Charles Kassardjian




Dr. Kassardjian is a neurologist with a clinical focus in the area of peripheral neurological diseases and neurophysiology, with a special interest in genetic myopathies. He is an Assistant Professor at the University of Toronto in the Department of Medicine. His research and educational interests are in the area of quality improvement and patient safety.

A major interest is in the area of medication safety and standardization of practice for neuromuscular patients treated with immunosuppressive medications, including the impact of such medications on the risk of infections and fractures. He is interested in the way that we create and use guidelines in practice, especially when evidence is lacking, such as for patients with rare genetic myopathies. A more recent academic and research focus is in the area of virtual care adoption and optimization among medical specialists, especially as a way to improve access to specialist assessments and testing (e.g. electrophysiological testing).

Along with 2 other colleagues that have an interest in Quality Improvement, Dr. Kassardjian co-founded NQIL (the Neurology Quality and Innovation Lab) as a group to foster city-wide quality and safety projects within the Division of Neurology. An early successful collaboration was the development and publication of the “Virtual Neurologic Examination”, with accompanying videos, as a way to improve clinician proficiency with providing virtual neurological assessments both during and after the pandemic.

Recent Publications

  1. Farahvash, A, Kassardjian, CD, Micieli, JA. Mitochondrial Neurogastrointestinal Encephalopathy Disease: A Rare Disease Diagnosed in Siblings with Double Vision. Case Rep Ophthalmol. ;12 (1):174-181. doi: 10.1159/000514098. PubMed PMID:33976678 PubMed Central PMC8077549.
  2. Muir, RT, Gros, P, Ure, R, Mitchell, SB, Kassardjian, CD, Izenberg, A et al.. Modification to Neurology Residency Training: The Toronto Neurology COVID-19 Pandemic Experience. Neurol Clin Pract. 2021;11 (2):e165-e169. doi: 10.1212/CPJ.0000000000000894. PubMed PMID:33842086 PubMed Central PMC8032416.
  3. Gosse, PJ, Kassardjian, CD, Masellis, M, Mitchell, SB. Virtual care for patients with Alzheimer disease and related dementias during the COVID-19 era and beyond. CMAJ. 2021;193 (11):E371-E377. doi: 10.1503/cmaj.201938. PubMed PMID:33722828 PubMed Central PMC8096398.
  4. Balas, M, Popovic, MM, Kassardjian, CD, Vosoughi, R, Nijhawan, N, Micieli, JA et al.. Limitation of Adduction in a Patient with Multiple Sclerosis Related to Orbital Myositis. Can J Neurol Sci. 2021; :1-2. doi: 10.1017/cjn.2021.18. PubMed PMID:33504399 .
  5. Triplett, JD, Shelly, S, Livne, G, Milone, M, Kassardjian, CD, Liewluck, T et al.. Diagnostic modelling and therapeutic monitoring of immune-mediated necrotizing myopathy: role of electrical myotonia. Brain Commun. 2020;2 (2):fcaa191. doi: 10.1093/braincomms/fcaa191. PubMed PMID:33364599 PubMed Central PMC7749792.
  6. Triplett, J, Kassardjian, CD, Liewluck, T, Tahir, A, Lennon, V, Kopecky, S et al.. Cardiac and Respiratory Complications of Necrotizing Autoimmune Myopathy. Mayo Clin Proc. 2020;95 (10):2144-2149. doi: 10.1016/j.mayocp.2020.03.032. PubMed PMID:32807522 .
  7. Desai, U, Kassardjian, CD, Del Toro, D, Gleveckas-Martens, N, Srinivasan, J, Venesy, D et al.. Guidance for resumption of routine electrodiagnostic testing during the COVID-19 pandemic. Muscle Nerve. 2020;62 (2):176-181. doi: 10.1002/mus.26990. PubMed PMID:32462675 PubMed Central PMC7283872.
  8. Al Hussona, M, Maher, M, Chan, D, Micieli, JA, Jain, JD, Khosravani, H et al.. The Virtual Neurologic Exam: Instructional Videos and Guidance for the COVID-19 Era. Can J Neurol Sci. 2020;47 (5):598-603. doi: 10.1017/cjn.2020.96. PubMed PMID:32434626 PubMed Central PMC7347716.
  9. Gao, MM, Wang, JZ, Liao, J, Reiter, SD, Vyas, MV, Linkewich, E et al.. Delayed Thrombectomy Center Arrival is Associated with Decreased Treatment Probability. Can J Neurol Sci. 2020;47 (6):770-774. doi: 10.1017/cjn.2020.95. PubMed PMID:32418553 .
  10. Kassardjian, CD, Desai, U, Narayanaswami, P, Quality and Patient Safety Committee of the AANEM. Reply: The Optimal Management of Electrodiagnostic Studies during COVID-19 Outbreak. Muscle Nerve. 2020;62 (3):E54. doi: 10.1002/mus.26915. PubMed PMID:32392384 PubMed Central PMC7272989.
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Affiliations & Other Activities

  • Assistant Professor, Division of Neurology, Department of Medicine, University of Toronto
  • Staff Neurologist, Division of Neurology, Department of Medicine, St. Michael’s Hospital
  • Founding Member, Neurology Quality and Innovation Lab (NQIL)