Charles de Mestral




Dr. Charles de Mestral is a vascular surgeon at St. Michael’s Hospital and a Surgeon-Scientist in the Department of Surgery of the University of Toronto. He conducts research on clinical effectiveness, as well as the provision, quality and costs of surgical care.  His primary research focus is amputation prevention in people with diabetes and peripheral artery disease. His work is based out of the Li Ka Shing Knowledge Institute of St. Michael’s Hospital and ICES.

Please note: Dr. de Mestral is no longer accepting summer students.


Recent Publications

  1. Gomez, D, Nantais, J, Telesnicki, T, de Mestral, C, Wilton, AS, Stukel, TA et al.. A Population-based Analysis of the COVID-19 Generated Surgical Backlog and Associated Emergency Department Presentations for Inguinal Hernias and Gallstone Disease. Ann Surg. 2022; :. doi: 10.1097/SLA.0000000000005403. PubMed PMID:35081578 .
  2. Muaddi, H, Zhao, X, Leonardelli, GJ, de Mestral, C, Nathens, A, Stukel, TA et al.. Fear of innovation: public's perception of robotic surgery. Surg Endosc. 2022; :. doi: 10.1007/s00464-022-09011-5. PubMed PMID:35059838 .
  3. Li, B, Feridooni, T, Cuen-Ojeda, C, Kishibe, T, de Mestral, C, Mamdani, M et al.. Machine learning in vascular surgery: a systematic review and critical appraisal. NPJ Digit Med. 2022;5 (1):7. doi: 10.1038/s41746-021-00552-y. PubMed PMID:35046493 .
  4. Gordon, L, Soenens, G, Doyen, B, Sunavsky, J, Wheatcroft, M, de Mestral, C et al.. Step, Error, and Event Frameworks in Endovascular Aortic Repair. J Endovasc Ther. 2022; :15266028211068768. doi: 10.1177/15266028211068768. PubMed PMID:35012393 .
  5. de Mestral, C, Gomez, D, Wilton, AS, Lee, DS, Albalawi, Z, Austin, PC et al.. A Population-Based Analysis of Diabetes-Related Care Measures, Foot Complications, and Amputation During the COVID-19 Pandemic in Ontario, Canada. JAMA Netw Open. 2022;5 (1):e2142354. doi: 10.1001/jamanetworkopen.2021.42354. PubMed PMID:34985514 PubMed Central PMC8733837.
  6. Tillmann, BW, Guttman, MP, Nathens, AB, de Mestral, C, Kayssi, A, Haas, B et al.. Author's Reply. J Trauma Acute Care Surg. 2021; :. doi: 10.1097/TA.0000000000003510. PubMed PMID:34936594 .
  7. Erman, A, Ramsay, LC, Sander, B, Haj-Ali, W, Wu, D, Setterfield, M et al.. Impact of COVID-19 on scheduled lower extremity revascularization for chronic limb-threatening ischemia. Br J Surg. 2021;109 (1):e5-e7. doi: 10.1093/bjs/znab404. PubMed PMID:34878108 .
  8. Leung, SN, Al-Omran, M, Greco, E, Hughes, B, Qadura, M, Wheatcroft, M et al.. Harnessing the full potential of hospital-based data to support surgical quality improvement. BMJ Open Qual. 2021;10 (4):. doi: 10.1136/bmjoq-2020-001178. PubMed PMID:34697037 PubMed Central PMC8547498.
  9. An, KR, de Mestral, C, Tam, DY, Qiu, F, Ouzounian, M, Lindsay, TF et al.. Surveillance Imaging Following Acute Type A Aortic Dissection. J Am Coll Cardiol. 2021;78 (19):1863-1871. doi: 10.1016/j.jacc.2021.08.058. PubMed PMID:34696957 .
  10. McAlister, FA, Wang, T, Wang, X, Chu, A, Goodman, SG, van Diepen, S et al.. Statins and SARS-CoV-2 Infection: Results of a Population-Based Prospective Cohort Study of 469 749 Adults From 2 Canadian Provinces. J Am Heart Assoc. 2021;10 (21):e022330. doi: 10.1161/JAHA.121.022330. PubMed PMID:34689613 PubMed Central PMC8751814.
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Affiliations & Other Activities

  • Surgeon, Division of Vascular Surgery, St. Michael’s Hospital
  • Assistant Professor, Department of Surgery, University of Toronto
  • Adjunct Scientist, Institute for Clinical Evaluative Sciences