Mark Peterson


Associate Scientist, Li Ka Shing Knowledge Institute


I am interested in the clinical outcomes of patients with a wide range of aortic disease, including aortic valvular disease, following both conventional surgery as well as endovascular or percutaneous intervention. St. Michael’s Hospital participates in the International Registry of Acute Aortic Dissection study, which prospectively collects data on patients with either Type A or Type B dissections in 24 centers around the world. We are in the process of developing a National Aortic and Endovascular Surgery Registry to prospectively study patients undergoing either conventional surgery or endovascular surgery in major centers across Canada. I am also interested in the basic biology of aneurysm formation and aneurysm regression following endovascular stent-grafting.

Recent Publications

  1. Goldfarb, M, Lauck, S, Webb, JG, Asgar, AW, Perrault, LP, Piazza, N et al.. Malnutrition and Mortality in Frail and Non-Frail Older Adults Undergoing Aortic Valve Replacement. Circulation. 2018; :. doi: 10.1161/CIRCULATIONAHA.118.033887. PubMed PMID:29976568 .
  2. Hanif, H, Dubois, L, Ouzounian, M, Peterson, MD, El-Hamamsy, I, Dagenais, F et al.. Aortic Arch Reconstructive Surgery With Conventional Techniques vs Frozen Elephant Trunk: A Systematic Review and Meta-Analysis. Can J Cardiol. 2018;34 (3):262-273. doi: 10.1016/j.cjca.2017.12.020. PubMed PMID:29395709 .
  3. Drudi, LM, Ades, M, Turkdogan, S, Huynh, C, Lauck, S, Webb, JG et al.. Association of Depression With Mortality in Older Adults Undergoing Transcatheter or Surgical Aortic Valve Replacement. JAMA Cardiol. 2018;3 (3):191-197. doi: 10.1001/jamacardio.2017.5064. PubMed PMID:29344620 PubMed Central PMC5885887.
  4. Ong, G, Redfors, B, Crowley, A, Abdel-Qadir, H, Harrington, A, Liu, Y et al.. Evaluation of left ventricular reverse remodeling in patients with severe aortic regurgitation undergoing aortic valve replacement: Comparison between diameters and volumes. Echocardiography. 2018;35 (2):142-147. doi: 10.1111/echo.13750. PubMed PMID:29193376 .
  5. Froehlich, W, Tolenaar, JL, Harris, KM, Strauss, C, Sundt, TM, Tsai, TT et al.. Delay from Diagnosis to Surgery in Transferred Type A Aortic Dissection. Am. J. Med. 2018;131 (3):300-306. doi: 10.1016/j.amjmed.2017.11.009. PubMed PMID:29180025 .
  6. Costin, NI, Korach, A, Loor, G, Peterson, MD, Desai, ND, Trimarchi, S et al.. Patients With Type A Acute Aortic Dissection Presenting With an Abnormal Electrocardiogram. Ann. Thorac. Surg. 2018;105 (1):92-99. doi: 10.1016/j.athoracsur.2017.06.063. PubMed PMID:29074152 .
  7. Larsen, M, Trimarchi, S, Patel, HJ, Di Eusanio, M, Greason, KL, Peterson, MD et al.. Extended versus limited arch replacement in acute Type A aortic dissection. Eur J Cardiothorac Surg. 2017;52 (6):1104-1110. doi: 10.1093/ejcts/ezx214. PubMed PMID:28977503 .
  8. Kiser, AC, Caranasos, TG, Peterson, MD, Buller, CE, Borger, MA. Suprasternal Aortic Valve Replacement: Key Technology and Techniques. Ann. Thorac. Surg. 2017;104 (4):1417-1422. doi: 10.1016/j.athoracsur.2017.04.032. PubMed PMID:28935306 .
  9. Regueiro, A, Ye, J, Fam, N, Bapat, VN, Dagenais, F, Peterson, MD et al.. 2-Year Outcomes After Transcatheter Mitral Valve Replacement. JACC Cardiovasc Interv. 2017;10 (16):1671-1678. doi: 10.1016/j.jcin.2017.05.032. PubMed PMID:28838478 .
  10. Nauta, FJH, Kim, JB, Patel, HJ, Peterson, MD, Eckstein, HH, Khoynezhad, A et al.. Early Outcomes of Acute Retrograde Dissection From the International Registry of Acute Aortic Dissection. Semin. Thorac. Cardiovasc. Surg. ;29 (2):150-159. doi: 10.1053/j.semtcvs.2016.10.004. PubMed PMID:28823321 .
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Affiliations & Other Activities

  • Associate Professor, Department of Surgery, University of Toronto