Tom Schweizer

PhD

Director, Neuroscience Research Program

Biography

Dr. Schweizer’s area of interest is in Cognitive Neuroscience and Neuroimaging, focusing on understanding the neural bases for human cognitive and real-world functioning using experimental cognitive paradigms, neuroimaging and neuropsychology. A better understanding of the complex neural systems supporting various cognitive and real-world functions and their breakdown after brain damage (e.g. Stroke, Traumatic Brain Injury, Alzheimer’s Disease) is essential in educating physicians, patients and families and critical in designing effective treatment strategies. Dr. Schweizer and his team have developed a novel and fully immersive driving simulator and touch tablet placed in a 3.0 Tesla functional magnetic resonance imaging (fMRI) system. The MRI compatible equipment can capture brain activity during real world tasks. Dr. Schweizer and his group are also investigating novel approaches to image processing and data analysis in functional neuroimaging, in order to improve the reliability and interpretability of fMRI findings, particularly in clinical and aging populations. Dr. Schweizer is an Ontario Early Researcher Award holder and is supported by a New Investigator Award from the Heart and Stroke Foundation of Canada and research awards from the Ministry of Transportation Ontario and other National peer-reviewed funding agencies including Canadian Institutes for Health Research.

Recent Publications

  1. Talwar, NA, Churchill, NW, Hird, MA, Pshonyak, I, Tam, F, Fischer, CE et al.. The Neural Correlates of the Clock-Drawing Test in Healthy Aging. Front Hum Neurosci. 2019;13 :25. doi: 10.3389/fnhum.2019.00025. PubMed PMID:30804769 PubMed Central PMC6370722.
  2. Fischer, CE, Kortebi, I, Karameh, WK, Kumar, S, Gallagher, D, Golas, A et al.. Examining the Link Between Cardiovascular Risk Factors and Neuropsychiatric Symptoms in Mild Cognitive Impairment and Major Depressive Disorder in Remission. J. Alzheimers Dis. 2019;67 (4):1305-1311. doi: 10.3233/JAD-181099. PubMed PMID:30741676 .
  3. Koo, HKYG, Schweizer, TA, Fischer, CE, Munoz, DG. Abnormal Sleep Behaviours Across the Spectrum of Alzheimer's Disease Severity: Influence of APOE Genotypes and Lewy Bodies. Curr Alzheimer Res. 2019; :. doi: 10.2174/1567205016666190103161034. PubMed PMID:30605058 .
  4. Churchill, NW, Caverzasi, E, Graham, SJ, Hutchison, MG, Schweizer, TA. White matter during concussion recovery: Comparing diffusion tensor imaging (DTI) and neurite orientation dispersion and density imaging (NODDI). Hum Brain Mapp. 2019;40 (6):1908-1918. doi: 10.1002/hbm.24500. PubMed PMID:30585674 .
  5. Karameh, WK, Murari, G, Schweizer, TA, Munoz, DG, Fischer, CE. Psychosis in neurodegenerative disorders: recent developments. Curr Opin Psychiatry. 2019;32 (2):117-122. doi: 10.1097/YCO.0000000000000476. PubMed PMID:30520740 .
  6. Qian, W, Schweizer, TA, Churchill, NW, Millikin, C, Ismail, Z, Smith, EE et al.. Gray Matter Changes Associated With the Development of Delusions in Alzheimer Disease. Am J Geriatr Psychiatry. 2018; :. doi: 10.1016/j.jagp.2018.09.016. PubMed PMID:30503703 .
  7. Churchill, NW, Hutchison, MG, Graham, SJ, Schweizer, TA. Evaluating Cerebrovascular Reactivity during the Early Symptomatic Phase of Sport Concussion. J. Neurotrauma. 2019; :. doi: 10.1089/neu.2018.6024. PubMed PMID:30451069 .
  8. Fornazzari, L, Leggieri, M, Schweizer, TA, Arizaga, RL, Allegri, RF, Fischer, CE et al.. Hyper memory, synaesthesia, savants Luria and Borges revisited. Dement Neuropsychol. ;12 (2):101-104. doi: 10.1590/1980-57642018dn12-020001. PubMed PMID:29988344 PubMed Central PMC6022980.
  9. Di Battista, AP, Churchill, N, Schweizer, TA, Rhind, SG, Richards, D, Baker, AJ et al.. Blood biomarkers are associated with brain function and blood flow following sport concussion. J. Neuroimmunol. 2018;319 :1-8. doi: 10.1016/j.jneuroim.2018.03.002. PubMed PMID:29685283 .
  10. Churchill, NW, Hutchison, MG, Graham, SJ, Schweizer, TA. Connectomic markers of symptom severity in sport-related concussion: Whole-brain analysis of resting-state fMRI. Neuroimage Clin. 2018;18 :518-526. doi: 10.1016/j.nicl.2018.02.011. PubMed PMID:29560308 PubMed Central PMC5857899.
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Affiliations & Other Activities

  • Scientist, Keenan Research Centre for Biomedical Science, St. Michael’s Hospital
  • Associate Professor, Faculty of Medicine (Neurosurgery), University of Toronto
  • Associate Professor, Institute of Biomaterials and Biomedical Engineering (IBBME), University of Toronto
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