Matthew Muller


Associate Scientist, Li Ka Shing Knowledge Institute


Dr. Matthew Muller is an infectious diseases physician and the Medical Director of Infection Prevention and Control at St. Michael’s Hospital. He is an Assistant Professor at the University of Toronto in the Department of Medicine. His research interests are focused on the epidemiology and previous of hospital-acquired infections including C. difficile, infections due to common antibiotic-resistant organisms and emerging infectious threats such as MERS-CoV. Dr. Muller has a particular interest in hand hygiene measurement and improvement including the use of novel technological approaches to hand hygiene improvement. Dr. Muller chairs the Provincial Infectious Diseases Advisory Committee on Infection Prevention and Control, and is also interested in guideline and policy development with respect to infection prevention for Ontario hospitals.


Recent Publications

  1. Hussain, H, McGeer, A, McNeil, S, Katz, K, Loeb, M, Simor, A et al.. Factors associated with influenza vaccination among healthcare workers in acute care hospitals in Canada. Influenza Other Respir Viruses. 2018;12 (3):319-325. doi: 10.1111/irv.12545. PubMed PMID:29430860 PubMed Central PMC5907810.
  2. Muller, MP, Siddiqui, N, Ivancic, R, Wong, D. Adenovirus-related epidemic keratoconjunctivitis outbreak at a hospital-affiliated ophthalmology clinic. Am J Infect Control. 2018;46 (5):581-583. doi: 10.1016/j.ajic.2017.11.011. PubMed PMID:29305276 .
  3. Fralick, M, Haj, R, Hirpara, D, Wong, K, Muller, M, Matukas, L et al.. Can a smartphone app improve medical trainees' knowledge of antibiotics?. Int J Med Educ. 2017;8 :416-420. doi: 10.5116/ijme.5a11.8422. PubMed PMID:29200402 PubMed Central PMC5768437.
  4. Cheng, MP, Bogoch, II, Green, K, Plevneshi, A, Rudnick, W, Shigayeva, A et al.. Factors Associated With 30-Day Mortality Rate in Respiratory Infections Caused by Streptococcus pneumoniae. Clin. Infect. Dis. 2018;66 (8):1282-1285. doi: 10.1093/cid/cix999. PubMed PMID:29140429 .
  5. Coleman, BL, Hassan, K, Green, K, Gubbay, JB, Katz, K, Mazzulli, T et al.. Pre-and post-pandemic trends in antiviral use in hospitalized patients with laboratory-confirmed influenza: 2004/05-2013/14, Toronto, Canada. Antiviral Res. 2017;140 :158-163. doi: 10.1016/j.antiviral.2017.01.025. PubMed PMID:28179155 .
  6. Ng, W, Faheem, A, McGeer, A, Simor, AE, Gelosia, A, Willey, BM et al.. Community- and Healthcare-Associated Methicillin-Resistant Staphylococcus aureus Strains: An Investigation Into Household Transmission, Risk Factors, and Environmental Contamination. Infect Control Hosp Epidemiol. 2017;38 (1):61-67. doi: 10.1017/ice.2016.245. PubMed PMID:27821194 .
  7. Muller, MP. Measuring hand hygiene when it matters. Lancet Infect Dis. 2016;16 (12):1306-1307. doi: 10.1016/S1473-3099(16)30335-8. PubMed PMID:27599873 .
  8. Campigotto, A, Muller, MP, Taggart, LR, Haj, R, Leung, E, Nadarajah, J et al.. Cumulative Antimicrobial Susceptibility Data from Intensive Care Units at One Institution: Should Data Be Combined?. J. Clin. Microbiol. 2016;54 (4):956-9. doi: 10.1128/JCM.02992-15. PubMed PMID:26791365 PubMed Central PMC4809911.
  9. Shigayeva, A, Rudnick, W, Green, K, Tyrrell, G, Demczuk, WH, Gold, WL et al.. Association of serotype with respiratory presentations of pneumococcal infection, Ontario, Canada, 2003-2011. Vaccine. 2016;34 (6):846-53. doi: 10.1016/j.vaccine.2015.11.021. PubMed PMID:26602266 .
  10. Tijet, N, Muller, MP, Matukas, LM, Khan, A, Patel, SN, Melano, RG et al.. Lateral dissemination and inter-patient transmission of blaKPC-3: role of a conjugative plasmid in spreading carbapenem resistance. J. Antimicrob. Chemother. 2016;71 (2):344-7. doi: 10.1093/jac/dkv356. PubMed PMID:26518052 .
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Affiliations & Other Activities

  • Medical Director, Infection Prevention and Control, St. Michael’s Hospital
  • Assistant Professor, Department of Medicine, University of Toronto