Matthew Muller


Associate Scientist, Li Ka Shing Knowledge Institute


Dr. Matthew Muller is an infectious diseases physician and the Medical Director of Infection Prevention and Control at St. Michael’s Hospital. He is an Assistant Professor at the University of Toronto in the Department of Medicine. His research interests are focused on the epidemiology and previous of hospital-acquired infections including C. difficile, infections due to common antibiotic-resistant organisms and emerging infectious threats such as MERS-CoV. Dr. Muller has a particular interest in hand hygiene measurement and improvement including the use of novel technological approaches to hand hygiene improvement. Dr. Muller chairs the Provincial Infectious Diseases Advisory Committee on Infection Prevention and Control, and is also interested in guideline and policy development with respect to infection prevention for Ontario hospitals.


Recent Publications

  1. Garneau, JR, Abou Chakra, CN, Fortier, LC, Labbé, AC, Simor, AE, Gold, W et al.. Multilocus Variable-Number Tandem-Repeat Analysis of Clostridioides difficile Clusters in Ribotype 027 Isolates and Lack of Association with Clinical Outcomes. J. Clin. Microbiol. 2019; :. doi: 10.1128/JCM.01724-18. PubMed PMID:30760531 .
  2. Kohler, PP, Melano, RG, Patel, SN, Shafinaz, S, Faheem, A, Coleman, BL et al.. Emergence of Carbapenemase-Producing Enterobacteriaceae, South-Central Ontario, Canada1. Emerging Infect. Dis. 2018;24 (9):1674-1682. doi: 10.3201/eid2409.180164. PubMed PMID:30124197 PubMed Central PMC6106407.
  3. Lindsay, PJ, Rohailla, S, Taggart, LR, Lightfoot, D, Havey, T, Daneman, N et al.. Antimicrobial Stewardship and Intensive Care Unit Mortality: A Systematic Review. Clin. Infect. Dis. 2019;68 (5):748-756. doi: 10.1093/cid/ciy550. PubMed PMID:29982376 .
  4. Johnstone, J, Chen, C, Rosella, L, Adomako, K, Policarpio, ME, Lam, F et al.. Patient- and hospital-level predictors of vancomycin-resistant Enterococcus (VRE) bacteremia in Ontario, Canada. Am J Infect Control. 2018;46 (11):1266-1271. doi: 10.1016/j.ajic.2018.05.003. PubMed PMID:29903421 .
  5. Hussain, H, McGeer, A, McNeil, S, Katz, K, Loeb, M, Simor, A et al.. Factors associated with influenza vaccination among healthcare workers in acute care hospitals in Canada. Influenza Other Respir Viruses. 2018;12 (3):319-325. doi: 10.1111/irv.12545. PubMed PMID:29430860 PubMed Central PMC5907810.
  6. Muller, MP, Siddiqui, N, Ivancic, R, Wong, D. Adenovirus-related epidemic keratoconjunctivitis outbreak at a hospital-affiliated ophthalmology clinic. Am J Infect Control. 2018;46 (5):581-583. doi: 10.1016/j.ajic.2017.11.011. PubMed PMID:29305276 .
  7. Fralick, M, Haj, R, Hirpara, D, Wong, K, Muller, M, Matukas, L et al.. Can a smartphone app improve medical trainees' knowledge of antibiotics?. Int J Med Educ. 2017;8 :416-420. doi: 10.5116/ijme.5a11.8422. PubMed PMID:29200402 PubMed Central PMC5768437.
  8. Cheng, MP, Bogoch, II, Green, K, Plevneshi, A, Rudnick, W, Shigayeva, A et al.. Factors Associated With 30-Day Mortality Rate in Respiratory Infections Caused by Streptococcus pneumoniae. Clin. Infect. Dis. 2018;66 (8):1282-1285. doi: 10.1093/cid/cix999. PubMed PMID:29140429 .
  9. Coleman, BL, Hassan, K, Green, K, Gubbay, JB, Katz, K, Mazzulli, T et al.. Pre-and post-pandemic trends in antiviral use in hospitalized patients with laboratory-confirmed influenza: 2004/05-2013/14, Toronto, Canada. Antiviral Res. 2017;140 :158-163. doi: 10.1016/j.antiviral.2017.01.025. PubMed PMID:28179155 .
  10. Ng, W, Faheem, A, McGeer, A, Simor, AE, Gelosia, A, Willey, BM et al.. Community- and Healthcare-Associated Methicillin-Resistant Staphylococcus aureus Strains: An Investigation Into Household Transmission, Risk Factors, and Environmental Contamination. Infect Control Hosp Epidemiol. 2017;38 (1):61-67. doi: 10.1017/ice.2016.245. PubMed PMID:27821194 .
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Affiliations & Other Activities

  • Medical Director, Infection Prevention and Control, St. Michael’s Hospital
  • Assistant Professor, Department of Medicine, University of Toronto