair of Acute Care and Emergency Medicine from 2008 until 2020.  Her program of research is focused on the evaluation and implementation of time sensitive interventions in acute emergencies.  She conducts clinical trials, systematic reviews and meta-analyses in topics pertaining to Resuscitation and Emergency Medicine.  She established a collaborative prehospital research network to conduct randomized controlled trials and outcome validation studies in resuscitation research (cardiac arrest and trauma) on behalf of the Rescu Investigators. (Resuscitation Outcomes Consortium, Canadian CanROC )  She co leads the Canadian COVID-19 Emergency Department Rapid Response Network developing clinical decision rules to guide the emergency management of suspected COVID 19.  She has held research grants from the US National Institute of Health, Canadian Institute of Health Research, Heart and Stroke Foundation of Canada, Laerdal Foundation, Ontario Government, Brain Canada and the American Heart Association.  She has published over 280 papers, held over $17M as a principal investigator and has an h index of 59 (web of science).  She contributed to the development of the 2005 and 2010 and 2015 AHA Guidelines.  She is currently providing scientific oversight of the Continuous Evidence Evaluation strategy for International Liaison Committee on Resuscitation. Dr Morrison is the founding director of the Collaborative Specialization in Resuscitation Sciences program of graduate training at the University of Toronto.  There are 84 students enrolled since inception in 2012 and of these 48 have graduated.  There are over 50 faculty involved from 14 different departments or institutes.  Students have accrued over 1.5M in salary support.  She is the founding director of the biannual Resuscitation in Motion international meeting which brings senior and emerging scientists together in a format conducive to learning, sharing and building capacity in science.  She is founding member and current chair of the Network of Canadian Emergency Medicine Researchers.  This network provides peer review and mentorship of emerging researchers and support for multicenter trials.

Dr Morrison has received the Canadian Medical Association award for excellence in mentorship; the May Cohen award and a similar award from the U of T with the Department of Medicine; Bob Hyland award. She was awarded the William Goldie award from the Department of Medicine at the University of Toronto for outstanding contribution as a leader and scholar in Emergency Medicine.  And, she and her committee were awarded the U of Toronto Helen P. Batty Award in 2014 for Excellence and Achievement in Faculty Development for Sustained Contribution to the field.   She received the distinction of Fellowship in the Canadian Academy of Health Sciences in 2016 and was granted honorary membership by the European Resuscitation Council for life time achievement in 2017.  She was awarded the 2017 Dickinson W. Richards Memorial Lecture by the American Heart Association.

Recent Publications

  1. Orkin, AM, Charles, M, Norris, K, Thomas, R, Chapman, L, Wright, A et al.. Mixed methods feasibility study for the surviving opioid overdose with naloxone education and resuscitation (SOONER) trial. Resusc Plus. 2021;6 :100131. doi: 10.1016/j.resplu.2021.100131. PubMed PMID:34223388 PubMed Central PMC8244470.
  2. Morrison, LJ, Thoma, B. Translating Targeted Temperature Management Trials into Postarrest Care. N Engl J Med. 2021;384 (24):2344-2345. doi: 10.1056/NEJMe2106969. PubMed PMID:34133865 .
  3. Nikolaou, NI, Netherton, S, Welsford, M, Drennan, IR, Nation, K, Belley-Cote, E et al.. A systematic review and meta-analysis of the effect of routine early angiography in patients with return of spontaneous circulation after Out-of-Hospital Cardiac Arrest. Resuscitation. 2021;163 :28-48. doi: 10.1016/j.resuscitation.2021.03.019. PubMed PMID:33838169 .
  4. Hohl, CM, Rosychuk, RJ, McRae, AD, Brooks, SC, Archambault, P, Fok, PT et al.. Development of the Canadian COVID-19 Emergency Department Rapid Response Network population-based registry: a methodology study. CMAJ Open. ;9 (1):E261-E270. doi: 10.9778/cmajo.20200290. PubMed PMID:33731427 PubMed Central PMC8096396.
  5. Ohshimo, S, Wang, CH, Couto, TB, Bingham, R, Mok, YH, Kleinman, M et al.. Pediatric timing of epinephrine doses: A systematic review. Resuscitation. 2021;160 :106-117. doi: 10.1016/j.resuscitation.2021.01.015. PubMed PMID:33529645 .
  6. Mody, P, Pandey, A, Slutsky, AS, Segar, MW, Kiss, A, Dorian, P et al.. Gender-Based Differences in Outcomes Among Resuscitated Patients With Out-of-Hospital Cardiac Arrest. Circulation. 2021;143 (7):641-649. doi: 10.1161/CIRCULATIONAHA.120.050427. PubMed PMID:33317326 PubMed Central PMC8259883.
  7. Drennan, IR, Dorian, P, McLeod, S, Pinto, R, Scales, DC, Turner, L et al.. DOuble SEquential External Defibrillation for Refractory Ventricular Fibrillation (DOSE VF): study protocol for a randomized controlled trial. Trials. 2020;21 (1):977. doi: 10.1186/s13063-020-04904-z. PubMed PMID:33243277 PubMed Central PMC7689391.
  8. Dixon, AL, McCully, BH, Rick, EA, Dewey, E, Farrell, DH, Morrison, LJ et al.. Tranexamic acid administration in the field does not affect admission thromboelastography after traumatic brain injury. J Trauma Acute Care Surg. 2020;89 (5):900-907. doi: 10.1097/TA.0000000000002932. PubMed PMID:33105308 PubMed Central PMC7878849.
  9. Grunau, B, Kime, N, Leroux, B, Rea, T, Van Belle, G, Menegazzi, JJ et al.. Association of Intra-arrest Transport vs Continued On-Scene Resuscitation With Survival to Hospital Discharge Among Patients With Out-of-Hospital Cardiac Arrest. JAMA. 2020;324 (11):1058-1067. doi: 10.1001/jama.2020.14185. PubMed PMID:32930759 PubMed Central PMC7492914.
  10. Rowell, SE, Meier, EN, McKnight, B, Kannas, D, May, S, Sheehan, K et al.. Effect of Out-of-Hospital Tranexamic Acid vs Placebo on 6-Month Functional Neurologic Outcomes in Patients With Moderate or Severe Traumatic Brain Injury. JAMA. 2020;324 (10):961-974. doi: 10.1001/jama.2020.8958. PubMed PMID:32897344 PubMed Central PMC7489866.
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Affiliations & Other Activities

  • Scientist, Li Ka Shing Knowledge Institute, St. Michael’s Hospital
  • Clinician Scientist, Emergency Medicine, LKSKI, University of Toronto
  • Director, Collaborative Program in Resuscitation Sciences, University of Toronto
  • Professor, Medicine, University of Toronto
  • Professor, Health Policy, Management and Evaluation, University of Toronto
  • Full member, School of Graduate Studies, University of Toronto
  • Member, Institute of Medical Science, University of Toronto
  • Robert and Dorothy Pitts Chair in Acute Care & Emergency Medicine, St. Michael’s Hospital
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