Our Lab Members

Our Principal Investigator

Laurent J. Brochard, MD HDR (PhD equivalent)

Dr. Laurent Brochard is the Keenan Chair in Critical Care and Respiratory Medicine, as well as a scientist in the Critical Care Department of St. Michael’s Hospital.

His research interests include Acute Respiratory Failure, Acute Respiratory Distress Syndrome, Mechanical Ventilation, including Noninvasive Ventilation, Patient-Ventilator Interaction, Extubation and Weaning from Mechanical Ventilation.

Takeshi Yoshida

Post-Doctoral Research Fellow

Dr. Takeshi Yoshida is a graduate from Mie University School of Medicine (MD) in Japan. He completed his clinical training in Osaka and is board certified in Emergency Medicine and Critical Care Medicine – all in the rigorous Japanese system. His graduate research training (PhD) was completed in Osaka (Dr. Fujino) where he demonstrated the convincing laboratory evidence for lung injury resulting from spontaneous effort during mechanical ventilation. He furthered this during a year’s work with Dr. Amato (University of São Paulo) where he described ‘Pendelluft’, a new mechanism of effort-dependent lung injury and developed extensive knowledge on the mechanics of pleural pressures.

He is currently completing an additional 3-year post-doctoral fellowship in Toronto (Dr. Kavanagh/Dr. Brochard) exploring translational research on pleural pressure and its manipulation. Dr. Yoshida has been supported by a RestraComp award from the Hospital for Sick Children. He has won multiple hospital, university and international awards, most recently the ‘Global Rising Star’ award from the Australian and New Zealand Intensive Care Society. He has published 46 papers.

Lu Chen

Post-Doctoral Research Fellow

Dr. Lu Chen graduated from Xiangya Medical School (Hunan, China) in 2004. He completed his specialist training in Intensive Care Medicine, supervised by Dr. Jian-Xin Zhou in Beijing Tiantan Hospital (Beijing, China). He worked with Dr. Marco Ranieri as a visiting scholar in Molinette Hospital (Turin, Italy) for one year since 2010. Afterwards, he returned to China and worked as an intensivist for three years. He currently works at St Michael’s Hospital as a research fellow supervised by Dr. Laurent Brochard, focusing on respiratory physiology and mechanical ventilation, predominantly in patients with acute respiratory distress syndrome.

Tài Olivier Pham

Post-Doctoral Research Fellow

Dr. Tài Pham completed his training in Anesthesia and Intensive Care in Paris. His qualifications include a Master of Public Health, and several University Degrees in the field of Critical Care: Infectious diseases in the ICU; Ultrasonic Techniques in Anesthesia and Intensive Care; Mechanical Ventilation. His main areas of interest comprise observational studies in the ICU, mechanical ventilation, ARDS and he is a member of the executive committee of the LUNG SAFE study recently published in the JAMA. He has worked in the Respiratory Team and the REVA network led by Dr. Brochard in Paris and is also involved in the ECMONet research network.

He is currently both a Research Fellow in Dr. Brochard’s laboratory and a Clinical Fellow in the Medical Surgical ICU of St. Michael’s Hospital.  His main current project is the “INFOVENT” research program which aims at determining the epidemiology of patient-ventilator dyssynchronies in hypoxemic intubated patients and at developing strategies to minimize dyssynchronies and ultimately improve patients outcome.

Irene Telias

Post-Doctoral Research Fellow

Dr. Irene Telias is a MD specialist in Internal Medicine and Critical Care. She was born and raised in Buenos Aires, Argentina. Her research interests are respiratory effort in mechanically ventilated patients and its influence on ventilation induced lung injury and diaphragmatic dysfunction, as well as heart-lung interactions during liberation from mechanical ventilation.

Luis Felipe Damiani

Respiratory Therapist/Clinical Specialist

Luis Felipe Damiani is a physiotherapist who graduated from Universidad Catolica de Valparaiso, Chile in 2010. He holds a Master’s Degree in epidemiology and is now completing his second year as a PhD student at Universidad Catolica de Chile. He holds several diplomas in evidence-based medicine and ventilatory therapy and has a keen research interest in sleep medicine, acute respiratory failure, mechanical ventilation and asynchronies.

Michael Sklar

Clinical/Research Resident

Dr. Michael Sklar completed his Bachelor of Science in Physiology at McGill University and his Doctor of Medicine at the University of Saskatchewan. He is currently completing his residency training in Anesthesia at the University of Toronto. His research interests are respiratory failure and mechanical ventilation.

Orla Smith

Project Manager, Critical Care

My main areas of research interest are decision-making and evidence-based practice in critical care. I am currently conducting a multi-centre study of decision-making preferences and psychological outcomes in family members of critically ill patients funded by Sigma Theta Tau International (STTI). Our research group has recently commenced a program of research to better understand the relationship between homelessness and ICU utilization. I am also currently involved in the development of two national evidence based guidelines related to the prevention and management of ventilator associated pneumonia and the implementation of therapeutic hypothermia post-cardiac arrest.

Thomas Piraino

Respiratory Therapist/Clinical Specialist

Thomas is a Respiratory Therapist and the Clinical Specialist – Mechanical Ventilation for the Centre of Excellence in Mechanical Ventilation (CoEMV).  He has been involved in a number of critical care research studies and has published research, editorials, and textbook chapters related to mechanical ventilation and patient monitoring.

Gyan Sandhu

MSICU Research Coordinator

Frank Bezerra

Post-Doctoral Research Fellow


Frank Bezerra is a Physiotherapist with a PhD from Federal University of Rio de Janeiro, Brazil. He is an Associate Professor within the Department of Biological Sciences at Federal University of Ouro Preto, Minas Gerais, Brazil. In 2013, he completed his first Post-Doctoral from the Laboratory of Respiration Physiology at Carlos Chagas Filho Biophysics Institute, supervised by Prof. Walter Zin. His research interests are surfactant, hyperoxia, oxidative stress, mechanical ventilation and ventilation induced lung injury.

Giulia Cavalot

Rémi Coudroy

Post-Doctoral Research Fellow

Dr. Rémi Coudroy is an Associate Professor in the Medical Intensive Care Unit of Poitiers’ teaching Hospital (France). He completed his MD at the University of Poitiers with a specialty in Internal Medicine and Critical Care Medicine, and is currently PhD student in the INSERM CIC 1402 department at the University of Poitiers. He joined Dr. Brochard’s Research Lab in September 2018 as a Post-Doctoral Research Fellow.

His research interest focuses on the noninvasive management of acute respiratory failure of immunocompromised patients. At St Michael’s Hospital, his main field of research are the physiologic effects of high-flow nasal cannula oxygen therapy, respiratory physiology and airway closure in ARDS.

Fahima Nasreen

Administrative Assistant

Fahima is the administrative assistant to Dr. Laurent Brochard, the Director of the U of T Interdepartmental Division of Critical Care Medicine and Keenan Chair of Critical Care & Respiratory Medicine. She has a varied background in administration, with a little teaching along the way as well. She is overseeing all the administrative functions in the office.

Fahima attained her Bachelor of Arts Degree in English Literature from the National university of Bangladesh. She has completed the Medical office Administration course (Diploma) with honors. She is the friendly voice that will most likely greet you when you call Dr. Brochard’s office! She can be reached at 416-864-5686, or nasreenf@smh.ca