Muhammad Mamdani

MPH, MA, PharmD

Director, Li Ka Shing Centre for Healthcare Analytics Research and Training (CHART)


Dr. Mamdani is the Director of the Li Ka Shing Centre for Healthcare Analytics Research and Training (CHART) of the Li Ka Shing Knowledge Institute of St. Michael’s Hospital in Toronto. He is also Professor in the Leslie Dan Faculty of Pharmacy, the Department of Medicine of the Faculty of Medicine, and the Institute of Health Policy, Management and Evaluation of the Dalla Lana Faculty of Public Health. He is also adjunct Senior Scientist at the Institute for Clinical Evaluative Sciences (ICES). Dr. Mamdani also is a member of the Human Drug Advisory Panel of the Patented Medicine Prices Review Board (PMPRB) and is a co-Principal Investigator of the Ontario Drug Policy Research Network. In 2010, Dr. Mamdani was named among Canada’s Top 40 under 40. Prior to joining the Li Ka Shing Knowledge Institute and St. Michael’s Hospital, Dr. Mamdani was a Director of Outcomes Research at Pfizer Global Pharmaceuticals in New York. Dr. Mamdani’s research interests include pharmacoepidemiology, pharmacoeconomics, and drug policy. He has published approximately 350 research studies in peer-reviewed medical journals, including leading journals such as the New England Journal of Medicine, the Lancet, the Journal of the American Medical Association, the British Medical Journal, and Annals of Internal Medicine.

Dr. Mamdani obtained a Doctor of Pharmacy degree (PharmD) from the University of Michigan (Ann Arbor) in 1995 and subsequently completed a fellowship in pharmacoeconomics and outcomes research at the Detroit Medical Center in 1997. During his fellowship, Dr. Mamdani obtained a Master of Arts degree in Economics from Wayne State University in Detroit, Michigan. He then completed a Master of Public Health degree from Harvard University in 1998 with a concentration in quantitative methods, focusing on biostatistics and epidemiological principles.





Recent Publications

  1. Saposnik, G, Maurino, J, Sempere, AP, Terzaghi, MA, Ruff, CC, Mamdani, M et al.. Overcoming Therapeutic Inertia in Multiple Sclerosis Care: A Pilot Randomized Trial Applying the Traffic Light System in Medical Education. Front Neurol. 2017;8 :430. doi: 10.3389/fneur.2017.00430. PubMed PMID:28871238 PubMed Central PMC5567059.
  2. Gomes, T, Juurlink, DN, Mamdani, MM, Paterson, JM, van den Brink, W. Prevalence and characteristics of opioid-related deaths involving alcohol in Ontario, Canada. Drug Alcohol Depend. 2017;179 :416-423. doi: 10.1016/j.drugalcdep.2017.07.008. PubMed PMID:28867560 .
  3. Hussain, MA, Mamdani, M, Tu, JV, Saposnik, G, Salata, K, Bhatt, DL et al.. Association between operator specialty and outcomes after carotid artery revascularization. J. Vasc. Surg. 2017; :. doi: 10.1016/j.jvs.2017.05.123. PubMed PMID:28823867 .
  4. Alotaibi, NM, Ibrahim, GM, Wang, J, Guha, D, Mamdani, M, Schweizer, TA et al.. Neurosurgeon academic impact is associated with clinical outcomes after clipping of ruptured intracranial aneurysms. PLoS ONE. 2017;12 (7):e0181521. doi: 10.1371/journal.pone.0181521. PubMed PMID:28727832 PubMed Central PMC5519166.
  5. Voruganti, T, Grunfeld, E, Jamieson, T, Kurahashi, AM, Lokuge, B, Krzyzanowska, MK et al.. My Team of Care Study: A Pilot Randomized Controlled Trial of a Web-Based Communication Tool for Collaborative Care in Patients With Advanced Cancer. J. Med. Internet Res. 2017;19 (7):e219. doi: 10.2196/jmir.7421. PubMed PMID:28720558 PubMed Central PMC5539387.
  6. Aglipay, M, Birken, CS, Parkin, PC, Loeb, MB, Thorpe, K, Chen, Y et al.. Effect of High-Dose vs Standard-Dose Wintertime Vitamin D Supplementation on Viral Upper Respiratory Tract Infections in Young Healthy Children. JAMA. 2017;318 (3):245-254. doi: 10.1001/jama.2017.8708. PubMed PMID:28719693 .
  7. Livingston, MH, Mahant, S, Ratjen, F, Connolly, BL, Thorpe, K, Mamdani, M et al.. Intrapleural Dornase and Tissue Plasminogen Activator in pediatric empyema (DTPA): a study protocol for a randomized controlled trial. Trials. 2017;18 (1):293. doi: 10.1186/s13063-017-2026-0. PubMed PMID:28646887 PubMed Central PMC5482972.
  8. Ho, JM, Macdonald, EM, Luo, J, Gomes, T, Antoniou, T, Mamdani, MM et al.. Pregabalin and heart failure: A population-based study. Pharmacoepidemiol Drug Saf. 2017;26 (9):1087-1092. doi: 10.1002/pds.4239. PubMed PMID:28620909 .
  9. Quinn, KL, Macdonald, EM, Mamdani, MM, Diong, C, Juurlink, DN, Canadian Drug Safety and Effectiveness Research Network (CDSERN) et al.. Lipophilic Statins and the Risk of Intracranial Hemorrhage Following Ischemic Stroke: A Population-Based Study. Drug Saf. 2017; :. doi: 10.1007/s40264-017-0552-z. PubMed PMID:28620871 .
  10. Persaud, N, Lee, T, Ahmad, H, Li, W, Taglione, MS, Rajakulasingam, Y et al.. Protocol for a randomised controlled trial evaluating the effects of providing essential medicines at no charge: the Carefully seLected and Easily Accessible at No Charge Medicines (CLEAN Meds) trial. BMJ Open. 2017;7 (5):e015686. doi: 10.1136/bmjopen-2016-015686. PubMed PMID:28611089 .
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Affiliations & Other Activities

  • Scientist, Li Ka Shing Knowledge Institute, St. Michael’s Hospital
  • Professor, Institute of Health Policy, Management, and Evaluation, University of Toronto
  • Professor, Leslie Dan Faculty of Pharmacy, University of Toronto
  • Adjunct Professor, King Saud University Senior Adjunct
  • Scientist, Institute for Clinical Evaluative Sciences