Muhammad Mamdani

MPH, MA, PharmD

Director, Li Ka Shing Centre for Healthcare Analytics Research and Training (CHART)


Dr. Mamdani is the Director of the Li Ka Shing Centre for Healthcare Analytics Research and Training (CHART) of the Li Ka Shing Knowledge Institute of St. Michael’s Hospital in Toronto. He is also Professor in the Leslie Dan Faculty of Pharmacy, the Department of Medicine of the Faculty of Medicine, and the Institute of Health Policy, Management and Evaluation of the Dalla Lana Faculty of Public Health. He is also adjunct Senior Scientist at the Institute for Clinical Evaluative Sciences (ICES). Dr. Mamdani also is a member of the Human Drug Advisory Panel of the Patented Medicine Prices Review Board (PMPRB) and is a co-Principal Investigator of the Ontario Drug Policy Research Network. In 2010, Dr. Mamdani was named among Canada’s Top 40 under 40. Prior to joining the Li Ka Shing Knowledge Institute and St. Michael’s Hospital, Dr. Mamdani was a Director of Outcomes Research at Pfizer Global Pharmaceuticals in New York. Dr. Mamdani’s research interests include pharmacoepidemiology, pharmacoeconomics, and drug policy. He has published approximately 350 research studies in peer-reviewed medical journals, including leading journals such as the New England Journal of Medicine, the Lancet, the Journal of the American Medical Association, the British Medical Journal, and Annals of Internal Medicine.

Dr. Mamdani obtained a Doctor of Pharmacy degree (PharmD) from the University of Michigan (Ann Arbor) in 1995 and subsequently completed a fellowship in pharmacoeconomics and outcomes research at the Detroit Medical Center in 1997. During his fellowship, Dr. Mamdani obtained a Master of Arts degree in Economics from Wayne State University in Detroit, Michigan. He then completed a Master of Public Health degree from Harvard University in 1998 with a concentration in quantitative methods, focusing on biostatistics and epidemiological principles.

Please note: Dr. Mamdani is not taking any summer students.




Recent Publications

  1. Laba, TL, Cheng, L, Worthington, HC, McGrail, KM, Chan, FKI, Mamdani, M et al.. What happens to drug use and expenditure when cost sharing is completely removed? Evidence from a Canadian provincial public drug plan. Health Policy. 2020; :. doi: 10.1016/j.healthpol.2020.05.001. PubMed PMID:32553741 .
  2. Bisson, DA, Flaherty, ML, Shatil, AS, Gladstone, D, Dowlatshahi, D, Carrozzella, J et al.. Original and Modified Graeb Score Correlation With Intraventricular Hemorrhage and Clinical Outcome Prediction in Hyperacute Intracranial Hemorrhage. Stroke. 2020;51 (6):1696-1702. doi: 10.1161/STROKEAHA.120.029040. PubMed PMID:32390552 .
  3. Tadrous, M, Martins, D, Mamdani, MM, Gomes, T. Characteristics of high-drug-cost beneficiaries of public drug plans in 9 Canadian provinces: a cross-sectional analysis. CMAJ Open. ;8 (2):E297-E303. doi: 10.9778/cmajo.20190231. PubMed PMID:32345708 PubMed Central PMC7207026.
  4. Mazereeuw, G, Gomes, T, Macdonald, EM, Greaves, S, Li, P, Mamdani, MM et al.. Oxycodone, Hydromorphone, and the Risk of Suicide: A Retrospective Population-Based Case-Control Study. Drug Saf. 2020; :. doi: 10.1007/s40264-020-00924-5. PubMed PMID:32328907 .
  5. Daneman, N, Cheng, Y, Gomes, T, Guan, J, Mamdani, MM, Saxena, FE et al.. Metronidazole-associated Neurologic Events: A Nested-Case Control Study. Clin. Infect. Dis. 2020; :. doi: 10.1093/cid/ciaa395. PubMed PMID:32303736 .
  6. Verma, AA, Guo, Y, Jung, HY, Laupacis, A, Mamdani, M, Detsky, AS et al.. Physician-level variation in clinical outcomes and resource use in inpatient general internal medicine: an observational study. BMJ Qual Saf. 2020; :. doi: 10.1136/bmjqs-2019-010425. PubMed PMID:32220936 .
  7. Salata, K, Abdallah, FW, Hussain, MA, de Mestral, C, Greco, E, Aljabri, B et al.. Short-term outcomes of combined neuraxial and general anaesthesia versus general anaesthesia alone for elective open abdominal aortic aneurysm repair: retrospective population-based cohort study. Br J Anaesth. 2020;124 (5):544-552. doi: 10.1016/j.bja.2020.01.018. PubMed PMID:32216957 .
  8. Li, X, Keown-Stoneman, CDG, Lebovic, G, Omand, JA, Adeli, K, Hamilton, JK et al.. The association between body mass index trajectories and cardiometabolic risk in young children. Pediatr Obes. 2020; :e12633. doi: 10.1111/ijpo.12633. PubMed PMID:32181602 .
  9. Salata, K, Hussain, MA, de Mestral, C, Greco, E, Awartani, H, Aljabri, BA et al.. Population-based long-term outcomes of open versus endovascular aortic repair of ruptured abdominal aortic aneurysms. J. Vasc. Surg. 2020;71 (6):1867-1878.e8. doi: 10.1016/j.jvs.2019.06.212. PubMed PMID:32085959 .
  10. Livingston, MH, Mahant, S, Connolly, B, MacLusky, I, Laberge, S, Giglia, L et al.. Effectiveness of Intrapleural Tissue Plasminogen Activator and Dornase Alfa vs Tissue Plasminogen Activator Alone in Children with Pleural Empyema: A Randomized Clinical Trial. JAMA Pediatr. 2020; :. doi: 10.1001/jamapediatrics.2019.5863. PubMed PMID:32011642 PubMed Central PMC7042898.
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Affiliations & Other Activities

  • Scientist, Li Ka Shing Knowledge Institute, St. Michael’s Hospital
  • Professor, Institute of Health Policy, Management, and Evaluation, University of Toronto
  • Professor, Leslie Dan Faculty of Pharmacy, University of Toronto
  • Adjunct Professor, King Saud University Senior Adjunct
  • Scientist, Institute for Clinical Evaluative Sciences