Sandro B. Rizoli


Scientist, Keenan Research Centre for Biomedical Science


Dr. Sandro Rizoli received his Doctor of Medicine and completed a General Surgery residency in Brazil. Following medical school and residency, he moved to Canada in 1992 where he underwent a second residency in General Surgery, fellowships in Trauma and Critical Care and a Doctor of Philosophy under Dr. Ori Rotstein, St. Michael’s Surgeon-in-Chief.

In July 2002, Dr. Rizoli became Assistant Professor of Surgery and Critical Care Medicine at Sunnybrook, and was promoted to Full Professor in 2012. His life-long research focuses fall into two major areas: The immunological and anti-inflammatory effects of hypertonic fluids; and the physiopathology and management of hemorrhagic shock in trauma.

Dr. Rizoli was also appointed as the first St. Michael’s Hospital-University of Toronto Endowed Chair in Trauma Research beginning in July 2013. The five-year chair will support Dr. Rizoli’s research and innovation in trauma care. As a national leader in trauma resuscitation research, he plans to use the chair’s support to continue his work in developing new, more effective approaches to stopping life-threatening bleeding and ensuring that blood products are used appropriately in acute trauma patients.

As the director of trauma at St. Michael’s Hospital, Dr. Rizoli is uniquely positioned to apply his research discoveries to improve outcomes for trauma patients. St. Michael’s is one of 11 Ontario hospitals designated by the Ontario Ministry of Health and Long-Term Care as a Level 1 trauma center, equipped to receive the most severely injured patients.

Dr. Rizoli is also a full professor in the Department of Surgery and Critical Care Medicine at the University of Toronto and a research scientist at the Keenan Research Centre of the Li Ka Shing Knowledge Institute, chief of Region XII (Eastern Canada) of the Committee on Trauma of the American College of Surgeons and president of the Trauma Association of Canada.

Recent Publications

  1. Coccolini, F, Roberts, D, Ansaloni, L, Ivatury, R, Gamberini, E, Kluger, Y et al.. The open abdomen in trauma and non-trauma patients: WSES guidelines. World J Emerg Surg. 2018;13 :7. doi: 10.1186/s13017-018-0167-4. PubMed PMID:29434652 PubMed Central PMC5797335.
  2. de'Angelis, N, Di Saverio, S, Chiara, O, Sartelli, M, Martínez-Pérez, A, Patrizi, F et al.. 2017 WSES guidelines for the management of iatrogenic colonoscopy perforation. World J Emerg Surg. 2018;13 :5. doi: 10.1186/s13017-018-0162-9. PubMed PMID:29416554 PubMed Central PMC5784542.
  3. Sanders, S, Tien, H, Callum, J, Nascimento, B, Peng, H, Funk, C et al.. Fibrinogen Concentrate in the Special Operations Forces Environment. Mil Med. 2018;183 (1-2):e45-e50. doi: 10.1093/milmed/usx057. PubMed PMID:29401352 .
  4. Buick, JE, Drennan, IR, Scales, DC, Brooks, SC, Byers, A, Cheskes, S et al.. Improving Temporal Trends in Survival and Neurological Outcomes After Out-of-Hospital Cardiac Arrest. Circ Cardiovasc Qual Outcomes. 2018;11 (1):e003561. doi: 10.1161/CIRCOUTCOMES.117.003561. PubMed PMID:29317455 PubMed Central PMC5791528.
  5. Ley, EJ, Leonard, SD, Barmparas, G, Dhillon, NK, Inaba, K, Salim, A et al.. Beta blockers in critically ill patients with traumatic brain injury: Results from a multicenter, prospective, observational American Association for the Surgery of Trauma study. J Trauma Acute Care Surg. 2018;84 (2):234-244. doi: 10.1097/TA.0000000000001747. PubMed PMID:29251711 .
  6. Hylands, M, Toma, A, Beaudoin, N, Frenette, AJ, D'Aragon, F, Belley-Côté, É et al.. Early vasopressor use following traumatic injury: a systematic review. BMJ Open. 2017;7 (11):e017559. doi: 10.1136/bmjopen-2017-017559. PubMed PMID:29151048 PubMed Central PMC5701980.
  7. Landry, CH, Allan, KS, Connelly, KA, Cunningham, K, Morrison, LJ, Dorian, P et al.. Sudden Cardiac Arrest during Participation in Competitive Sports. N. Engl. J. Med. 2017;377 (20):1943-1953. doi: 10.1056/NEJMoa1615710. PubMed PMID:29141175 PubMed Central PMC5726886.
  8. da Costa, LGV, Carmona, MJC, Malbouisson, LM, Rizoli, S, Rocha-Filho, JA, Cardoso, RG et al.. Independent early predictors of mortality in polytrauma patients: a prospective, observational, longitudinal study. Clinics (Sao Paulo). 2017;72 (8):461-468. doi: 10.6061/clinics/2017(08)02. PubMed PMID:28954004 PubMed Central PMC5577616.
  9. Taylor, JR 3rd, Fox, EE, Holcomb, JB, Rizoli, S, Inaba, K, Schreiber, MA et al.. The hyperfibrinolytic phenotype is the most lethal and resource intense presentation of fibrinolysis in massive transfusion patients. J Trauma Acute Care Surg. 2018;84 (1):25-30. doi: 10.1097/TA.0000000000001699. PubMed PMID:28914713 PubMed Central PMC5739990.
  10. Simões, RL, Dorigatti, AE, Silveira, HJV, Calderan, TRA, Rizoli, S, Fraga, GP et al.. Trauma Leagues-A Novel Option to Attract Medical Students to a Surgical Career. World J Surg. 2018;42 (2):549-556. doi: 10.1007/s00268-017-4190-5. PubMed PMID:28913597 .
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Affiliations & Other Activities

  • Medical Director, Trauma and Acute Care Surgery, St. Michael’s Hospital
  • Chair in Trauma Research, St. Michael’s Hospital
  • Professor, Surgery and Critical Care Medicine, University of Toronto