Sunit Das

MD, PhD, MA, BA

Scientist

Biography

Dr. Sunit Das is a Scientist in the Keenan Research Centre for Biomedical Science and neurosurgeon at St.Michael’s Hospital. He is an Assistant Professor in the Department of Surgery at the University of Toronto. Dr. Das studied English Literature at the University of Michigan and Philosophy at Harvard University before moving to Chicago for medical school at Northwestern University. He completed a Doctor of Philosophy at the National Institutes of Health, where he studied the molecular processes that underly adult neurogenesis in the lab of Dr. ZuHang Sheng. He returned to Chicago for his neurosurgical residency, during which time he also began work on cancer stem cells in primary brain tumours in the lab of Dr. John Kessler. He was recruited to the University of Toronto in 2010. Dr. Das’s clinical practice and clinical research focus of the treatment of patients with tumours of the brain and spine. His laboratory at the Hospital for SickKids focuses on non-coding RNA and control of cell identity in glioblastoma and neural stem cells. He is a member of the Arthur and Sonia Labatt Brain Tumour Research Centre at the Hospital for Sick Children, and faculty with the Institute of Medical Science and Department of Laboratory Medicine and Pathobiology.

Recent Publications

  1. Zeng, KL, Sahgal, A, Husain, ZA, Myrehaug, S, Tseng, CL, Detsky, J et al.. Local control and patterns of failure for "Radioresistant" spinal metastases following stereotactic body radiotherapy compared to a "Radiosensitive" reference. J Neurooncol. 2021; :. doi: 10.1007/s11060-020-03691-6. PubMed PMID:33453002 .
  2. Maralani, PJ, Myrehaug, S, Mehrabian, H, Chan, AKM, Wintermark, M, Heyn, C et al.. Intravoxel incoherent motion (IVIM) modeling of diffusion MRI during chemoradiation predicts therapeutic response in IDH wildtype Glioblastoma. Radiother Oncol. 2021; :. doi: 10.1016/j.radonc.2020.12.037. PubMed PMID:33418005 .
  3. Kuksis, M, Gao, Y, Tran, W, Hoey, C, Kiss, A, Komorowski, AS et al.. The Incidence of Brain Metastases Among Patients with Metastatic Breast Cancer: A Systematic Review and Meta-Analysis. Neuro Oncol. 2020; :. doi: 10.1093/neuonc/noaa285. PubMed PMID:33367836 .
  4. Erickson, AW, Ghodrati, F, Habbous, S, Jerzak, KJ, Sahgal, A, Ahluwalia, MS et al.. HER2-targeted therapy prolongs survival in patients with HER2-positive breast cancer and intracranial metastatic disease: a systematic review and meta-analysis. Neurooncol Adv. ;2 (1):vdaa136. doi: 10.1093/noajnl/vdaa136. PubMed PMID:33305268 PubMed Central PMC7720818.
  5. Ironside, SA, Sahgal, A, Detsky, J, Das, S, Perry, JR. Update on the management of elderly patients with glioblastoma: a narrative review. Ann Palliat Med. 2020; :. doi: 10.21037/apm-20-1206. PubMed PMID:33222472 .
  6. Chan, RW, Chen, H, Myrehaug, S, Atenafu, EG, Stanisz, GJ, Stewart, J et al.. Quantitative CEST and MT at 1.5T for monitoring treatment response in glioblastoma: early and late tumor progression during chemoradiation. J Neurooncol. 2020; :. doi: 10.1007/s11060-020-03661-y. PubMed PMID:33196965 .
  7. Stewart, J, Sahgal, A, Lee, Y, Soliman, H, Tseng, CL, Detsky, J et al.. Quantitating Interfraction Target Dynamics During Concurrent Chemoradiation for Glioblastoma: A Prospective Serial Imaging Study. Int J Radiat Oncol Biol Phys. 2020; :. doi: 10.1016/j.ijrobp.2020.10.002. PubMed PMID:33068687 .
  8. Ong, T, Bharatha, A, Alsufayan, R, Das, S, Lin, AW. MRI predictors for brain invasion in meningiomas. Neuroradiol J. 2020; :1971400920953417. doi: 10.1177/1971400920953417. PubMed PMID:32924772 .
  9. Daigle, P, Mehta, S, Bhayana, R, Das, S, Bharatha, A, Nijhawan, N et al.. Seven-Year Follow-Up of a Patient With a Retained Needlefish Jaw Fragment Abutting Against His Left Internal Carotid Artery. J Neuroophthalmol. 2020; :. doi: 10.1097/WNO.0000000000001060. PubMed PMID:32868564 .
  10. Tseng, CL, Stewart, J, Whitfield, G, Verhoeff, JJC, Bovi, J, Soliman, H et al.. Glioma consensus contouring recommendations from a MR-Linac International Consortium Research Group and evaluation of a CT-MRI and MRI-only workflow. J Neurooncol. 2020;149 (2):305-314. doi: 10.1007/s11060-020-03605-6. PubMed PMID:32860571 PubMed Central PMC7541359.
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Affiliations & Other Activities

  • Assistant Professor, Division of Neurosurgery, Department of Surgery, St. Michael’s Hospital
  • Adjunct Scientist, Brain Tumour Research Centre, Hospital for Sick Children
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