Subodh Verma

MD, FRCSC, FAHA, PhD

Scientist, Keenan Research Centre for Biomedical Science

Biography

Dr. Subodh Verma is a cardiac surgeon-scientist at St. Michael’s Hospital, Professor at the University of Toronto and the Canada Research Chair in Atherosclerosis. He has been on the India Abroad Power List, recognized as one of Canada’s Top 40 under 40, and honoured with the Howard Morgan Award from the International Academy of Cardiovascular Sciences and the Royal College of Physicians and Surgeons of Canada Gold Medal in Surgery. He is a member of the Royal Society of Canada College of New Scholars, Artists and Scientists, and an inductee of the American Association of Thoracic Surgeons. Dr. Verma runs a practice that encompasses the entire spectrum of adult cardiac surgery (with a special interest in mitral valve repair and bicuspid aortopathy).

He is involved in several clinical trials and oversees a dynamic pre-clinical research laboratory that focuses on the roles of risk factors, inflammation and autophagy in cardiovascular health. His innovative research has culminated in nearly 300 peer-reviewed papers and two United States patents. Dr. Verma’s meta-analysis revealing that bypass surgery is superior to angioplasty in patients with diabetes has been used by the American College of Cardiology and the Canadian Cardiovascular Society (CCS) to shape the recommendations around the best clinical choice for revascularization procedures involving individuals with diabetes. He has contributed to the CCS guidelines for antiplatelet therapy, atrial fibrillation, dyslipidemia, peripheral arterial disease, and stable coronary artery disease; Canadian Cardiovascular Surgery Position Statement and Canadian Cardiometabolic Risk Position Paper. Dr. Verma spearheads the CARDIOLINK platform that will conduct clinical trials in atrial fibrillation, aneurysm and cerebral protection, diabetes and secondary prevention, valvular heart disease, and critical limb ischemia. He (co-)founded and (co-)chairs many regional and national educational initiatives that include the Landmark Lecture, State of the Heart Symposium, Toronto Acute Coronary Syndrome Summit, St. Michael’s Heart Valve Summit, Advances in Cardiology, Current Issues in Cardiology, and At the Heart of Diabetes programs.

 

Recent Publications

  1. Mazine, A, Rocha, RV, El-Hamamsy, I, Ouzounian, M, Yanagawa, B, Bhatt, DL et al.. Ross Procedure vs Mechanical Aortic Valve Replacement in Adults: A Systematic Review and Meta-analysis. JAMA Cardiol. 2018;3 (10):978-987. doi: 10.1001/jamacardio.2018.2946. PubMed PMID:30326489 .
  2. Salata, K, Hussain, MA, De Mestral, C, Greco, E, Mamdani, M, Tu, JV et al.. Validation of abdominal aortic aneurysm repair codes in Ontario administrative data. Clin Invest Med. 2018;41 (3):E148-E155. . PubMed PMID:30315751 .
  3. Mancini, GBJ, Cheng, AY, Connelly, K, Fitchett, D, Goldenberg, R, Goodman, S et al.. CardioDiabetes: Core Competencies for Cardiovascular Clinicians in a Rapidly Evolving Era of Type 2 Diabetes Management. Can J Cardiol. 2018;34 (10):1350-1361. doi: 10.1016/j.cjca.2018.07.010. PubMed PMID:30269832 .
  4. Kumar, N, Garg, A, Bhatt, DL, Sabongui, S, Gupta, N, Chaudhry, S et al.. Empagliflozin improves cardiorespiratory fitness in type 2 diabetes: Translational implications. Can. J. Physiol. Pharmacol. 2018; :. doi: 10.1139/cjpp-2018-0359. PubMed PMID:30265814 .
  5. Christopher, B, Nadine R., C, Mohamad A., H, Ahmed, K, Subodh, V, Mohammed, AO et al.. Peripheral artery disease among Indigenous Canadians: What do we know?. Can J Surg. 2018;61 (5):305-310. doi: 10.1503/cjs.011718. PubMed PMID:30246980 PubMed Central PMC6153097.
  6. Altamimi, TR, Chowdhury, B, Singh, KK, Zhang, L, Mahmood, MU, Pan, Y et al.. A novel role of endothelial autophagy as a regulator of myocardial fatty acid oxidation. J. Thorac. Cardiovasc. Surg. 2018; :. doi: 10.1016/j.jtcvs.2018.07.047. PubMed PMID:30195591 .
  7. Dos Santos, CC, Gopal, B, Verma, S. Metformin: An Old Dog with a New Trick?. Cell Metab. 2018;28 (3):334-336. doi: 10.1016/j.cmet.2018.08.018. PubMed PMID:30184483 .
  8. Tam, DY, Yanagawa, B, Verma, S, Ruel, M, Fremes, SE, Mazine, A et al.. Early vs Late Surgery for Patients With Endocarditis and Neurological Injury: A Systematic Review and Meta-analysis. Can J Cardiol. 2018;34 (9):1185-1199. doi: 10.1016/j.cjca.2018.05.010. PubMed PMID:30170674 .
  9. Opingari, E, Partridge, ACR, Verma, S, Bajaj, HS. SGLT2 inhibitors: practical considerations and recommendations for cardiologists. Curr. Opin. Cardiol. 2018;33 (6):676-682. doi: 10.1097/HCO.0000000000000561. PubMed PMID:30148719 .
  10. Mazer, CD, Whitlock, RP, Fergusson, DA, Belley-Cote, E, Connolly, K, Khanykin, B et al.. Six-Month Outcomes after Restrictive or Liberal Transfusion for Cardiac Surgery. N. Engl. J. Med. 2018;379 (13):1224-1233. doi: 10.1056/NEJMoa1808561. PubMed PMID:30146969 .
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Affiliations & Other Activities

  • Staff Surgeon, Division of Cardiology , St. Michael’s Hospital
  • Professor, Department of Surgery and Pharmacology & Toxicology, University of Toronto
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