Muhammad Mamdani

MPH, MA, PharmD

Director, Li Ka Shing Centre for Healthcare Analytics Research and Training (CHART)


Dr. Mamdani is the Director of the Li Ka Shing Centre for Healthcare Analytics Research and Training (CHART) of the Li Ka Shing Knowledge Institute of St. Michael’s Hospital in Toronto. He is also Professor in the Leslie Dan Faculty of Pharmacy, the Department of Medicine of the Faculty of Medicine, and the Institute of Health Policy, Management and Evaluation of the Dalla Lana Faculty of Public Health. He is also adjunct Senior Scientist at the Institute for Clinical Evaluative Sciences (ICES). Dr. Mamdani also is a member of the Human Drug Advisory Panel of the Patented Medicine Prices Review Board (PMPRB) and is a co-Principal Investigator of the Ontario Drug Policy Research Network. In 2010, Dr. Mamdani was named among Canada’s Top 40 under 40. Prior to joining the Li Ka Shing Knowledge Institute and St. Michael’s Hospital, Dr. Mamdani was a Director of Outcomes Research at Pfizer Global Pharmaceuticals in New York. Dr. Mamdani’s research interests include pharmacoepidemiology, pharmacoeconomics, and drug policy. He has published approximately 350 research studies in peer-reviewed medical journals, including leading journals such as the New England Journal of Medicine, the Lancet, the Journal of the American Medical Association, the British Medical Journal, and Annals of Internal Medicine.

Dr. Mamdani obtained a Doctor of Pharmacy degree (PharmD) from the University of Michigan (Ann Arbor) in 1995 and subsequently completed a fellowship in pharmacoeconomics and outcomes research at the Detroit Medical Center in 1997. During his fellowship, Dr. Mamdani obtained a Master of Arts degree in Economics from Wayne State University in Detroit, Michigan. He then completed a Master of Public Health degree from Harvard University in 1998 with a concentration in quantitative methods, focusing on biostatistics and epidemiological principles.

Please note: Dr. Mamdani is not taking any summer students in 2018.




Recent Publications

  1. Salata, K, Hussain, MA, De Mestral, C, Greco, E, Mamdani, M, Tu, JV et al.. Validation of abdominal aortic aneurysm repair codes in Ontario administrative data. Clin Invest Med. 2018;41 (3):E148-E155. . PubMed PMID:30315751 .
  2. Black, CD, McCarthy, L, Gomes, T, Mamdani, M, Juurlink, D, Tadrous, M et al.. Interprovincial Variation of Psychotropic Prescriptions Dispensed to Older Canadian Adults. Can Geriatr J. 2018;21 (3):269-273. doi: 10.5770/cgj.21.307. PubMed PMID:30271512 PubMed Central PMC6136906.
  3. Gomes, T, Khuu, W, Martins, D, Tadrous, M, Mamdani, MM, Paterson, JM et al.. Contributions of prescribed and non-prescribed opioids to opioid related deaths: population based cohort study in Ontario, Canada. BMJ. 2018;362 :k3207. . PubMed PMID:30158106 PubMed Central PMC6113771.
  4. Gomes, T, Greaves, S, van den Brink, W, Antoniou, T, Mamdani, MM, Paterson, JM et al.. Pregabalin and the Risk for Opioid-Related Death: A Nested Case-Control Study. Ann. Intern. Med. 2018; :. doi: 10.7326/M18-1136. PubMed PMID:30140853 .
  5. Gomes, T, Khuu, W, Craiovan, D, Martins, D, Hunt, J, Lee, K et al.. Comparing the contribution of prescribed opioids to opioid-related hospitalizations across Canada: A multi-jurisdictional cross-sectional study. Drug Alcohol Depend. 2018;191 :86-90. doi: 10.1016/j.drugalcdep.2018.06.028. PubMed PMID:30096638 .
  6. Persaud, N, Laupacis, A, Azarpazhooh, A, Birken, C, Hoch, JS, Isaranuwatchai, W et al.. Xylitol for the prevention of acute otitis media episodes in children aged 2-4 years: protocol for a pragmatic randomised controlled trial. BMJ Open. 2018;8 (8):e020941. doi: 10.1136/bmjopen-2017-020941. PubMed PMID:30082349 PubMed Central PMC6078241.
  7. Wijeysundera, DN, Pearse, RM, Shulman, MA, Abbott, TEF, Torres, E, Ambosta, A et al.. Assessment of functional capacity before major non-cardiac surgery: an international, prospective cohort study. Lancet. 2018;391 (10140):2631-2640. doi: 10.1016/S0140-6736(18)31131-0. PubMed PMID:30070222 .
  8. Saposnik, G, Tobler, PN, Caceres, F, Terzaghi, MA, Ruff, C, Maurino, J et al.. Usability of an Educational Intervention to Overcome Therapeutic Inertia in Multiple Sclerosis Care. Front Neurol. 2018;9 :522. doi: 10.3389/fneur.2018.00522. PubMed PMID:30042720 PubMed Central PMC6048250.
  9. Finkelstein, Y, Macdonald, EM, Li, P, Mamdani, MM, Gomes, T, Juurlink, DN et al.. Second-generation anti-depressants and risk of new-onset seizures in the elderly. Clin Toxicol (Phila). 2018; :1-6. doi: 10.1080/15563650.2018.1483025. PubMed PMID:29989445 .
  10. Verma, AA, Khuu, W, Tadrous, M, Gomes, T, Mamdani, MM. Fixed-dose combination antihypertensive medications, adherence, and clinical outcomes: A population-based retrospective cohort study. PLoS Med. 2018;15 (6):e1002584. doi: 10.1371/journal.pmed.1002584. PubMed PMID:29889841 PubMed Central PMC5995349.
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Affiliations & Other Activities

  • Scientist, Li Ka Shing Knowledge Institute, St. Michael’s Hospital
  • Professor, Institute of Health Policy, Management, and Evaluation, University of Toronto
  • Professor, Leslie Dan Faculty of Pharmacy, University of Toronto
  • Adjunct Professor, King Saud University Senior Adjunct
  • Scientist, Institute for Clinical Evaluative Sciences