Clinical Trials Ontario (CTO) is an independent, non-profit organization established with support from the Government of Ontario. Their mandate is to work collaboratively with the clinical trials community, the public, and various partners to attract clinical trial investment to Ontario.
The streamlined ethics review system aims to decrease the time to getting clinical trials started by having ethics review completed by a single, qualified research ethics board performing the review for all sites involved in a study. All other required institutional approvals must also be obtained prior to the conduct of the study at SMH (e.g. Privacy, Clinical Ethics, etc). Each institution’s approval groups may have questions/concerns about the approved Provincial Initial Application (PIA) protocol that a study team will need to direct to the Provincial Lead PI and the Board of Record.
*Note: When St. Michael’s Hospital is the Provincial Applicant site, the research team should immediately create the Centre Initial Application for St. Michael’s Hospital – right after creating the Provincial Initial Application.
Effective September 2020: The Clinical Research Restart application for St. Michael’s Hospital or the Clinical Research Restart application for St. Joseph’s Health Centre will replace the CTO Study Impact Approval form until further notice.
For questions regarding CTO, please contact Elizabeth Huggins Elizabeth.Huggins@unityhealth.to
For questions regarding Clinical Research Restart, please contact Sabrina Aimola Sabrina.Aimola@unityhealth.to
While the online CTO Stream system provides a streamlined approach to research ethics review, researchers at St. Michael’s must ensure that all necessary institutional authorizations and contracts/agreements are in place prior to beginning the research. This information can be found in the SRERS Administration form for St. Michael’s Hospital.
Questions? Please contact Elizabeth Huggins at Elizabeth.Huggins@unityhealth.to or 416-864-6060 x 77689.
If you have technical issues or need help with your submission, contact email@example.com or 1-877-715-2700 (9 am to 5 pm).