Sunit Das

MD, PhD, MA, BA

Scientist, Keenan Research Centre for Biomedical Science

Biography

Dr. Sunit Das is a Scientist in the Keenan Research Centre for Biomedical Science and neurosurgeon at St.Michael’s Hospital. He is an Assistant Professor in the Department of Surgery at the University of Toronto. Dr. Das studied English Literature at the University of Michigan and Philosophy at Harvard University before moving to Chicago for medical school at Northwestern University. He completed a Doctor of Philosophy at the National Institutes of Health, where he studied the molecular processes that underly adult neurogenesis in the lab of Dr. ZuHang Sheng. He returned to Chicago for his neurosurgical residency, during which time he also began work on cancer stem cells in primary brain tumours in the lab of Dr. John Kessler. He was recruited to the University of Toronto in 2010. Dr. Das’s clinical practice and clinical research focus of the treatment of patients with tumours of the brain and spine. His laboratory at the Hospital for SickKids focuses on non-coding RNA and control of cell identity in glioblastoma and neural stem cells. He is a member of the Arthur and Sonia Labatt Brain Tumour Research Centre at the Hospital for Sick Children, and faculty with the Institute of Medical Science and Department of Laboratory Medicine and Pathobiology.

Recent Publications

  1. Maslink, C, Cheng, K, Smith, TR, Das, S. Advanced age is not a universal predictor of poorer outcome in patients undergoing neurosurgery. World Neurosurg. 2019; :. doi: 10.1016/j.wneu.2019.06.093. PubMed PMID:31229751 .
  2. Maknojia, S, Tam, F, Das, S, Schweizer, T, Graham, SJ. Visualization of Brain Shift Corrected Functional Magnetic Resonance Imaging Data for Intraoperative Brain Mapping. World Neurosurg X. 2019;2 :100021. doi: 10.1016/j.wnsx.2019.100021. PubMed PMID:31218295 PubMed Central PMC6580887.
  3. Soliman, H, Myrehaug, S, Tseng, CL, Ruschin, M, Hashmi, A, Mainprize, T et al.. Image-Guided, Linac-Based, Surgical Cavity-Hypofractionated Stereotactic Radiotherapy in 5 Daily Fractions for Brain Metastases. Neurosurgery. 2019; :. doi: 10.1093/neuros/nyz162. PubMed PMID:31173150 .
  4. Das, S, McKneally, M. The Surgeon-in-Chief Should Oversee Innovative Surgical Practice. Am J Bioeth. 2019;19 (6):34-36. doi: 10.1080/15265161.2019.1602183. PubMed PMID:31135307 .
  5. Das, S, Morrison, M, Tam, F, Graham, S. Spatial reorganisation of the somatosensory cortex in a patient with a low-grade glioma. BMJ Case Rep. 2019;12 (5):. doi: 10.1136/bcr-2018-228971. PubMed PMID:31061181 .
  6. Nguyen, TK, Perry, J, Sundaram, ANE, Detsky, J, Maralani, PJ, Calabrese, E et al.. Rescue bevacizumab following symptomatic pseudoprogression of a tectal glioma post-radiotherapy: a case report and review of the literature. J. Neurooncol. 2019; :. doi: 10.1007/s11060-019-03179-y. PubMed PMID:31054097 .
  7. Kotecha, R, Mehta, MP, Chang, EL, Brown, PD, Suh, JH, Lo, SS et al.. Updates in the management of intradural spinal cord tumors: a radiation oncology focus. Neuro-oncology. 2019;21 (6):707-718. doi: 10.1093/neuonc/noz014. PubMed PMID:30977511 PubMed Central PMC6556849.
  8. Woolman, M, Kuzan-Fischer, CM, Ferry, I, Kiyota, T, Luu, B, Wu, M et al.. Picosecond Infrared Laser Desorption Mass Spectrometry Identifies Medulloblastoma Subgroups on Intrasurgical Timescales. Cancer Res. 2019;79 (9):2426-2434. doi: 10.1158/0008-5472.CAN-18-3411. PubMed PMID:30890619 .
  9. Wang, S, Ahuja, CS, Das, S. Arachnoiditis Ossificans: a Rare Etiology of Oil-Based Spinal Myelography and Review of Literature. World Neurosurg. 2019; :. doi: 10.1016/j.wneu.2019.02.178. PubMed PMID:30862590 .
  10. Lee, DD, Leão, R, Komosa, M, Gallo, M, Zhang, CH, Lipman, T et al.. DNA hypermethylation within TERT promoter upregulates TERT expression in cancer. J. Clin. Invest. 2019;129 (1):223-229. doi: 10.1172/JCI121303. PubMed PMID:30358567 PubMed Central PMC6307937.
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Affiliations & Other Activities

  • Assistant Professor, Division of Neurosurgery, Department of Surgery, St. Michael’s Hospital
  • Adjunct Scientist, Brain Tumour Research Centre, Hospital for Sick Children
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