Mark Peterson


Associate Scientist, Li Ka Shing Knowledge Institute


I am interested in the clinical outcomes of patients with a wide range of aortic disease, including aortic valvular disease, following both conventional surgery as well as endovascular or percutaneous intervention. St. Michael’s Hospital participates in the International Registry of Acute Aortic Dissection study, which prospectively collects data on patients with either Type A or Type B dissections in 24 centers around the world. We are in the process of developing a National Aortic and Endovascular Surgery Registry to prospectively study patients undergoing either conventional surgery or endovascular surgery in major centers across Canada. I am also interested in the basic biology of aneurysm formation and aneurysm regression following endovascular stent-grafting.

Recent Publications

  1. Wassef, AWA, Alnasser, S, Rodes-Cabau, J, Webb, JG, Barbanti, M, Liu, Y et al.. Institutional experience and outcomes of transcatheter aortic valve replacement: Results from an international multicentre registry. Int. J. Cardiol. 2017; :. doi: 10.1016/j.ijcard.2017.07.079. PubMed PMID:28760395 .
  2. Afilalo, J, Lauck, S, Kim, DH, Lefèvre, T, Piazza, N, Lachapelle, K et al.. Frailty in Older Adults Undergoing Aortic Valve Replacement: The FRAILTY-AVR Study. J. Am. Coll. Cardiol. 2017;70 (6):689-700. doi: 10.1016/j.jacc.2017.06.024. PubMed PMID:28693934 .
  3. Pelletier, MP, Kaneko, T, Peterson, MD, Thourani, VH. From sutures to wires: The evolving necessities of cardiac surgery training. J. Thorac. Cardiovasc. Surg. 2017; :. doi: 10.1016/j.jtcvs.2017.03.157. PubMed PMID:28645829 .
  4. Garg, V, Peterson, MD, Chu, MW, Ouzounian, M, MacArthur, RG, Bozinovski, J et al.. Axillary versus innominate artery cannulation for antegrade cerebral perfusion in aortic surgery: design of the Aortic Surgery Cerebral Protection Evaluation (ACE) CardioLink-3 randomised trial. BMJ Open. 2017;7 (6):e014491. doi: 10.1136/bmjopen-2016-014491. PubMed PMID:28601820 .
  5. Czarnecki, A, Qiu, F, Koh, M, Prasad, TJ, Cantor, WJ, Cheema, AN et al.. Clinical outcomes after trans-catheter aortic valve replacement in men and women in Ontario, Canada. Catheter Cardiovasc Interv. 2017; :. doi: 10.1002/ccd.26906. PubMed PMID:28145088 .
  6. Bossone, E, Pyeritz, RE, Braverman, AC, Peterson, MD, Ehrlich, M, O'Gara, P et al.. Shock complicating type A acute aortic dissection: Clinical correlates, management, and outcomes. Am. Heart J. 2016;176 :93-9. doi: 10.1016/j.ahj.2016.02.019. PubMed PMID:27264225 .
  7. Appoo, JJ, Bozinovski, J, Chu, MW, El-Hamamsy, I, Forbes, TL, Moon, M et al.. Canadian Cardiovascular Society/Canadian Society of Cardiac Surgeons/Canadian Society for Vascular Surgery Joint Position Statement on Open and Endovascular Surgery for Thoracic Aortic Disease. Can J Cardiol. 2016;32 (6):703-13. doi: 10.1016/j.cjca.2015.12.037. PubMed PMID:27233892 .
  8. Michler, RE, Smith, PK, Parides, MK, Ailawadi, G, Thourani, V, Moskowitz, AJ et al.. Two-Year Outcomes of Surgical Treatment of Moderate Ischemic Mitral Regurgitation. N. Engl. J. Med. 2016;374 (20):1932-41. doi: 10.1056/NEJMoa1602003. PubMed PMID:27040451 PubMed Central PMC4908820.
  9. Yeung, JC, Marcuzzi, D, Peterson, MD, Ko, MA. Management of severe asymmetric pectus excavatum complicating aortic repair in a patient with Marfan's syndrome. Interact Cardiovasc Thorac Surg. 2016;22 (5):674-5. doi: 10.1093/icvts/ivv400. PubMed PMID:26874148 PubMed Central PMC4892142.
  10. Garg, V, Ouzounian, M, Peterson, MD. Advances in aortic disease management: a year in review. Curr. Opin. Cardiol. 2016;31 (2):127-31. doi: 10.1097/HCO.0000000000000267. PubMed PMID:26766164 .
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Affiliations & Other Activities

  • Associate Professor, Surgery/Cardiac Surgery, University of Toronto