Mohammad Qadura

MD, PhD

Scientist

Biography

Dr. Mohammad Qadura is a Staff Surgeon in the Division of Vascular Surgery at St. Michael’s Hospital, a Scientist at the Keenan Research Centre for Biomedical Science of St. Michael’s Hospital, and an Assistant Professor at the University of Toronto. Dr. Qadura earned his doctorate in Pathology and Molecular Medicine at Queen’s University.

His interest in personalized medicine has led him to discover novel biomarkers for peripheral arterial disease. Specifically, Dr. Qadura’s research team has conducted in-depth studies to identify miRNA, proteins and metabolites that are strongly associated with peripheral arterial disease. Additionally, Dr. Qadura’s lab also investigates the personalization of anti-platelet and anti-coagulation therapy in patients with atherosclerotic vascular disease.

 Currently accepting graduate students.

Recent Publications

  1. Singh, S, Nguyen, HC, Ehsan, M, Michels, DCR, Singh, P, Qadura, M et al.. Pravastatin-induced changes in expression of long non-coding and coding RNAs in endothelial cells. Physiol Rep. 2021;9 (1):e14661. doi: 10.14814/phy2.14661. PubMed PMID:33369888 PubMed Central PMC7769171.
  2. Khan, H, Gallant, RC, Zamzam, A, Jain, S, Afxentiou, S, Syed, M et al.. Personalization of Aspirin Therapy Ex Vivo in Patients with Atherosclerosis Using Light Transmission Aggregometry. Diagnostics (Basel). 2020;10 (11):. doi: 10.3390/diagnostics10110871. PubMed PMID:33114560 PubMed Central PMC7693608.
  3. Nguyen, HC, Qadura, M, Singh, KK. Role of the Fatty Acid Binding Proteins in Cardiovascular Diseases: A Systematic Review. J Clin Med. 2020;9 (11):. doi: 10.3390/jcm9113390. PubMed PMID:33105856 PubMed Central PMC7690604.
  4. Khan, H, Gallant, R, Jain, S, Al-Omran, M, De Mestral, C, Greco, E et al.. Ticagrelor as an Alternative Antiplatelet Therapy in Cardiac Patients Non-Sensitive to Aspirin. Medicina (Kaunas). 2020;56 (10):. doi: 10.3390/medicina56100519. PubMed PMID:33023261 PubMed Central PMC7600331.
  5. Zamzam, A, Syed, MH, Greco, E, Wheatcroft, M, Jain, S, Khan, H et al.. Fatty Acid Binding Protein 4-A Circulating Protein Associated with Peripheral Arterial Disease in Diabetic Patients. J Clin Med. 2020;9 (9):. doi: 10.3390/jcm9092843. PubMed PMID:32887447 PubMed Central PMC7564356.
  6. Singh, S, Nguyen, H, Michels, D, Bazinet, H, Matkar, PN, Liu, Z et al.. BReast CAncer susceptibility gene 2 deficiency exacerbates oxidized LDL-induced DNA damage and endothelial apoptosis. Physiol Rep. 2020;8 (13):e14481. doi: 10.14814/phy2.14481. PubMed PMID:32638521 PubMed Central PMC7340845.
  7. Azab, SM, Zamzam, A, Syed, MH, Abdin, R, Qadura, M, Britz-McKibbin, P et al.. Serum Metabolic Signatures of Chronic Limb-Threatening Ischemia in Patients with Peripheral Artery Disease. J Clin Med. 2020;9 (6):. doi: 10.3390/jcm9061877. PubMed PMID:32560175 PubMed Central PMC7355749.
  8. Syed, MH, Zamzam, A, Valencia, J, Khan, H, Jain, S, Singh, KK et al.. MicroRNA Profile of Patients with Chronic Limb-Threatening Ischemia. Diagnostics (Basel). 2020;10 (4):. doi: 10.3390/diagnostics10040230. PubMed PMID:32316437 PubMed Central PMC7235988.
  9. Zamzam, A, Syed, MH, Rand, ML, Singh, K, Hussain, MA, Jain, S et al.. Altered coagulation profile in peripheral artery disease patients. Vascular. 2020;28 (4):368-377. doi: 10.1177/1708538120915997. PubMed PMID:32252612 .
  10. Singh, S, Adam, M, Matkar, PN, Bugyei-Twum, A, Desjardins, JF, Chen, HH et al.. Endothelial-specific Loss of IFT88 Promotes Endothelial-to-Mesenchymal Transition and Exacerbates Bleomycin-induced Pulmonary Fibrosis. Sci Rep. 2020;10 (1):4466. doi: 10.1038/s41598-020-61292-9. PubMed PMID:32161282 PubMed Central PMC7066128.
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Affiliations & Other Activities

  • Staff Surgeon, Division of Vascular Surgery, St. Michael’s Hospital
  • Associate Professor, University of Toronto
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