Orla Smith


Associate Scientist, Li Ka Shing Knowledge Institute


Please note: Dr. Smith is not taking any summer students in 2019.

My main areas of research interest are decision-making and evidence-based practice in critical care. I am currently conducting a multi-centre study of decision-making preferences and psychological outcomes in family members of critically ill patients funded by Sigma Theta Tau International (STTI). Our research group has recently commenced a program of research to better understand the relationship between homelessness and intensive care unit utilization. I am also currently involved in the development of two national evidence based guidelines related to the prevention and management of ventilator associated pneumonia and the implementation of therapeutic hypothermia post-cardiac arrest.


Recent Publications

  1. Rose, L, Istanboulian, L, Smith, OM, Silencieux, S, Cuthbertson, BH, Amaral, ACK et al.. Feasibility of the electrolarynx for enabling communication in the chronically critically ill: The EECCHO study. J Crit Care. 2018;47 :109-113. doi: 10.1016/j.jcrc.2018.06.013. PubMed PMID:29945066 .
  2. Smith, OM, Chant, C, Burns, KEA, Kaur, M, Ashraf, S, DosSantos, CC et al.. Characteristics, clinical course, and outcomes of homeless and non-homeless patients admitted to ICU: A retrospective cohort study. PLoS ONE. 2017;12 (6):e0179207. doi: 10.1371/journal.pone.0179207. PubMed PMID:28604792 PubMed Central PMC5467852.
  3. Rose, L, Dale, C, Smith, OM, Burry, L, Enright, G, Fergusson, D et al.. A mixed-methods systematic review protocol to examine the use of physical restraint with critically ill adults and strategies for minimizing their use. Syst Rev. 2016;5 (1):194. doi: 10.1186/s13643-016-0372-8. PubMed PMID:27871314 PubMed Central PMC5117692.
  4. Burns, KE, Prats, CJ, Maione, M, Lanceta, M, Zubrinich, C, Jeffs, L et al.. The Experience of Surrogate Decision Makers on Being Approached for Consent for Patient Participation in Research. A Multicenter Study. Ann Am Thorac Soc. 2017;14 (2):238-245. doi: 10.1513/AnnalsATS.201606-425OC. PubMed PMID:27849142 .
  5. Brooks, SC, Scales, DC, Pinto, R, Dainty, KN, Racz, EM, Gaudio, M et al.. The Postcardiac Arrest Consult Team: Impact on Hospital Care Processes for Out-of-Hospital Cardiac Arrest Patients. Crit. Care Med. 2016;44 (11):2037-2044. doi: 10.1097/CCM.0000000000001863. PubMed PMID:27509389 .
  6. Smith, OM, Dale, C, Mehta, S, Pinto, R, Rose, L. Nurse Research Experiences and Attitudes Toward the Conduct of Intensive Care Research: A Questionnaire Study. Crit. Care Med. 2016;44 (1):153-61. doi: 10.1097/CCM.0000000000001386. PubMed PMID:26672924 .
  7. Rewa, O, Wald, R, Adhikari, NK, Hladunewich, M, Lapinsky, S, Muscedere, J et al.. Whole-blood neutrophil gelatinase-associated lipocalin to predict adverse events in acute kidney injury: A prospective observational cohort study. J Crit Care. 2015;30 (6):1359-64. doi: 10.1016/j.jcrc.2015.08.019. PubMed PMID:26421697 .
  8. Howes, D, Gray, SH, Brooks, SC, Boyd, JG, Djogovic, D, Golan, E et al.. Canadian Guidelines for the use of targeted temperature management (therapeutic hypothermia) after cardiac arrest: A joint statement from The Canadian Critical Care Society (CCCS), Canadian Neurocritical Care Society (CNCCS), and the Canadian Critical Care Trials Group (CCCTG). Resuscitation. 2016;98 :48-63. doi: 10.1016/j.resuscitation.2015.07.052. PubMed PMID:26417702 .
  9. Wald, R, Adhikari, NK, Smith, OM, Weir, MA, Pope, K, Cohen, A et al.. Comparison of standard and accelerated initiation of renal replacement therapy in acute kidney injury. Kidney Int. 2015;88 (4):897-904. doi: 10.1038/ki.2015.184. PubMed PMID:26154928 .
  10. Burns, KE, Rizvi, L, Smith, OM, Lee, Y, Lee, J, Wang, M et al.. Is there a role for physician involvement in introducing research to surrogate decision makers in the intensive care unit? (The Approach trial: a pilot mixed methods study). Intensive Care Med. 2015;41 (1):58-67. doi: 10.1007/s00134-014-3558-3. PubMed PMID:25491659 .
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Affiliations & Other Activities

  • Research Manager, Critical Care, St. Michael’s Hospital