Sunit Das


Scientist, Keenan Research Centre for Biomedical Science


Dr. Sunit Das is a Scientist in the Keenan Research Centre for Biomedical Science and neurosurgeon at St.Michael’s Hospital. He is an Assistant Professor in the Department of Surgery at the University of Toronto. Dr. Das studied English Literature at the University of Michigan and Philosophy at Harvard University before moving to Chicago for medical school at Northwestern University. He completed a Doctor of Philosophy at the National Institutes of Health, where he studied the molecular processes that underly adult neurogenesis in the lab of Dr. ZuHang Sheng. He returned to Chicago for his neurosurgical residency, during which time he also began work on cancer stem cells in primary brain tumours in the lab of Dr. John Kessler. He was recruited to the University of Toronto in 2010. Dr. Das’s clinical practice and clinical research focus of the treatment of patients with tumours of the brain and spine. His laboratory at the Hospital for SickKids focuses on non-coding RNA and control of cell identity in glioblastoma and neural stem cells. He is a member of the Arthur and Sonia Labatt Brain Tumour Research Centre at the Hospital for Sick Children, and faculty with the Institute of Medical Science and Department of Laboratory Medicine and Pathobiology.

Recent Publications

  1. Kotecha, R, Mehta, MP, Chang, EL, Brown, PD, Suh, JH, Lo, SS et al.. Updates in the management of intradural spinal cord tumors: a radiation oncology focus. Neuro-oncology. 2019; :. doi: 10.1093/neuonc/noz014. PubMed PMID:30977511 .
  2. Woolman, M, Kuzan-Fischer, CM, Ferry, I, Kiyota, T, Luu, B, Wu, M et al.. Picosecond infrared laser desorption mass spectrometry identifies medulloblastoma subgroups on intrasurgical timescales. Cancer Res. 2019; :. doi: 10.1158/0008-5472.CAN-18-3411. PubMed PMID:30890619 .
  3. Wang, S, Ahuja, CS, Das, S. Arachnoiditis Ossificans: a Rare Etiology of Oil-Based Spinal Myelography and Review of Literature. World Neurosurg. 2019; :. doi: 10.1016/j.wneu.2019.02.178. PubMed PMID:30862590 .
  4. Lee, DD, Leão, R, Komosa, M, Gallo, M, Zhang, CH, Lipman, T et al.. DNA hypermethylation within TERT promoter upregulates TERT expression in cancer. J. Clin. Invest. 2019;129 (1):223-229. doi: 10.1172/JCI121303. PubMed PMID:30358567 PubMed Central PMC6307937.
  5. Hafazalla, K, Sahgal, A, Jaja, B, Perry, JR, Das, S. Procarbazine, CCNU and vincristine (PCV) versus temozolomide chemotherapy for patients with low-grade glioma: a systematic review. Oncotarget. 2018;9 (72):33623-33633. doi: 10.18632/oncotarget.25890. PubMed PMID:30263090 PubMed Central PMC6154749.
  6. Das, S. Commentary: A Connectomic Atlas of the Human Cerebrum. Oper Neurosurg (Hagerstown). 2018;15 (suppl_1):S481-S482. doi: 10.1093/ons/opy273. PubMed PMID:30260420 .
  7. McAuliffe, N, Nicholson, S, Rigamonti, A, Hare, GMT, Cusimano, M, Garavaglia, M et al.. Awake craniotomy using dexmedetomidine and scalp blocks: a retrospective cohort study. Can J Anaesth. 2018;65 (10):1129-1137. doi: 10.1007/s12630-018-1178-z. PubMed PMID:29978278 .
  8. Maralani, PJ, Das, S, Mainprize, T, Phan, N, Bharatha, A, Keith, J et al.. Hypoxia Detection in Infiltrative Astrocytoma: Ferumoxytol-based Quantitative BOLD MRI with Intraoperative and Histologic Validation. Radiology. 2018;288 (3):821-829. doi: 10.1148/radiol.2018172601. PubMed PMID:29944077 .
  9. Mansur, A, Hird, MA, Desimone, A, Pshonyak, I, Schweizer, TA, Das, S et al.. Driving habits and behaviors of patients with brain tumors: a self-report, cognitive and driving simulation study. Sci Rep. 2018;8 (1):4635. doi: 10.1038/s41598-018-22937-y. PubMed PMID:29545606 PubMed Central PMC5854700.
  10. Coluccia, D, Figueiredo, CA, Wu, MY, Riemenschneider, AN, Diaz, R, Luck, A et al.. Enhancing glioblastoma treatment using cisplatin-gold-nanoparticle conjugates and targeted delivery with magnetic resonance-guided focused ultrasound. Nanomedicine. 2018;14 (4):1137-1148. doi: 10.1016/j.nano.2018.01.021. PubMed PMID:29471172 .
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Affiliations & Other Activities

  • Assistant Professor, Division of Neurosurgery, Department of Surgery, St. Michael’s Hospital
  • Adjunct Scientist, Brain Tumour Research Centre, Hospital for Sick Children