Matthew Muller




Dr. Matthew Muller is an infectious diseases physician and the Medical Director of Infection Prevention and Control at Unity Health Toronto. He is an Associate Professor at the University of Toronto in the Department of Medicine. His research interests are focused on the epidemiology and previous of hospital-acquired infections including C. difficile, infections due to common antibiotic-resistant organisms and emerging infectious threats such as MERS-CoV and SARS-CoV2. Dr. Muller has a particular interest in hand hygiene measurement and improvement including the use of novel technological approaches to hand hygiene improvement. Dr. Muller chairs the Provincial Infectious Diseases Advisory Committee on Infection Prevention and Control, and is also interested in guideline and policy development with respect to infection prevention for Ontario hospitals.

Recent Publications

  1. Sniekers, DC, Jung, JKH, Blake, PG, Cooper, R, Leis, JA, Muller, MP et al.. Province-Wide Prevalence Testing for SARS-CoV-2 of In-Center Hemodialysis Patients and Staff in Ontario, Canada: A Cross-Sectional Study. Can J Kidney Health Dis. 2021;8 :20543581211036213. doi: 10.1177/20543581211036213. PubMed PMID:34394945 PubMed Central PMC8358577.
  2. Schwartz, KL, Muller, MP, Williams, V, Harry, R, Booker, S, Katz, K et al.. Coronavirus disease 2019 (COVID-19) risk among healthcare workers performing nasopharyngeal testing. Infect Control Hosp Epidemiol. 2021; :1-3. doi: 10.1017/ice.2021.354. PubMed PMID:34338181 PubMed Central PMC8387686.
  3. Paphitis, K, Achonu, C, Callery, S, Gubbay, J, Katz, K, Muller, M et al.. Beyond flu: Trends in respiratory infection outbreaks in Ontario healthcare settings from 2007 to 2017, and implications for non-influenza outbreak management. Can Commun Dis Rep. 2021;47 (56):269-275. doi: 10.14745/ccdr.v47i56a04. PubMed PMID:34220351 PubMed Central PMC8219065.
  4. Tan, DHS, Chan, AK, Jüni, P, Tomlinson, G, Daneman, N, Walmsley, S et al.. Post-exposure prophylaxis against SARS-CoV-2 in close contacts of confirmed COVID-19 cases (CORIPREV): study protocol for a cluster-randomized trial. Trials. 2021;22 (1):224. doi: 10.1186/s13063-021-05134-7. PubMed PMID:33752741 PubMed Central PMC7982877.
  5. Leis, JA, Muller, MP. Reply to Cawthorne and Cooke. Clin Infect Dis. 2021;73 (1):e278-e279. doi: 10.1093/cid/ciaa1924. PubMed PMID:33386404 .
  6. Kohler, P, Tijet, N, Kim, HC, Johnstone, J, Edge, T, Patel, SN et al.. Dissemination of Verona Integron-encoded Metallo-β-lactamase among clinical and environmental Enterobacteriaceae isolates in Ontario, Canada. Sci Rep. 2020;10 (1):18580. doi: 10.1038/s41598-020-75247-7. PubMed PMID:33122675 PubMed Central PMC7596063.
  7. Kandel, CE, Jenkinson, R, Widdifield, J, Hansen, BE, Davey, JR, Muller, MP et al.. Identification of prosthetic hip and knee joint infections using administrative databases-A validation study. Infect Control Hosp Epidemiol. 2021;42 (3):325-330. doi: 10.1017/ice.2020.449. PubMed PMID:32993826 .
  8. Rios, P, Radhakrishnan, A, Williams, C, Ramkissoon, N, Pham, B, Cormack, GV et al.. Preventing the transmission of COVID-19 and other coronaviruses in older adults aged 60 years and above living in long-term care: a rapid review. Syst Rev. 2020;9 (1):218. doi: 10.1186/s13643-020-01486-4. PubMed PMID:32977848 PubMed Central PMC7517751.
  9. Mishra, S, Wang, L, Ma, H, Yiu, KCY, Paterson, JM, Kim, E et al.. Estimated surge in hospital and intensive care admission because of the coronavirus disease 2019 pandemic in the Greater Toronto Area, Canada: a mathematical modelling study. CMAJ Open. ;8 (3):E593-E604. doi: 10.9778/cmajo.20200093. PubMed PMID:32963024 PubMed Central PMC7641231.
  10. Kovacs-Litman, A, Muller, MP, Powis, JE, Ricciuto, D, McGeer, A, Williams, V et al.. Association between hospital outbreaks and hand hygiene: Insights from electronic monitoring. Clin Infect Dis. 2020; :. doi: 10.1093/cid/ciaa1405. PubMed PMID:32936910 .
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Affiliations & Other Activities

  • Medical Director, Infection Prevention and Control, St. Michael’s Hospital
  • Assistant Professor, Department of Medicine, University of Toronto