Sean B. Rourke


Scientist, Li Ka Shing Knowledge Institute


Sean B. Rourke is a Clinical Neuropsychologist and Scientist at St. Michael’s Hospital, Professor of Psychiatry, University of Toronto, and Scientific and Executive Director of the Ontario Ministry of Health Acquired Immune Deficiency Syndrome (AIDS) Bureau-funded Ontario Human Immunodeficiency Virus (HIV) Treatment Network, a leading research and policy organization in Canada. He is also the Director of three national centres funded by Canadian Institutes of Health Researcg (CIHR), the CIHR Centre for Reach on HIV/AIDS (for population health and health services), Community-Based Research (CBR) Collaboration Centre for HIV, and Universities Without Walls (a CIHR Strategic Training Initiative in Health Research (STIHR) that is training the next generation of HIV researchers in Canada).

Sean is transforming how population health and community-based research is done to have a stronger impact on policies and front-line services, and to solve complex health problems for people living with or at risk for HIV/AIDS. With his novel effective approach to community stakeholder engagement, partnership development across disciplines and sectors, and innovative knowledge transfer and exchange and research-to-action strategies, Sean is having a major influence in getting us closer to ending the HIV epidemic in Canada.

Recent Publications

  1. Benoit, AC, Younger, J, Beaver, K, Jackson, R, Loutfy, M, Masching, R et al.. Increased mortality among Indigenous persons in a multisite cohort of people living with HIV in Canada. Can J Public Health. 2017;108 (2):e169-e175. . PubMed PMID:28621653 .
  2. Vardy, JL, Stouten-Kemperman, MM, Pond, G, Booth, CM, Rourke, SB, Dhillon, HM et al.. A mechanistic cohort study evaluating cognitive impairment in women treated for breast cancer. Brain Imaging Behav. 2017; :. doi: 10.1007/s11682-017-9728-5. PubMed PMID:28466438 .
  3. Patterson, S, Jose, S, Samji, H, Cescon, A, Ding, E, Zhu, J et al.. A tale of two countries: all-cause mortality among people living with HIV and receiving combination antiretroviral therapy in the UK and Canada. HIV Med. 2017; :. doi: 10.1111/hiv.12505. PubMed PMID:28440036 .
  4. Antoniou, T, Szadkowski, L, Walmsley, S, Cooper, C, Burchell, AN, Bayoumi, AM et al.. Comparison of atazanavir/ritonavir and darunavir/ritonavir based antiretroviral therapy for antiretroviral naïve patients. BMC Infect. Dis. 2017;17 (1):266. doi: 10.1186/s12879-017-2379-8. PubMed PMID:28399819 PubMed Central PMC5387339.
  5. Rossi, C, Raboud, J, Walmsley, S, Cooper, C, Antoniou, T, Burchell, AN et al.. Hepatitis C co-infection is associated with an increased risk of incident chronic kidney disease in HIV-infected patients initiating combination antiretroviral therapy. BMC Infect. Dis. 2017;17 (1):246. doi: 10.1186/s12879-017-2350-8. PubMed PMID:28376824 PubMed Central PMC5381089.
  6. OʼNeill, TJ, Raboud, JM, Tinmouth, J, Rourke, SB, Rueda, S, Hart, TA et al.. Gastrointestinal Symptom Distress is Associated With Worse Mental and Physical Health-Related Quality of Life. J. Acquir. Immune Defic. Syndr. 2017;75 (1):67-76. doi: 10.1097/QAI.0000000000001309. PubMed PMID:28177965 .
  7. Bekele, T, Rueda, S, Gardner, S, Raboud, J, Smieja, M, Kennedy, R et al.. Trends and Correlates of Cigarette Smoking and Its Impacts on Health-Related Quality of Life Among People Living with HIV: Findings from the Ontario HIV Treatment Network Cohort Study, 2008-2014. AIDS Patient Care STDS. 2017;31 (2):49-59. doi: 10.1089/apc.2016.0174. PubMed PMID:28170303 .
  8. Rachlis, B, Burchell, AN, Gardner, S, Light, L, Raboud, J, Antoniou, T et al.. Social determinants of health and retention in HIV care in a clinical cohort in Ontario, Canada. AIDS Care. 2017;29 (7):828-837. doi: 10.1080/09540121.2016.1271389. PubMed PMID:28027668 .
  9. Kendall, CE, Chalifoux, M, Manuel, D, Reinhard, R, Robinson, G, Bacon, J et al.. A Population-Based Study of Care at the End of Life Among People With HIV in Ontario From 2010 to 2013. J. Acquir. Immune Defic. Syndr. 2017;75 (1):e1-e7. doi: 10.1097/QAI.0000000000001268. PubMed PMID:27984556 PubMed Central PMC5389586.
  10. Gillis, J, Loutfy, M, Bayoumi, AM, Antoniou, T, Burchell, AN, Walmsley, S et al.. A Multi-State Model Examining Patterns of Transitioning Among States of Engagement in Care in HIV-Positive Individuals Initiating Combination Antiretroviral Therapy. J. Acquir. Immune Defic. Syndr. 2016;73 (5):531-539. doi: 10.1097/QAI.0000000000001109. PubMed PMID:27851713 PubMed Central PMC5119642.
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Affiliations & Other Activities

  • Professor of Psychiatry, University of Toronto
  • Scientific and Executive Director, Ontario HIV Treatment Network
  • Director, CIHR Centre for REACH in HIV/AIDS
  • Director, CIHR CBR Collaborative Centre
  • Director, Universities Without Walls