Samir Gupta


Associate Scientist, Li Ka Shing Knowledge Institute

Research Programs


Samir Gupta is a clinician-scientist at the Li Ka Shing Knowledge Institute of St. Michael’s Hospital and an Assistant Professor in the Department of Medicine at the University of Toronto. He is also a Staff Respirologist in the Division of Respirology at St. Michael’s Hospital. He completed his Master’s degree in Clinical Epidemiology at the University of Toronto, followed by a fellowship in Knowledge Translation Research. His main research interest is in knowledge translation in primary care, across the spectrum of respiratory illness, with a focus on electronic tools, and asthma. He also has an interest in rare lung disease epidemiology and research methods, particularly liver-lung interactions and the Hepatopulmonary Syndrome. He serves as Vice-Chair of the Canadian Respiratory Guidelines Committee, as an investigator in the Pulmonary Vascular Complications of Liver Disease Research Consortium, and as the Global Television Evening News Medical Correspondent.

Recent Publications

  1. Gupta, S, Batt, J, Bourbeau, J, Chapman, KR, Gershon, A, Granton, J et al.. Triaging Access to Critical Care Resources in Patients With Chronic Respiratory Diseases in the Event of a Major COVID-19 Surge: Key Highlights From the Canadian Thoracic Society (CTS) Position Statement. Chest. 2020; :. doi: 10.1016/j.chest.2020.07.018. PubMed PMID:32693101 PubMed Central PMC7368654.
  2. Kouri, A, Gupta, S, Yadollahi, A, Ryan, CM, Gershon, AS, To, T et al.. Addressing Reduced Laboratory-Based Pulmonary Function Testing During a Pandemic. Chest. 2020; :. doi: 10.1016/j.chest.2020.06.065. PubMed PMID:32652095 PubMed Central PMC7345485.
  3. Rao, S, Pitel, B, Wagner, AH, Boca, SM, McCoy, M, King, I et al.. Collaborative, Multidisciplinary Evaluation of Cancer Variants Through Virtual Molecular Tumor Boards Informs Local Clinical Practices. JCO Clin Cancer Inform. 2020;4 :602-613. doi: 10.1200/CCI.19.00169. PubMed PMID:32644817 PubMed Central PMC7397775.
  4. Gupta, S, Bharti, B, Ahnen, DJ, Buchanan, DD, Cheng, IC, Cotterchio, M et al.. Potential impact of family history-based screening guidelines on the detection of early-onset colorectal cancer. Cancer. 2020;126 (13):3013-3020. doi: 10.1002/cncr.32851. PubMed PMID:32307706 .
  5. Preteroti, M, Whitmore, GA, Vandemheen, KL, FitzGerald, JM, Lemière, C, Boulet, LP et al.. Population-based case-finding to identify subjects with undiagnosed asthma or COPD. Eur. Respir. J. 2020;55 (6):. doi: 10.1183/13993003.00024-2020. PubMed PMID:32299864 .
  6. Selvanathan, J, Aaron, SD, Sykes, JR, Vandemheen, KL, FitzGerald, JM, Ainslie, M et al.. Performance Characteristics of Spirometry With Negative Bronchodilator Response and Methacholine Challenge Testing and Implications for Asthma Diagnosis. Chest. 2020;158 (2):479-490. doi: 10.1016/j.chest.2020.03.052. PubMed PMID:32298731 .
  7. Lam Shin Cheung, J, Paolucci, N, Price, C, Sykes, J, Gupta, S, Canadian Respiratory Research Network et al.. A system uptake analysis and GUIDES checklist evaluation of the Electronic Asthma Management System: A point-of-care computerized clinical decision support system. J Am Med Inform Assoc. 2020;27 (5):726-737. doi: 10.1093/jamia/ocaa019. PubMed PMID:32274495 PubMed Central PMC7309244.
  8. Poureslami, I, Shum, J, Kopec, J, Sawatzky, R, Gupta, S, Pakhale, S et al.. Development and Pretesting of a New Functional-Based Health Literacy Measurement Tool for Chronic Obstructive Pulmonary Disease (COPD) and Asthma Management. Int J Chron Obstruct Pulmon Dis. 2020;15 :613-625. doi: 10.2147/COPD.S234418. PubMed PMID:32256062 PubMed Central PMC7094165.
  9. Poureslami, I, Shum, J, Goldstein, R, Gupta, S, Aaron, SD, Lavoie, KL et al.. Asthma and COPD patients' perceived link between health literacy core domains and self-management of their condition. Patient Educ Couns. 2020;103 (7):1415-1421. doi: 10.1016/j.pec.2020.02.011. PubMed PMID:32087989 .
  10. Lam Shin Cheung, J, Naimi, M, Sykes, J, Gupta, S. A Role for Alveolar Exhaled Nitric Oxide Measurement in the Diagnosis of Hepatopulmonary Syndrome. J. Clin. Gastroenterol. 2020;54 (3):278-283. doi: 10.1097/MCG.0000000000001246. PubMed PMID:31306341 .
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Affiliations & Other Activities

  • Staff Respirologist, Division of Respirology, St. Michael’s Hospital
  • Michael Locke Chair in Knowledge Translation and Rare Lung Diseases, St. Michael’s Hospital
  • Assistant Professor, Department of Medicine, Division of Respirology, University of Toronto
  • Vice-Chair, Canadian Respiratory Guidelines Committee