Subodh Verma

MD, FRCSC, FAHA, PhD

Scientist, Keenan Research Centre for Biomedical Science

Biography

Dr. Subodh Verma is a cardiac surgeon-scientist at St. Michael’s Hospital, Professor at the University of Toronto and the Canada Research Chair in Atherosclerosis. He has been on the India Abroad Power List, recognized as one of Canada’s Top 40 under 40, and honoured with the Howard Morgan Award from the International Academy of Cardiovascular Sciences and the Royal College of Physicians and Surgeons of Canada Gold Medal in Surgery. He is a member of the Royal Society of Canada College of New Scholars, Artists and Scientists, and an inductee of the American Association of Thoracic Surgeons. Dr. Verma runs a practice that encompasses the entire spectrum of adult cardiac surgery (with a special interest in mitral valve repair and bicuspid aortopathy).

He is involved in several clinical trials and oversees a dynamic pre-clinical research laboratory that focuses on the roles of risk factors, inflammation and autophagy in cardiovascular health. His innovative research has culminated in nearly 300 peer-reviewed papers and two United States patents. Dr. Verma’s meta-analysis revealing that bypass surgery is superior to angioplasty in patients with diabetes has been used by the American College of Cardiology and the Canadian Cardiovascular Society (CCS) to shape the recommendations around the best clinical choice for revascularization procedures involving individuals with diabetes. He has contributed to the CCS guidelines for antiplatelet therapy, atrial fibrillation, dyslipidemia, peripheral arterial disease, and stable coronary artery disease; Canadian Cardiovascular Surgery Position Statement and Canadian Cardiometabolic Risk Position Paper. Dr. Verma spearheads the CARDIOLINK platform that will conduct clinical trials in atrial fibrillation, aneurysm and cerebral protection, diabetes and secondary prevention, valvular heart disease, and critical limb ischemia. He (co-)founded and (co-)chairs many regional and national educational initiatives that include the Landmark Lecture, State of the Heart Symposium, Toronto Acute Coronary Syndrome Summit, St. Michael’s Heart Valve Summit, Advances in Cardiology, Current Issues in Cardiology, and At the Heart of Diabetes programs.

 

Recent Publications

  1. Syed, MH, Hussain, MA, Khoshhal, Z, Salata, K, Altuwaijri, B, Hughes, B et al.. Thirty-day hospital readmission and emergency department visits after vascular surgery: a Canadian prospective cohort study. Can J Surg. 2018;61 (4):257-263. . PubMed PMID:30067184 PubMed Central PMC6066379.
  2. Byrne, NJ, Parajuli, N, Levasseur, JL, Boisvenue, J, Beker, DL, Masson, G et al.. Empagliflozin Prevents Worsening of Cardiac Function in an Experimental Model of Pressure Overload-Induced Heart Failure. JACC Basic Transl Sci. 2017;2 (4):347-354. doi: 10.1016/j.jacbts.2017.07.003. PubMed PMID:30062155 PubMed Central PMC6034464.
  3. Borger, MA, Fedak, PWM, Stephens, EH, Gleason, TG, Girdauskas, E, Ikonomidis, JS et al.. The American Association for Thoracic Surgery consensus guidelines on bicuspid aortic valve-related aortopathy: Full online-only version. J. Thorac. Cardiovasc. Surg. 2018;156 (2):e41-e74. doi: 10.1016/j.jtcvs.2018.02.115. PubMed PMID:30011777 .
  4. Borger, MA, Fedak, PWM, Stephens, EH, Gleason, TG, Girdauskas, E, Ikonomidis, JS et al.. The American Association for Thoracic Surgery consensus guidelines on bicuspid aortic valve-related aortopathy: Executive summary. J. Thorac. Cardiovasc. Surg. 2018;156 (2):473-480. doi: 10.1016/j.jtcvs.2017.10.161. PubMed PMID:30011756 .
  5. Harrington, JL, de Albuquerque Rocha, N, Patel, KV, Verma, S, McGuire, DK. Should Metformin Remain First-Line Medical Therapy for Patients with Type 2 Diabetes Mellitus and Atherosclerotic Cardiovascular Disease? An Alternative Approach. Curr. Diab. Rep. 2018;18 (9):64. doi: 10.1007/s11892-018-1035-z. PubMed PMID:30008022 .
  6. Yanagawa, B, Verma, S, Bagai, A, Puskas, JD. Should functional assessment of lesion severity be used to guide coronary bypass?. Curr. Opin. Cardiol. 2018;33 (5):565-570. doi: 10.1097/HCO.0000000000000549. PubMed PMID:29994809 .
  7. Yanagawa, B, Hong, K, Cheema, A, Bagai, A, Verma, S. What is the state of hybrid coronary revascularization in 2018?. Curr. Opin. Cardiol. 2018;33 (5):540-545. doi: 10.1097/HCO.0000000000000548. PubMed PMID:29994806 .
  8. Tobias, DK, Mora, S, Verma, S, Lawler, PR. Altered branched chain amino acid metabolism: toward a unifying cardiometabolic hypothesis. Curr. Opin. Cardiol. 2018;33 (5):558-564. doi: 10.1097/HCO.0000000000000552. PubMed PMID:29994805 .
  9. Luu, VZ, Chowdhury, B, Al-Omran, M, Hess, DA, Verma, S. Role of endothelial primary cilia as fluid mechanosensors on vascular health. Atherosclerosis. 2018;275 :196-204. doi: 10.1016/j.atherosclerosis.2018.06.818. PubMed PMID:29945035 .
  10. Cherney, DZI, Verma, S, Parker, JD. Dulaglutide and renal protection in type 2 diabetes. Lancet Diabetes Endocrinol. 2018;6 (8):588-590. doi: 10.1016/S2213-8587(18)30125-6. PubMed PMID:29910025 .
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Affiliations & Other Activities

  • Staff Surgeon, Division of Cardiology , St. Michael’s Hospital
  • Professor, Department of Surgery and Pharmacology & Toxicology, University of Toronto
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