Orla Smith




My main areas of research interest are decision-making and psychological outcomes in family members of critically ill patients.

Recent Publications

  1. Rose, L, Sutt, AL, Amaral, AC, Fergusson, DA, Smith, OM, Dale, CM et al.. Interventions to enable communication for adult patients requiring an artificial airway with or without mechanical ventilator support. Cochrane Database Syst Rev. 2021;10 :CD013379. doi: 10.1002/14651858.CD013379.pub2. PubMed PMID:34637143 PubMed Central PMC8507432.
  2. Dale, CM, Rose, L, Carbone, S, Pinto, R, Smith, OM, Burry, L et al.. Effect of oral chlorhexidine de-adoption and implementation of an oral care bundle on mortality for mechanically ventilated patients in the intensive care unit (CHORAL): a multi-center stepped wedge cluster-randomized controlled trial. Intensive Care Med. 2021; :. doi: 10.1007/s00134-021-06475-2. PubMed PMID:34609548 PubMed Central PMC8490143.
  3. Takaoka, A, Vanstone, M, Neville, TH, Goksoyr, S, Swinton, M, Clarke, FJ et al.. Family and Clinician Experiences of Sympathy Cards in the 3 Wishes Project. Am J Crit Care. 2020;29 (6):422-428. doi: 10.4037/ajcc2020733. PubMed PMID:33130860 .
  4. STARRT-AKI Investigators, Canadian Critical Care Trials Group, Australian and New Zealand Intensive Care Society Clinical Trials Group, United Kingdom Critical Care Research Group, Canadian Nephrology Trials Network, Irish Critical Care Trials Group et al.. Timing of Initiation of Renal-Replacement Therapy in Acute Kidney Injury. N Engl J Med. 2020;383 (3):240-251. doi: 10.1056/NEJMoa2000741. PubMed PMID:32668114 .
  5. Smith, OM, Metcalfe, K, Puts, M, McDonald, E, Sue-Chee, S, Friedrich, JO et al.. Role Incongruence and Psychological Stress Symptoms in Substitute Decision Makers of Intensive Care Patients. Am J Crit Care. 2020;29 (4):301-310. doi: 10.4037/ajcc2020307. PubMed PMID:32607568 .
  6. Vanstone, M, Neville, TH, Swinton, ME, Sadik, M, Clarke, FJ, LeBlanc, A et al.. Expanding the 3 Wishes Project for compassionate end-of-life care: a qualitative evaluation of local adaptations. BMC Palliat Care. 2020;19 (1):93. doi: 10.1186/s12904-020-00601-5. PubMed PMID:32605623 PubMed Central PMC7325646.
  7. Neville, TH, Clarke, F, Takaoka, A, Sadik, M, Vanstone, M, Phung, P et al.. Keepsakes at the End of Life. J Pain Symptom Manage. 2020;60 (5):941-947. doi: 10.1016/j.jpainsymman.2020.06.011. PubMed PMID:32574658 .
  8. Takaoka, A, Honarmand, K, Vanstone, M, Tam, B, Smith, OM, Baker, A et al.. Organ Donation at the End of Life: Experiences From the 3 Wishes Project. J Intensive Care Med. 2021;36 (4):404-412. doi: 10.1177/0885066619900125. PubMed PMID:31960743 .
  9. Dale, CM, Rose, L, Carbone, S, Smith, OM, Burry, L, Fan, E et al.. Protocol for a multi-centered, stepped wedge, cluster randomized controlled trial of the de-adoption of oral chlorhexidine prophylaxis and implementation of an oral care bundle for mechanically ventilated critically ill patients: the CHORAL study. Trials. 2019;20 (1):603. doi: 10.1186/s13063-019-3673-0. PubMed PMID:31651364 PubMed Central PMC6814100.
  10. Rose, L, Istanboulian, L, Smith, OM, Silencieux, S, Cuthbertson, BH, Amaral, ACK et al.. Feasibility of the electrolarynx for enabling communication in the chronically critically ill: The EECCHO study. J Crit Care. 2018;47 :109-113. doi: 10.1016/j.jcrc.2018.06.013. PubMed PMID:29945066 .
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Affiliations & Other Activities

  • Research Manager, Critical Care, St. Michael’s Hospital