Subodh Verma

MD, FRCSC, FAHA, PhD

Scientist, Keenan Research Centre for Biomedical Science

Biography

Dr. Subodh Verma is a cardiac surgeon-scientist at St. Michael’s Hospital, Professor at the University of Toronto and the Canada Research Chair in Atherosclerosis. He has been on the India Abroad Power List, recognized as one of Canada’s Top 40 under 40, and honoured with the Howard Morgan Award from the International Academy of Cardiovascular Sciences and the Royal College of Physicians and Surgeons of Canada Gold Medal in Surgery. He is a member of the Royal Society of Canada College of New Scholars, Artists and Scientists, and an inductee of the American Association of Thoracic Surgeons. Dr. Verma runs a practice that encompasses the entire spectrum of adult cardiac surgery (with a special interest in mitral valve repair and bicuspid aortopathy).

He is involved in several clinical trials and oversees a dynamic pre-clinical research laboratory that focuses on the roles of risk factors, inflammation and autophagy in cardiovascular health. His innovative research has culminated in nearly 300 peer-reviewed papers and two United States patents. Dr. Verma’s meta-analysis revealing that bypass surgery is superior to angioplasty in patients with diabetes has been used by the American College of Cardiology and the Canadian Cardiovascular Society (CCS) to shape the recommendations around the best clinical choice for revascularization procedures involving individuals with diabetes. He has contributed to the CCS guidelines for antiplatelet therapy, atrial fibrillation, dyslipidemia, peripheral arterial disease, and stable coronary artery disease; Canadian Cardiovascular Surgery Position Statement and Canadian Cardiometabolic Risk Position Paper. Dr. Verma spearheads the CARDIOLINK platform that will conduct clinical trials in atrial fibrillation, aneurysm and cerebral protection, diabetes and secondary prevention, valvular heart disease, and critical limb ischemia. He (co-)founded and (co-)chairs many regional and national educational initiatives that include the Landmark Lecture, State of the Heart Symposium, Toronto Acute Coronary Syndrome Summit, St. Michael’s Heart Valve Summit, Advances in Cardiology, Current Issues in Cardiology, and At the Heart of Diabetes programs.

 

Recent Publications

  1. Yanagawa, B, Rocha, RV, Mazine, A, Verma, S, Mazer, CD, Vernich, L et al.. Hemoglobin Optimization for Coronary Bypass: A Ten-Year Canadian Multicenter Experience. Ann. Thorac. Surg. 2018; :. doi: 10.1016/j.athoracsur.2018.10.067. PubMed PMID:30529670 .
  2. Connelly, KA, Bhatt, DL, Verma, S. Can We DECLARE a Victory against Cardio-Renal Disease in Diabetes?. Cell Metab. 2018;28 (6):813-815. doi: 10.1016/j.cmet.2018.11.010. PubMed PMID:30517896 .
  3. Mazine, A, El-Hamamsy, I, Verma, S, Peterson, MD, Bonow, RO, Yacoub, MH et al.. Ross Procedure in Adults for Cardiologists and Cardiac Surgeons: JACC State-of-the-Art Review. J. Am. Coll. Cardiol. 2018;72 (22):2761-2777. doi: 10.1016/j.jacc.2018.08.2200. PubMed PMID:30497563 .
  4. Verma, S, Rawat, S, Ho, KL, Wagg, CS, Zhang, L, Teoh, H et al.. Empagliflozin Increases Cardiac Energy Production in Diabetes: Novel Translational Insights Into the Heart Failure Benefits of SGLT2 Inhibitors. JACC Basic Transl Sci. 2018;3 (5):575-587. doi: 10.1016/j.jacbts.2018.07.006. PubMed PMID:30456329 PubMed Central PMC6234616.
  5. Verma, S, Jüni, P, Mazer, CD. Pump, pipes, and filter: do SGLT2 inhibitors cover it all?. Lancet. 2018; :. doi: 10.1016/S0140-6736(18)32824-1. PubMed PMID:30424891 .
  6. Ridker, PM, Everett, BM, Pradhan, A, MacFadyen, JG, Solomon, DH, Zaharris, E et al.. Low-Dose Methotrexate for the Prevention of Atherosclerotic Events. N. Engl. J. Med. 2018; :. doi: 10.1056/NEJMoa1809798. PubMed PMID:30415610 .
  7. Andrade, JG, Verma, A, Mitchell, LB, Parkash, R, Leblanc, K, Atzema, C et al.. 2018 Focused Update of the Canadian Cardiovascular Society Guidelines for the Management of Atrial Fibrillation. Can J Cardiol. 2018;34 (11):1371-1392. doi: 10.1016/j.cjca.2018.08.026. PubMed PMID:30404743 .
  8. Verma, S, Mazer, CD, Bhatt, DL. The perils of polyvascular disease in type 2 diabetes. Lancet Diabetes Endocrinol. 2018;6 (12):914-916. doi: 10.1016/S2213-8587(18)30311-5. PubMed PMID:30396866 .
  9. Salata, K, Syed, M, Hussain, MA, de Mestral, C, Greco, E, Mamdani, M et al.. Statins Reduce Abdominal Aortic Aneurysm Growth, Rupture, and Perioperative Mortality: A Systematic Review and Meta-Analysis. J Am Heart Assoc. 2018;7 (19):e008657. doi: 10.1161/JAHA.118.008657. PubMed PMID:30371297 .
  10. Hussain, MA, Saposnik, G, Raju, S, Salata, K, Mamdani, M, Tu, JV et al.. Association Between Statin Use and Cardiovascular Events After Carotid Artery Revascularization. J Am Heart Assoc. 2018;7 (16):e009745. doi: 10.1161/JAHA.118.009745. PubMed PMID:30369318 PubMed Central PMC6201401.
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Affiliations & Other Activities

  • Staff Surgeon, Division of Cardiology , St. Michael’s Hospital
  • Professor, Department of Surgery and Pharmacology & Toxicology, University of Toronto
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