Neeru Gupta


Scientist, Keenan Research Centre for Biomedical Science

Tel: 416-864-5444
LinkedIn: Neeru Gupta

Research Programs


Research Interests

Retinal disease, glaucoma, degeneration of vision pathways, neuroprotection and pharmacological treatment strategies, intraocular pressure regulation, the role of the lymphatic circulation in the eye, neuroimaging and clinical trials

Research Activities

I have a longstanding and broad interest in vision science, covering a variety of topics. These include retinal disease, the neuropharmacology of glaucoma, glaucoma as a neurodegenerative disease, the regulation of intraocular pressure, and the lymphatic circulation. Studies in the laboratory support and complement ongoing clinical studies and trials.

Recent Publications

  1. Ozturker, ZK, Munro, K, Gupta, N. Optic disc hemorrhages in glaucoma and common clinical features. Can. J. Ophthalmol. 2017;52 (6):583-591. doi: 10.1016/j.jcjo.2017.04.011. PubMed PMID:29217027 .
  2. Chan, SWS, Khattak, S, Yücel, N, Gupta, N, Yücel, YH. A decade of surgical eye removals in Ontario: a clinical-pathological study. Can. J. Ophthalmol. 2017;52 (5):486-493. doi: 10.1016/j.jcjo.2017.02.025. PubMed PMID:28985809 .
  3. Mathieu, E, Gupta, N, Ahari, A, Zhou, X, Hanna, J, Yücel, YH et al.. Evidence for Cerebrospinal Fluid Entry Into the Optic Nerve via a Glymphatic Pathway. Invest. Ophthalmol. Vis. Sci. 2017;58 (11):4784-4791. doi: 10.1167/iovs.17-22290. PubMed PMID:28973323 .
  4. Le, R, Yucel, N, Khattak, S, Yucel, YH, Prud'homme, GJ, Gupta, N et al.. Current indications and surgical approaches to corneal transplants at the University of Toronto: A clinical-pathological study. Can. J. Ophthalmol. 2017;52 (1):74-79. doi: 10.1016/j.jcjo.2016.07.005. PubMed PMID:28237153 .
  5. Le, R, Berger, AR, Gupta, N. Long-term Follow-up of a Case of Gold Shunt Surgery for Refractory Silicone Oil-induced Glaucoma. J. Glaucoma. 2016;25 (8):e734-7. doi: 10.1097/IJG.0000000000000450. PubMed PMID:27253968 PubMed Central PMC4972476.
  6. Le, R, Gupta, N. Gold shunt for refractory advanced low-tension glaucoma with spared central acuity. Int Med Case Rep J. 2016;9 :69-72. doi: 10.2147/IMCRJ.S93849. PubMed PMID:27051320 PubMed Central PMC4807951.
  7. McKetton, L, Williams, J, Viviano, JD, Yücel, YH, Gupta, N, Schneider, KA et al.. High-resolution Structural Magnetic Resonance Imaging of the Human Subcortex In Vivo and Postmortem. J Vis Exp. 2015; (106):e53309. doi: 10.3791/53309. PubMed PMID:26779880 PubMed Central PMC4780869.
  8. Yucel, Y, Gupta, N. Lymphatic drainage from the eye: A new target for therapy. Prog. Brain Res. 2015;220 :185-98. doi: 10.1016/bs.pbr.2015.07.028. PubMed PMID:26497791 .
  9. Yucel, YH, Gupta, N. A framework to explore the visual brain in glaucoma with lessons from models and man. Exp. Eye Res. 2015;141 :171-8. doi: 10.1016/j.exer.2015.07.004. PubMed PMID:26169795 .
  10. Gupta, N, Kocur, I. Chronic eye disease and the WHO Universal Eye Health Global Action Plan 2014-2019. Can. J. Ophthalmol. 2014;49 (5):403-5. doi: 10.1016/j.jcjo.2014.08.014. PubMed PMID:25284093 .
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Affiliations & Other Activities

  • Scientist, Li Ka Shing Knowledge Institute, St. Michael’s Hospital
  • Director, Glaucoma Unit, Department of Ophthalmology, St. Michael’s Hospital / University of Toronto
  • Co-Founder and CEO, Human Eye Biobank for Research, St.Michael’s
  • Professor, Ophthalmology & Vision Sciences, Faculty of Medicine, University of Toronto
  • Professor, Laboratory Medicine & Pathobiology, University of Toronto
  • Member, Institute of Medical Science, University of Toronto
  • Member, Graduate Studies, Department of Laboratory Medicine & Pathobiology, University of Toronto
  • Chief of Glaucoma, University of Toronto
  • Immediate Past-President, Canadian Glaucoma Society
  • Chair, Advisory Board to the International Council of Ophthalmology
  • Board of Directors, International Council of Ophthalmology
  • Diabetic Eye Care Task Force, International Council of Ophthalmology
  • Chair, Glaucoma Task Force, International Council of Ophthalmology
  • Scientific Advisory Board, Glaucoma Foundation, New York, USA
  • Editorial Board, Investigative Ophthalmology and Vision Science
  • Editor, Translational Vision Science & Technology, Canadian Journal of Ophthalmology
  • Editorial Board, Asia-Pacific Journal of Ophthalmology
  • Editorial Board, Eye and Brain
  • Editorial Board, International Glaucoma Review