Mark Peterson


Associate Scientist, Li Ka Shing Knowledge Institute


Please note: For all inquiries regarding research volunteer/student positions, please email Alana Harrington (Research Manager) directly:

I am interested in the clinical outcomes of patients with a wide range of aortic disease, including aortic valvular disease, following both conventional surgery as well as endovascular or percutaneous intervention. St. Michael’s Hospital participates in the International Registry of Acute Aortic Dissection study, which prospectively collects data on patients with either Type A or Type B dissections in 24 centers around the world. We are in the process of developing a National Aortic and Endovascular Surgery Registry to prospectively study patients undergoing either conventional surgery or endovascular surgery in major centers across Canada. I am also interested in the basic biology of aneurysm formation and aneurysm regression following endovascular stent-grafting.

Recent Publications

  1. Bendayan, M, Messas, N, Perrault, LP, Asgar, AW, Lauck, S, Kim, DH et al.. Frailty and Bleeding in Older Adults Undergoing TAVR or SAVR: Insights From the FRAILTY-AVR Study. JACC Cardiovasc Interv. 2020;13 (9):1058-1068. doi: 10.1016/j.jcin.2020.01.238. PubMed PMID:32381184 .
  2. Chung, JC, Lodewyks, CL, Forbes, TL, Chu, MWA, Peterson, MD, Arora, RC et al.. Prevention and management of spinal cord ischemia following aortic surgery: A survey of contemporary practice. J. Thorac. Cardiovasc. Surg. 2020; :. doi: 10.1016/j.jtcvs.2020.03.034. PubMed PMID:32334886 .
  3. Chung, J, Stevens, LM, Chu, MWA, Dagenais, F, Peterson, MD, Boodhwani, M et al.. The impact of age on patients undergoing aortic arch surgery: Evidence from a multicenter national registry. J. Thorac. Cardiovasc. Surg. 2020; :. doi: 10.1016/j.jtcvs.2020.02.032. PubMed PMID:32178917 .
  4. Fam, NP, Ong, G, Deva, DP, Peterson, MD. Transfemoral Transcatheter Tricuspid Valve Replacement. JACC Cardiovasc Interv. 2020;13 (10):e93-e94. doi: 10.1016/j.jcin.2020.01.194. PubMed PMID:32171717 .
  5. Hage, A, Stevens, LM, Ouzounian, M, Chung, J, El-Hamamsy, I, Chauvette, V et al.. Impact of brain protection strategies on mortality and stroke in patients undergoing aortic arch repair with hypothermic circulatory arrest: evidence from the Canadian Thoracic Aortic Collaborative. Eur J Cardiothorac Surg. 2020;58 (1):95-103. doi: 10.1093/ejcts/ezaa023. PubMed PMID:32034910 .
  6. Elbatarny, M, Tam, DY, Edelman, JJ, Rocha, RV, Chu, MWA, Peterson, MD et al.. Valve-Sparing Root Replacement Versus Composite Valve Grafting in Aortic Root Dilation: A Meta-Analysis. Ann. Thorac. Surg. 2020;110 (1):296-306. doi: 10.1016/j.athoracsur.2019.11.054. PubMed PMID:31981499 .
  7. Sathananthan, J, Lauck, S, Piazza, N, Martucci, G, Kim, DH, Popma, JJ et al.. Habitual Physical Activity in Older Adults Undergoing TAVR: Insights From the FRAILTY-AVR Study. JACC Cardiovasc Interv. 2019;12 (8):781-789. doi: 10.1016/j.jcin.2019.02.049. PubMed PMID:31000014 .
  8. Pighi, M, Piazza, N, Martucci, G, Lachapelle, K, Perrault, LP, Asgar, AW et al.. Sex-Specific Determinants of Outcomes After Transcatheter Aortic Valve Replacement. Circ Cardiovasc Qual Outcomes. 2019;12 (3):e005363. doi: 10.1161/CIRCOUTCOMES.118.005363. PubMed PMID:30879326 .
  9. Sibilio, S, Koziarz, A, Belley-Côté, EP, McClure, GR, MacIsaac, S, Reza, SJ et al.. Outcomes after Ross procedure in adult patients: A meta-analysis and microsimulation. J Card Surg. 2019;34 (5):285-292. doi: 10.1111/jocs.14020. PubMed PMID:30866116 .
  10. Chung, J, Stevens, LM, Ouzounian, M, El-Hamamsy, I, Bouhout, I, Dagenais, F et al.. Sex-Related Differences in Patients Undergoing Thoracic Aortic Surgery. Circulation. 2019;139 (9):1177-1184. doi: 10.1161/CIRCULATIONAHA.118.035805. PubMed PMID:30755026 .
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Affiliations & Other Activities

  • Associate Professor, Department of Surgery, University of Toronto