Muhammad Mamdani

MPH, MA, PharmD

Director, Li Ka Shing Centre for Healthcare Analytics Research and Training (CHART)


Dr. Mamdani is the Director of the Li Ka Shing Centre for Healthcare Analytics Research and Training (CHART) of the Li Ka Shing Knowledge Institute of St. Michael’s Hospital in Toronto. He is also Professor in the Leslie Dan Faculty of Pharmacy, the Department of Medicine of the Faculty of Medicine, and the Institute of Health Policy, Management and Evaluation of the Dalla Lana Faculty of Public Health. He is also adjunct Senior Scientist at the Institute for Clinical Evaluative Sciences (ICES). Dr. Mamdani also is a member of the Human Drug Advisory Panel of the Patented Medicine Prices Review Board (PMPRB) and is a co-Principal Investigator of the Ontario Drug Policy Research Network. In 2010, Dr. Mamdani was named among Canada’s Top 40 under 40. Prior to joining the Li Ka Shing Knowledge Institute and St. Michael’s Hospital, Dr. Mamdani was a Director of Outcomes Research at Pfizer Global Pharmaceuticals in New York. Dr. Mamdani’s research interests include pharmacoepidemiology, pharmacoeconomics, and drug policy. He has published approximately 350 research studies in peer-reviewed medical journals, including leading journals such as the New England Journal of Medicine, the Lancet, the Journal of the American Medical Association, the British Medical Journal, and Annals of Internal Medicine.

Dr. Mamdani obtained a Doctor of Pharmacy degree (PharmD) from the University of Michigan (Ann Arbor) in 1995 and subsequently completed a fellowship in pharmacoeconomics and outcomes research at the Detroit Medical Center in 1997. During his fellowship, Dr. Mamdani obtained a Master of Arts degree in Economics from Wayne State University in Detroit, Michigan. He then completed a Master of Public Health degree from Harvard University in 1998 with a concentration in quantitative methods, focusing on biostatistics and epidemiological principles.





Recent Publications

  1. Elliott, J, Kelly, SE, Millar, AC, Peterson, J, Chen, L, Johnston, A et al.. Testosterone therapy in hypogonadal men: a systematic review and network meta-analysis. BMJ Open. 2017;7 (11):e015284. doi: 10.1136/bmjopen-2016-015284. PubMed PMID:29150464 .
  2. So, M, Mamdani, M, Morris, A, Lau, T, Broady, R, Deotare, U et al.. Effect of an Antimicrobial Stewardship Programme on Antimicrobial Utilisation and Costs in Patients with Leukaemia: A Retrospective Interventional Controlled Study. Clin. Microbiol. Infect. 2017; :. doi: 10.1016/j.cmi.2017.11.009. PubMed PMID:29138099 .
  3. Alotaibi, NM, Wang, JZ, Pasarikovski, CR, Guha, D, Al-Mufti, F, Mamdani, M et al.. Management of raised intracranial pressure in aneurysmal subarachnoid hemorrhage: time for a consensus?. Neurosurg Focus. 2017;43 (5):E13. doi: 10.3171/2017.7.FOCUS17426. PubMed PMID:29088956 .
  4. Tadrous, M, Khuu, W, Lebovic, G, Stanbrook, MB, Martins, D, Paterson, JM et al.. Real-world health care utilization and effectiveness of omalizumab for the treatment of severe asthma. Ann. Allergy Asthma Immunol. 2017; :. doi: 10.1016/j.anai.2017.08.016. PubMed PMID:28986124 .
  5. Gomes, T, Juurlink, DN, Antoniou, T, Mamdani, MM, Paterson, JM, van den Brink, W et al.. Gabapentin, opioids, and the risk of opioid-related death: A population-based nested case-control study. PLoS Med. 2017;14 (10):e1002396. doi: 10.1371/journal.pmed.1002396. PubMed PMID:28972983 PubMed Central PMC5626029.
  6. Lapointe-Shaw, L, Mamdani, M, Luo, J, Austin, PC, Ivers, NM, Redelmeier, DA et al.. Effectiveness of a financial incentive to physicians for timely follow-up after hospital discharge: a population-based time series analysis. CMAJ. 2017;189 (39):E1224-E1229. doi: 10.1503/cmaj.170092. PubMed PMID:28970260 PubMed Central PMC5628034.
  7. Tan, NS, Ali, SH, Lebovic, G, Mamdani, M, Laupacis, A, Yan, AT et al.. Temporal Trends in Use of Composite End Points in Major Cardiovascular Randomized Clinical Trials in Prominent Medical Journals. Circ Cardiovasc Qual Outcomes. 2017;10 (10):. doi: 10.1161/CIRCOUTCOMES.117.003753. PubMed PMID:28954803 .
  8. Saposnik, G, Maurino, J, Sempere, AP, Terzaghi, MA, Ruff, CC, Mamdani, M et al.. Overcoming Therapeutic Inertia in Multiple Sclerosis Care: A Pilot Randomized Trial Applying the Traffic Light System in Medical Education. Front Neurol. 2017;8 :430. doi: 10.3389/fneur.2017.00430. PubMed PMID:28871238 PubMed Central PMC5567059.
  9. Gomes, T, Juurlink, DN, Mamdani, MM, Paterson, JM, van den Brink, W. Prevalence and characteristics of opioid-related deaths involving alcohol in Ontario, Canada. Drug Alcohol Depend. 2017;179 :416-423. doi: 10.1016/j.drugalcdep.2017.07.008. PubMed PMID:28867560 .
  10. Hussain, MA, Mamdani, M, Tu, JV, Saposnik, G, Salata, K, Bhatt, DL et al.. Association between operator specialty and outcomes after carotid artery revascularization. J. Vasc. Surg. 2017; :. doi: 10.1016/j.jvs.2017.05.123. PubMed PMID:28823867 .
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Affiliations & Other Activities

  • Scientist, Li Ka Shing Knowledge Institute, St. Michael’s Hospital
  • Professor, Institute of Health Policy, Management, and Evaluation, University of Toronto
  • Professor, Leslie Dan Faculty of Pharmacy, University of Toronto
  • Adjunct Professor, King Saud University Senior Adjunct
  • Scientist, Institute for Clinical Evaluative Sciences