Matthew Muller


Associate Scientist, Li Ka Shing Knowledge Institute


Dr. Matthew Muller is an infectious diseases physician and the Medical Director of Infection Prevention and Control at St. Michael’s Hospital. He is an Assistant Professor at the University of Toronto in the Department of Medicine. His research interests are focused on the epidemiology and previous of hospital-acquired infections including C. difficile, infections due to common antibiotic-resistant organisms and emerging infectious threats such as MERS-CoV. Dr. Muller has a particular interest in hand hygiene measurement and improvement including the use of novel technological approaches to hand hygiene improvement. Dr. Muller chairs the Provincial Infectious Diseases Advisory Committee on Infection Prevention and Control, and is also interested in guideline and policy development with respect to infection prevention for Ontario hospitals.


Recent Publications

  1. Kandel, CE, Jenkinson, R, Daneman, N, Backstein, D, Hansen, BE, Muller, MP et al.. Predictors of Treatment Failure for Hip and Knee Prosthetic Joint Infections in the Setting of 1- and 2-Stage Exchange Arthroplasty: A Multicenter Retrospective Cohort. Open Forum Infect Dis. 2019;6 (11):ofz452. doi: 10.1093/ofid/ofz452. PubMed PMID:31737739 PubMed Central PMC6847009.
  2. Blanchard, AC, Tang, L, Tadros, M, Muller, M, Spilker, T, Waters, VJ et al.. Burkholderia cenocepacia ET12 transmission in adults with cystic fibrosis. Thorax. 2019; :. doi: 10.1136/thoraxjnl-2019-214098. PubMed PMID:31732688 .
  3. Tadros, M, Cabrera, A, Matukas, LM, Muller, M. Evaluation of Matrix-Assisted Laser Desorption Ionization Time-of-Flight Mass Spectrometry and ClinPro Tools as a Rapid Tool for Typing Streptococcus pyogenes. Open Forum Infect Dis. 2019;6 (11):ofz441. doi: 10.1093/ofid/ofz441. PubMed PMID:31700941 PubMed Central PMC6825801.
  4. Jamal, AJ, Garcia-Jeldes, F, Baqi, M, Borgia, S, Johnstone, J, Katz, K et al.. Infection prevention and control practices related to carbapenemase-producing Enterobacteriaceae (CPE) in acute-care hospitals in Ontario, Canada. Infect Control Hosp Epidemiol. 2019;40 (9):1006-1012. doi: 10.1017/ice.2019.173. PubMed PMID:31244458 .
  5. Jiang, L, McGeer, A, McNeil, S, Katz, K, Loeb, M, Muller, MP et al.. Which healthcare workers work with acute respiratory illness? Evidence from Canadian acute-care hospitals during 4 influenza seasons: 2010-2011 to 2013-2014. Infect Control Hosp Epidemiol. 2019;40 (8):889-896. doi: 10.1017/ice.2019.141. PubMed PMID:31208477 .
  6. Garneau, JR, Abou Chakra, CN, Fortier, LC, Labbé, AC, Simor, AE, Gold, W et al.. Multilocus Variable-Number Tandem-Repeat Analysis of Clostridioides difficile Clusters in Ribotype 027 Isolates and Lack of Association with Clinical Outcomes. J. Clin. Microbiol. 2019;57 (5):. doi: 10.1128/JCM.01724-18. PubMed PMID:30760531 PubMed Central PMC6497997.
  7. Kohler, PP, Melano, RG, Patel, SN, Shafinaz, S, Faheem, A, Coleman, BL et al.. Emergence of Carbapenemase-Producing Enterobacteriaceae, South-Central Ontario, Canada1. Emerging Infect. Dis. 2018;24 (9):1674-1682. doi: 10.3201/eid2409.180164. PubMed PMID:30124197 PubMed Central PMC6106407.
  8. Lindsay, PJ, Rohailla, S, Taggart, LR, Lightfoot, D, Havey, T, Daneman, N et al.. Antimicrobial Stewardship and Intensive Care Unit Mortality: A Systematic Review. Clin. Infect. Dis. 2019;68 (5):748-756. doi: 10.1093/cid/ciy550. PubMed PMID:29982376 .
  9. Johnstone, J, Chen, C, Rosella, L, Adomako, K, Policarpio, ME, Lam, F et al.. Patient- and hospital-level predictors of vancomycin-resistant Enterococcus (VRE) bacteremia in Ontario, Canada. Am J Infect Control. 2018;46 (11):1266-1271. doi: 10.1016/j.ajic.2018.05.003. PubMed PMID:29903421 .
  10. Hussain, H, McGeer, A, McNeil, S, Katz, K, Loeb, M, Simor, A et al.. Factors associated with influenza vaccination among healthcare workers in acute care hospitals in Canada. Influenza Other Respir Viruses. 2018;12 (3):319-325. doi: 10.1111/irv.12545. PubMed PMID:29430860 PubMed Central PMC5907810.
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Affiliations & Other Activities

  • Medical Director, Infection Prevention and Control, St. Michael’s Hospital
  • Assistant Professor, Department of Medicine, University of Toronto