Mark Peterson


Associate Scientist, Li Ka Shing Knowledge Institute


I am interested in the clinical outcomes of patients with a wide range of aortic disease, including aortic valvular disease, following both conventional surgery as well as endovascular or percutaneous intervention. St. Michael’s Hospital participates in the International Registry of Acute Aortic Dissection study, which prospectively collects data on patients with either Type A or Type B dissections in 24 centers around the world. We are in the process of developing a National Aortic and Endovascular Surgery Registry to prospectively study patients undergoing either conventional surgery or endovascular surgery in major centers across Canada. I am also interested in the basic biology of aneurysm formation and aneurysm regression following endovascular stent-grafting.

Recent Publications

  1. Larsen, M, Trimarchi, S, Patel, HJ, Di Eusanio, M, Greason, KL, Peterson, MD et al.. Extended versus limited arch replacement in acute Type A aortic dissection. Eur J Cardiothorac Surg. 2017; :. doi: 10.1093/ejcts/ezx214. PubMed PMID:28977503 .
  2. Kiser, AC, Caranasos, TG, Peterson, MD, Buller, CE, Borger, MA. Suprasternal Aortic Valve Replacement: Key Technology and Techniques. Ann. Thorac. Surg. 2017;104 (4):1417-1422. doi: 10.1016/j.athoracsur.2017.04.032. PubMed PMID:28935306 .
  3. Regueiro, A, Ye, J, Fam, N, Bapat, VN, Dagenais, F, Peterson, MD et al.. 2-Year Outcomes After Transcatheter Mitral Valve Replacement. JACC Cardiovasc Interv. 2017;10 (16):1671-1678. doi: 10.1016/j.jcin.2017.05.032. PubMed PMID:28838478 .
  4. Nauta, FJH, Kim, JB, Patel, HJ, Peterson, MD, Eckstein, HH, Khoynezhad, A et al.. Early Outcomes of Acute Retrograde Dissection From the International Registry of Acute Aortic Dissection. Semin. Thorac. Cardiovasc. Surg. ;29 (2):150-159. doi: 10.1053/j.semtcvs.2016.10.004. PubMed PMID:28823321 .
  5. Wassef, AWA, Alnasser, S, Rodes-Cabau, J, Webb, JG, Barbanti, M, Liu, Y et al.. Institutional experience and outcomes of transcatheter aortic valve replacement: Results from an international multicentre registry. Int. J. Cardiol. 2017;245 :222-227. doi: 10.1016/j.ijcard.2017.07.079. PubMed PMID:28760395 .
  6. Afilalo, J, Lauck, S, Kim, DH, Lefèvre, T, Piazza, N, Lachapelle, K et al.. Frailty in Older Adults Undergoing Aortic Valve Replacement: The FRAILTY-AVR Study. J. Am. Coll. Cardiol. 2017;70 (6):689-700. doi: 10.1016/j.jacc.2017.06.024. PubMed PMID:28693934 .
  7. Pelletier, MP, Kaneko, T, Peterson, MD, Thourani, VH. From sutures to wires: The evolving necessities of cardiac surgery training. J. Thorac. Cardiovasc. Surg. 2017;154 (3):990-993. doi: 10.1016/j.jtcvs.2017.03.157. PubMed PMID:28645829 .
  8. Garg, V, Peterson, MD, Chu, MW, Ouzounian, M, MacArthur, RG, Bozinovski, J et al.. Axillary versus innominate artery cannulation for antegrade cerebral perfusion in aortic surgery: design of the Aortic Surgery Cerebral Protection Evaluation (ACE) CardioLink-3 randomised trial. BMJ Open. 2017;7 (6):e014491. doi: 10.1136/bmjopen-2016-014491. PubMed PMID:28601820 PubMed Central PMC5623414.
  9. Czarnecki, A, Qiu, F, Koh, M, Prasad, TJ, Cantor, WJ, Cheema, AN et al.. Clinical outcomes after trans-catheter aortic valve replacement in men and women in Ontario, Canada. Catheter Cardiovasc Interv. 2017;90 (3):486-494. doi: 10.1002/ccd.26906. PubMed PMID:28145088 .
  10. Bossone, E, Pyeritz, RE, Braverman, AC, Peterson, MD, Ehrlich, M, O'Gara, P et al.. Shock complicating type A acute aortic dissection: Clinical correlates, management, and outcomes. Am. Heart J. 2016;176 :93-9. doi: 10.1016/j.ahj.2016.02.019. PubMed PMID:27264225 .
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Affiliations & Other Activities

  • Associate Professor, Department of Surgery, University of Toronto