Sunit Das

MD, PhD, MA, BA

Scientist, Keenan Research Centre for Biomedical Science

Biography

Dr. Sunit Das is a Scientist in the Keenan Research Centre for Biomedical Science and neurosurgeon at St.Michael’s Hospital. He is an Assistant Professor in the Department of Surgery at the University of Toronto. Dr. Das studied English Literature at the University of Michigan and Philosophy at Harvard University before moving to Chicago for medical school at Northwestern University. He completed a Doctor of Philosophy at the National Institutes of Health, where he studied the molecular processes that underly adult neurogenesis in the lab of Dr. ZuHang Sheng. He returned to Chicago for his neurosurgical residency, during which time he also began work on cancer stem cells in primary brain tumours in the lab of Dr. John Kessler. He was recruited to the University of Toronto in 2010. Dr. Das’s clinical practice and clinical research focus of the treatment of patients with tumours of the brain and spine. His laboratory at the Hospital for SickKids focuses on non-coding RNA and control of cell identity in glioblastoma and neural stem cells. He is a member of the Arthur and Sonia Labatt Brain Tumour Research Centre at the Hospital for Sick Children, and faculty with the Institute of Medical Science and Department of Laboratory Medicine and Pathobiology.

Recent Publications

  1. Mansur, A, Hird, MA, Desimone, A, Pshonyak, I, Schweizer, TA, Das, S et al.. Driving habits and behaviors of patients with brain tumors: a self-report, cognitive and driving simulation study. Sci Rep. 2018;8 (1):4635. doi: 10.1038/s41598-018-22937-y. PubMed PMID:29545606 PubMed Central PMC5854700.
  2. Coluccia, D, Figueiredo, CA, Wu, MY, Riemenschneider, AN, Diaz, R, Luck, A et al.. Enhancing glioblastoma treatment using cisplatin-gold-nanoparticle conjugates and targeted delivery with magnetic resonance-guided focused ultrasound. Nanomedicine. 2018;14 (4):1137-1148. doi: 10.1016/j.nano.2018.01.021. PubMed PMID:29471172 .
  3. Man, HSJ, Sukumar, AN, Lam, GC, Turgeon, PJ, Yan, MS, Ku, KH et al.. Angiogenic patterning by STEEL, an endothelial-enriched long noncoding RNA. Proc. Natl. Acad. Sci. U.S.A. 2018;115 (10):2401-2406. doi: 10.1073/pnas.1715182115. PubMed PMID:29467285 PubMed Central PMC5877935.
  4. He, J, Mansouri, A, Das, S. Alpha Thalassemia/Mental Retardation Syndrome X-Linked, the Alternative Lengthening of Telomere Phenotype, and Gliomagenesis: Current Understandings and Future Potential. Front Oncol. 2017;7 :322. doi: 10.3389/fonc.2017.00322. PubMed PMID:29359122 PubMed Central PMC5766634.
  5. Mansur, A, Desimone, A, Vaughan, S, Schweizer, TA, Das, S. To drive or not to drive, that is still the question: current challenges in driving recommendations for patients with brain tumours. J. Neurooncol. 2018;137 (2):379-385. doi: 10.1007/s11060-017-2727-y. PubMed PMID:29294231 .
  6. Abdulsalam, HA, Nissiri, F, Das, S. Letter: Spontaneous Third Ventriculostomy in a Patient Following Traumatic Brain Injury. Oper Neurosurg (Hagerstown). 2018;14 (2):E26-E27. doi: 10.1093/ons/opx268. PubMed PMID:29182767 .
  7. Lam Shin Cheung, V, Kim, A, Sahgal, A, Das, S. Meningioma recurrence rates following treatment: a systematic analysis. J. Neurooncol. 2018;136 (2):351-361. doi: 10.1007/s11060-017-2659-6. PubMed PMID:29143273 .
  8. Wu, M, Guan, J, Li, C, Gunter, S, Nusrat, L, Ng, S et al.. Aberrantly activated Cox-2 and Wnt signaling interact to maintain cancer stem cells in glioblastoma. Oncotarget. 2017;8 (47):82217-82230. doi: 10.18632/oncotarget.19283. PubMed PMID:29137258 PubMed Central PMC5669884.
  9. Ironside, S, Das, S, Sahgal, A, Moroney, C, Mainprize, T, Perry, JR et al.. Optimal Therapies for Newly Diagnosed Elderly Patients with Glioblastoma. Curr Treat Options Oncol. 2017;18 (11):66. doi: 10.1007/s11864-017-0508-7. PubMed PMID:29080109 .
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Affiliations & Other Activities

  • Assistant Professor, Division of Neurosurgery, Department of Surgery, St. Michael’s Hospital
  • Adjunct Scientist, Brain Tumour Research Centre, Hospital for Sick Children
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