Tom Schweizer

PhD

Director, Neuroscience Research Program

Biography

Dr. Schweizer’s area of interest is in Cognitive Neuroscience and Neuroimaging, focusing on understanding the neural bases for human cognitive and real-world functioning using experimental cognitive paradigms, neuroimaging and neuropsychology. A better understanding of the complex neural systems supporting various cognitive and real-world functions and their breakdown after brain damage (e.g. Stroke, Traumatic Brain Injury, Alzheimer’s Disease) is essential in educating physicians, patients and families and critical in designing effective treatment strategies. Dr. Schweizer and his team have developed a novel and fully immersive driving simulator and touch tablet placed in a 3.0 Tesla functional magnetic resonance imaging (fMRI) system. The MRI compatible equipment can capture brain activity during real world tasks. Dr. Schweizer and his group are also investigating novel approaches to image processing and data analysis in functional neuroimaging, in order to improve the reliability and interpretability of fMRI findings, particularly in clinical and aging populations. Dr. Schweizer is an Ontario Early Researcher Award holder and is supported by a New Investigator Award from the Heart and Stroke Foundation of Canada and research awards from the Ministry of Transportation Ontario and other National peer-reviewed funding agencies including Canadian Institutes for Health Research.

Recent Publications

  1. Karimpoor, M, Churchill, NW, Tam, F, Fischer, CE, Schweizer, TA, Graham, SJ et al.. Tablet-Based Functional MRI of the Trail Making Test: Effect of Tablet Interaction Mode. Front Hum Neurosci. 2017;11 :496. doi: 10.3389/fnhum.2017.00496. PubMed PMID:29114212 PubMed Central PMC5660710.
  2. Alotaibi, NM, Wang, JZ, Pasarikovski, CR, Guha, D, Al-Mufti, F, Mamdani, M et al.. Management of raised intracranial pressure in aneurysmal subarachnoid hemorrhage: time for a consensus?. Neurosurg Focus. 2017;43 (5):E13. doi: 10.3171/2017.7.FOCUS17426. PubMed PMID:29088956 .
  3. Fischer, CE, Qian, W, Schweizer, TA, Ismail, Z, Smith, EE, Millikin, CP et al.. Determining the impact of psychosis on rates of false-positive and false-negative diagnosis in Alzheimer's disease. Alzheimers Dement (N Y). 2017;3 (3):385-392. doi: 10.1016/j.trci.2017.06.001. PubMed PMID:29067344 PubMed Central PMC5651446.
  4. Jaja, BNR, Schweizer, TA, Claassen, J, Le Roux, P, Mayer, SA, Macdonald, RL et al.. The SAFARI Score to Assess the Risk of Convulsive Seizure during Admission for Aneurysmal Subarachnoid Hemorrhage. Neurosurgery. 2017; :. doi: 10.1093/neuros/nyx334. PubMed PMID:28973169 .
  5. Churchill, NW, Hutchison, MG, Di Battista, AP, Graham, SJ, Schweizer, TA. Structural, Functional, and Metabolic Brain Markers Differentiate Collision versus Contact and Non-Contact Athletes. Front Neurol. 2017;8 :390. doi: 10.3389/fneur.2017.00390. PubMed PMID:28878729 PubMed Central PMC5572295.
  6. Qian, W, Fischer, CE, Schweizer, TA, Munoz, DG. Association between psychosis phenotype and APOE genotype on the clinical profiles of Alzheimer's disease. Curr Alzheimer Res. 2017; :. doi: 10.2174/1567205014666170829114346. PubMed PMID:28847281 .
  7. Churchill, NW, Hutchison, MG, Richards, D, Leung, G, Graham, SJ, Schweizer, TA et al.. Neuroimaging of sport concussion: persistent alterations in brain structure and function at medical clearance. Sci Rep. 2017;7 (1):8297. doi: 10.1038/s41598-017-07742-3. PubMed PMID:28839132 PubMed Central PMC5571165.
  8. Churchill, NW, Hutchison, MG, Graham, SJ, Schweizer, TA. Symptom correlates of cerebral blood flow following acute concussion. Neuroimage Clin. 2017;16 :234-239. doi: 10.1016/j.nicl.2017.07.019. PubMed PMID:28794982 PubMed Central PMC5545814.
  9. Alotaibi, NM, Ibrahim, GM, Wang, J, Guha, D, Mamdani, M, Schweizer, TA et al.. Neurosurgeon academic impact is associated with clinical outcomes after clipping of ruptured intracranial aneurysms. PLoS ONE. 2017;12 (7):e0181521. doi: 10.1371/journal.pone.0181521. PubMed PMID:28727832 PubMed Central PMC5519166.
  10. Churchill, NW, Caverzasi, E, Graham, SJ, Hutchison, MG, Schweizer, TA. White matter microstructure in athletes with a history of concussion: Comparing diffusion tensor imaging (DTI) and neurite orientation dispersion and density imaging (NODDI). Hum Brain Mapp. 2017;38 (8):4201-4211. doi: 10.1002/hbm.23658. PubMed PMID:28556431 .
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Affiliations & Other Activities

  • Scientist, Keenan Research Centre for Biomedical Science, St. Michael’s Hospital
  • Associate Professor, Faculty of Medicine (Neurosurgery), University of Toronto
  • Associate Professor, Institute of Biomaterials and Biomedical Engineering (IBBME), University of Toronto
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