Principal or Co-Investigator Change

Please follow these instructions to change the Principal Investigator or Co-Investigator on a study:

Submit completed investigator change package

  1. Complete the change in investigator form in full and obtain PI signature.
    • Include a rationale for the change.
    • Include amended versions all approved documents that are impacted by the change.  One clean and one tracked changes version of all amended documents must be provided.
  2. Submit two (2) full packages in hard copy to the research ethics office, located at 250 Yonge St., 6th floor.

Review of investigator change package by the Research Ethics Board

  1. Investigator changes are reviewed on a first-come, first-served basis.
  2. The contact person for the investigator change will typically be the Research Ethics Coordinator that worked on the original application. If you don’t have a Research Ethics Coordinator, please email
  3. During review of the submission the Research Ethics Coordinator will contact you with any clarifications that are needed prior to approving the change.

Approval of the investigator change application

  1. Once the review is complete and all concerns have been addressed, your investigator change application will be approved.
  2. You will be notified when the approval letter is available for pick up in the research ethics office.