Paul Dorian

MD, CM, MSc

Scientist, Keenan Research Centre for Biomedical Science

Research Programs

Biography

Dr. Paul Dorian is the Department Director, Division of Cardiology, University of Toronto and Staff Cardiac Electrophysiologist at St. Michael’s Hospital. He is Professor of Medicine in the Division of Cardiology and in the Division of Clinical Pharmacology at the University of Toronto, and a Staff Scientist at the Li Ka Shing Knowledge Institute.

Dr. Dorian received his medical degree from McGill University in Montreal in 1976. He continued training in Internal Medicine and Cardiology at the University of Toronto, and received certification by the Royal College of Physicians and Surgeons of Canada in Internal Medicine in 1983 and certification in Cardiology in 1984. He completed training in Clinical Pharmacology at the University of Toronto in 1982, and received an MSc in Pharmacology from the University of Toronto in 1982. From 1983 to 1985, he completed a Fellowship in Cardiac Electrophysiology at Stanford University Medical Centre in California.

His research interests include basic science research in advanced cardiac life support and atrial fibrillation, the clinical pharmacology of antiarrhythmic drugs, and clinical research on implanted devices, antiarrhythmic drugs, and quality of life in patients with arrhythmias.

He is the immediate Past-President of the Canadian Heart Rhythm Society, Chairman of the Cardiac Arrest Committee, St. Michael’s Hospital, Co-Principle Investigator on the National Institutes of Health funded Resuscitation Outcomes Consortium, and serves on the steering committee of multiple multicenter clinical trials in arrhythmia care. He is the Chair of the Canadian Cardiovascular Society Quality Committee.

He has published over 350 peer reviewed papers and is Associate Editor of the textbook Electrophysiological Disorders of the Heart.

Recent Publications

  1. Landry, CH, Allan, KS, Connelly, KA, Cunningham, K, Morrison, LJ, Dorian, P et al.. Sudden Cardiac Arrest during Participation in Competitive Sports. N. Engl. J. Med. 2017;377 (20):1943-1953. doi: 10.1056/NEJMoa1615710. PubMed PMID:29141175 .
  2. Dorian, P, Kells, C. Federal leadership needed to realize national data set for cardiovascular care. CMAJ. 2017;189 (41):E1294. doi: 10.1503/cmaj.733412. PubMed PMID:29038324 PubMed Central PMC5647171.
  3. Kudenchuk, PJ, Leroux, BG, Daya, M, Rea, T, Vaillancourt, C, Morrison, LJ et al.. Antiarrhythmic Drugs for Non-Shockable-Turned-Shockable Out-of-Hospital Cardiac Arrest: The Amiodarone, Lidocaine or Placebo Study (ALPS). Circulation. 2017; :. doi: 10.1161/CIRCULATIONAHA.117.028624. PubMed PMID:28904070 .
  4. Friedman, DJ, Al-Khatib, SM, Zeitler, EP, Han, J, Bardy, GH, Poole, JE et al.. New York Heart Association class and the survival benefit from primary prevention implantable cardioverter defibrillators: A pooled analysis of 4 randomized controlled trials. Am. Heart J. 2017;191 :21-29. doi: 10.1016/j.ahj.2017.06.002. PubMed PMID:28888266 PubMed Central PMC5657554.
  5. Haldar, SK, Magtibay, K, Porta-Sanchez, A, Massé, S, Mitsakakis, N, Lai, PFH et al.. Resolving Bipolar Electrogram Voltages During Atrial Fibrillation Using Omnipolar Mapping. Circ Arrhythm Electrophysiol. 2017;10 (9):. doi: 10.1161/CIRCEP.117.005018. PubMed PMID:28887362 .
  6. Ho, EC, Cheskes, S, Angaran, P, Morrison, LJ, Aves, T, Zhan, C et al.. Implantable Cardioverter Defibrillator Implantation Rates After Out of Hospital Cardiac Arrest: Are the Rates Guideline-Concordant?. Can J Cardiol. 2017;33 (10):1266-1273. doi: 10.1016/j.cjca.2017.05.013. PubMed PMID:28867265 .
  7. Allan, KS, Henry, S, Aves, T, Banfield, L, Victor, JC, Dorian, P et al.. Comparison of health-related quality of life in patients with atrial fibrillation treated with catheter ablation or antiarrhythmic drug therapy: a systematic review and meta-analysis protocol. BMJ Open. 2017;7 (8):e017577. doi: 10.1136/bmjopen-2017-017577. PubMed PMID:28827273 .
  8. Kawano, T, Grunau, B, Scheuermeyer, FX, Gibo, K, Dick, W, Fordyce, CB et al.. Prehospital sodium bicarbonate use could worsen long term survival with favorable neurological recovery among patients with out-of-hospital cardiac arrest. Resuscitation. 2017;119 :63-69. doi: 10.1016/j.resuscitation.2017.08.008. PubMed PMID:28802878 .
  9. Zeitler, EP, Al-Khatib, SM, Friedman, DJ, Han, JY, Poole, JE, Bardy, GH et al.. Predicting appropriate shocks in patients with heart failure: Patient level meta-analysis from SCD-HeFT and MADIT II. J. Cardiovasc. Electrophysiol. 2017;28 (11):1345-1351. doi: 10.1111/jce.13307. PubMed PMID:28744959 PubMed Central PMC5693305.
  10. Bhatia, RS, Bouck, Z, Ivers, NM, Mecredy, G, Singh, J, Pendrith, C et al.. Electrocardiograms in Low-Risk Patients Undergoing an Annual Health Examination. JAMA Intern Med. 2017;177 (9):1326-1333. doi: 10.1001/jamainternmed.2017.2649. PubMed PMID:28692719 .
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Affiliations & Other Activities

  • Staff Cardiac Electrophysiologist, St. Michael’s Hospital
  • Professor, Medicine and Cardiology, St. Michael’s Hospital, University of Toronto
  • Director, Division of Cardiology, University of Toronto
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