Dr. Xiao-Yan Wen’s research focuses on incorporation of zebrafish model system and advanced high throughput screening technologies for drug discovery. He recently established the Zebrafish Centre for Advanced Drug Discovery (ZCADD) at St. Michael’s Hospital. With a large infrastructure funding from Canada Foundation for Innovation (CFI), ZCADD houses Canada’s first fully automated zebrafish high- throughput screening platform for zebrafish. In partnership with many academic labs and industrial partners, the Centre has launched over 10 zebrafish-based drug development projects targeting many neurological, cardiovascular, inflammatory diseases, diabetes and cancer.
Dr. Wen received his MD at Jiangxi Medical University in China and PhD at the University of Toronto. He is currently a Staff Scientist in the Keenan Research Centre for Biomedical Science and an Assistant Professor in the Department of Medicine & Physiology at the University of Toronto. He is the founding director of the Zebrafish Centre for Advanced Drug Discovery and the Director for the St. Micahel’s Hospital Zebrafish Core Facility. He is also an Associate Member of the Institute of Medical Science at the University of Toronto and is directing the graduate course module “Animal Models of Human Diseases”.
Dr. Wen organizes the bi-annual (2013, 2015, 2017) Zebrafish for Personalized/Precision Medicine Conference, in addition to other past events such as the 2011 Zebrafish Functional Genomics Workshop, and 2012 Zebrafish Chemical Biology & Pharmacogenomics Workshop.