The FIT After Surgery Study is a multicentre cohort study that aims to understand the risks, reasons and impact of new disability after major surgery in people aged 65 years or older. The study aims to include 2000 participants from hospitals across Canada. FIT After Surgery is supported by funding from the Canadian Institutes of Health Research (CIHR) and PSI Foundation.

The POWERS Trial is a substudy of 200 participants within of the FIT After Surgery Study. Each participant wears an activity watch or “Actigraph” for up to 3 months after surgery. The activity watches will describe patients’ physical activity levels and sleeping patterns before and after surgery. This information will help us better understand which patients are more likely to develop problems with recovery after surgery.

Psychologist talking with depressed patient.

This pilot randomized trial of 10 participants will investigate a novel treatment option for individuals with major depression who do not respond to usual antidepressant therapies. The novel treatment is a Stellate Ganglion Block (SGB), which involves injection of local anesthetics into the nerves located in the lower part of the neck.

Patient in hospital breathing through a face mask.

The SMILE Trial is a pilot randomized controlled trial of 40 patients that will investigate another treatment option for major depression: nitrous oxide (commonly known as ‘laughing gas’). Nitrous oxide is an anesthetic agent that is commonly used in dental offices. It causes feelings of relaxation and calmness. The SMILE Pilot Trials aims to evaluate the effect of repeated administrations of nitrous oxide in individuals with major depression who do not respond to usual antidepressant therapies.

Woman’s hand pours the medicine pills out of the bottle

The RECOUP trial is a multicentre randomized study that investigates whether the Transitional Pain Service Program (TPSP) can help patients with chronic pain reduce their need for opioid medications after surgery. The TPSP includes consultations with a pain specialist and psychologist. Patients also use a digital app to help them keep better track of their chronic pain. In total, 210 participants from 6 hospitals will take part in the RECOUP study.

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