C. David Mazer

Research Programs

Critical Illness and Injury Research Centre

Recent Publications

1. McEwen, CC, Amir, T, Qiu, Y, Young, J, Kennedy, K, Grocott, HP et al.. Morbidity and mortality in patients managed with high compared with low blood pressure targets during on-pump cardiac surgery: a systematic review and meta-analysis of randomized controlled trials. Can J Anaesth. 2022; :. doi: 10.1007/s12630-021-02171-3. PubMed PMID:35014001 .
2. Beattie, WS, Lalu, M, Bocock, M, Feng, S, Wijeysundera, DN, Nagele, P et al.. Systematic review and consensus definitions for the Standardized Endpoints in Perioperative Medicine (StEP) initiative: cardiovascular outcomes. Br J Anaesth. 2021;126 (1):56-66. doi: 10.1016/j.bja.2020.09.023. PubMed PMID:33092804 .
3. STARRT-AKI Investigators, Canadian Critical Care Trials Group, Australian and New Zealand Intensive Care Society Clinical Trials Group, United Kingdom Critical Care Research Group, Canadian Nephrology Trials Network, Irish Critical Care Trials Group et al.. Timing of Initiation of Renal-Replacement Therapy in Acute Kidney Injury. N Engl J Med. 2020;383 (3):240-251. doi: 10.1056/NEJMoa2000741. PubMed PMID:32668114 .
4. Shander, A, Brown, J, Licker, M, Mazer, DC, Meier, J, Ozawa, S et al.. Standards and Best Practice for Acute Normovolemic Hemodilution: Evidence-based Consensus Recommendations. J Cardiothorac Vasc Anesth. 2020;34 (7):1755-1760. doi: 10.1053/j.jvca.2020.01.019. PubMed PMID:32127266 .
5. Spence, J, Young, J, Alhazzani, W, Whitlock, R, D'Aragon, F, Um, K et al.. Safety and efficacy of perioperative benzodiazepine administration: study protocol for a systematic review and meta-analysis. BMJ Open. 2019;9 (12):e031895. doi: 10.1136/bmjopen-2019-031895. PubMed PMID:31831540 PubMed Central PMC6924818.
6. Fergusson, DA, Avey, MT, Barron, CC, Bocock, M, Biefer, KE, Boet, S et al.. Reporting preclinical anesthesia study (REPEAT): Evaluating the quality of reporting in the preclinical anesthesiology literature. PLoS One. 2019;14 (5):e0215221. doi: 10.1371/journal.pone.0215221. PubMed PMID:31120888 PubMed Central PMC6532843.
7. Barron, CC, Lalu, MM, Stewart, DJ, Fergusson, D, Yang, H, Moher, D et al.. Assessment of safety and efficacy of mesenchymal stromal cell therapy in preclinical models of acute myocardial infarction: a systematic review protocol. Syst Rev. 2017;6 (1):226. doi: 10.1186/s13643-017-0601-9. PubMed PMID:29116020 PubMed Central PMC5688817.
8. Mehta, RH, Leimberger, JD, van Diepen, S, Meza, J, Wang, A, Jankowich, R et al.. Levosimendan in Patients with Left Ventricular Dysfunction Undergoing Cardiac Surgery. N Engl J Med. 2017;376 (21):2032-2042. doi: 10.1056/NEJMoa1616218. PubMed PMID:28316276 .
9. Deschamps, A, Hall, R, Grocott, H, Mazer, CD, Choi, PT, Turgeon, AF et al.. Cerebral Oximetry Monitoring to Maintain Normal Cerebral Oxygen Saturation during High-risk Cardiac Surgery: A Randomized Controlled Feasibility Trial. Anesthesiology. 2016;124 (4):826-36. doi: 10.1097/ALN.0000000000001029. PubMed PMID:26808629 .
10. Hébert, PC, Fergusson, DA, Hutton, B, Mazer, CD, Fremes, S, Blajchman, M et al.. Regulatory decisions pertaining to aprotinin may be putting patients at risk. CMAJ. 2014;186 (18):1379-86. doi: 10.1503/cmaj.131582. PubMed PMID:25267766 PubMed Central PMC4259771.