Sidney Kennedy


Scientist, Li Ka Shing Knowledge Institute

Research Programs


Dr. Sidney H. Kennedy is Professor of Psychiatry at the University of Toronto, the Arthur Sommer Rotenberg Chair in Suicide and Depression Studies, and a Scientist at Li Ka Shing Knowledge Institute and Toronto Western Research Institute, Toronto, Canada. Dr. Kennedy is the lead investigator for a large depression biomarker initiative. He has published extensively on new drug evaluation, neuroimaging and neurostimulation therapies, personality factors in depression, antidepressant effects on sexual function and treatment guidelines for Major Depressive Disorder and Bipolar Disorder.

Dr. Kennedy is the Immediate Past President of the International Society for Affective Disorders, former President of the Canadian College of Neuropsychopharmacology, and the founding chair of the Canadian Network for Mood and Anxiety Treatments (CANMAT).

He has published more than 350 peer reviewed publications and 11 books on depression and related topics.

Recent Publications

  1. Papageorghiou, AT, Kennedy, SH, Salomon, LJ, Altman, DG, Ohuma, EO, Stones, W et al.. The INTERGROWTH-21fetal growth standards: toward the global integration of pregnancy and pediatric care. Am. J. Obstet. Gynecol. 2018;218 (2S):S630-S640. doi: 10.1016/j.ajog.2018.01.011. PubMed PMID:29422205 .
  2. Maciukiewicz, M, Marshe, VS, Hauschild, AC, Foster, JA, Rotzinger, S, Kennedy, JL et al.. GWAS-based machine learning approach to predict duloxetine response in major depressive disorder. J Psychiatr Res. 2018;99 :62-68. doi: 10.1016/j.jpsychires.2017.12.009. PubMed PMID:29407288 .
  3. Ghanean, H, Ceniti, AK, Kennedy, SH. Fatigue in Patients with Major Depressive Disorder: Prevalence, Burden and Pharmacological Approaches to Management. CNS Drugs. 2018; :. doi: 10.1007/s40263-018-0490-z. PubMed PMID:29383573 .
  4. Lee, Y, Carmona, NE, Shekotikhina, M, Subramaniapillai, M, Mansur, RB, Cha, DS et al.. Is binge eating a cognitive disorder? Results from the International Mood Disorders Collaborative Project. Ann Clin Psychiatry. 2018;30 (1):25-31. . PubMed PMID:29373615 .
  5. Kennedy, SH, Grouin, JM, Cadour, S, Robert, V, Picarel-Blanchot, F. Relative short-term efficacy and acceptability of agomelatine versus vortioxetine in adult patients suffering from major depressive disorder. Hum Psychopharmacol. 2018;33 (1):. doi: 10.1002/hup.2646. PubMed PMID:29327372 .
  6. Kennedy, SH, Ceniti, AK. Unpacking Major Depressive Disorder: From Classification to Treatment Selection. Can J Psychiatry. 2017; :706743717748883. doi: 10.1177/0706743717748883. PubMed PMID:29278937 .
  7. Villar, J, Cheikh Ismail, L, Staines Urias, E, Giuliani, F, Ohuma, EO, Victora, CG et al.. The satisfactory growth and development at 2 years of age of the INTERGROWTH-21Fetal Growth Standards cohort support its appropriateness for constructing international standards. Am. J. Obstet. Gynecol. 2018;218 (2S):S841-S854.e2. doi: 10.1016/j.ajog.2017.11.564. PubMed PMID:29273309 PubMed Central PMC5807090.
  8. Kennedy, SH, Wittchen, HU. Editorial: mood and anxiety disorders. Curr Opin Psychiatry. 2018;31 (1):1-2. doi: 10.1097/YCO.0000000000000386. PubMed PMID:29176393 .
  9. Baskaran, A, Farzan, F, Milev, R, Brenner, CA, Alturi, S, Pat McAndrews, M et al.. The comparative effectiveness of electroencephalographic indices in predicting response to escitalopram therapy in depression: A pilot study. J Affect Disord. 2018;227 :542-549. doi: 10.1016/j.jad.2017.10.028. PubMed PMID:29169123 .
  10. Fonseka, TM, MacQueen, GM, Kennedy, SH. Neuroimaging biomarkers as predictors of treatment outcome in Major Depressive Disorder. J Affect Disord. 2017; :. doi: 10.1016/j.jad.2017.10.049. PubMed PMID:29150145 .
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Affiliations & Other Activities

  • Staff Physician, Department of Mental Health, St. Michael’s Hospital
  • Professor, Department of Psychiatry, University of Toronto
  • Research Scientist, Krembil Neurosciences, University Health Network