Diana Elizabeth Tullis

MD, FRCPC

Investigator

Biography

As the Director of the Toronto Adult Cystic Fibrosis (CF) Clinic at St. Michael’s Hospital, Dr. Tullis is responsible for the care of 450 adults with CF. Dr. Tullis is a Professor of Medicine at the University of Toronto, the Respirology Division Head at St. Michael’s Hospital, and an Associate Scientist in the Li Ka Shing Knowledge Institute. She is the Cystic Fibrosis Canada Chair in Adult CF Research.

Dr. Tullis has published over 100 articles and book chapters and has lectured nationally and internationally on issues related to CF in adults. She has had 25 years of experience with CF clinical care. She was the Chair of the Clinic Subcommittee of the Medical/Scientific Advisory Board of Cystic Fibrosis Canada from 2005-2011 and in 2010 was a Coach for the Adult Quality Improvement Program run by the American Cystic Fibrosis Foundation.

Recent Publications

  1. Lin, YC, Keenan, K, Gong, J, Panjwani, N, Avolio, J, Lin, F et al.. Cystic fibrosis-related diabetes onset can be predicted using biomarkers measured at birth. Genet Med. 2021; :. doi: 10.1038/s41436-020-01073-x. PubMed PMID:33500570 .
  2. McKone, EF, DiMango, EA, Sutharsan, S, Barto, TL, Campbell, D, Ahluwalia, N et al.. A phase 3, randomized, double-blind, parallel-group study to evaluate tezacaftor/ivacaftor in people with cystic fibrosis heterozygous for F508del-CFTR and a gating mutation. J Cyst Fibros. 2020; :. doi: 10.1016/j.jcf.2020.11.003. PubMed PMID:33339768 .
  3. Gupta, S, Batt, J, Bourbeau, J, Chapman, KR, Gershon, A, Granton, J et al.. Triaging Access to Critical Care Resources in Patients With Chronic Respiratory Diseases in the Event of a Major COVID-19 Surge: Key Highlights From the Canadian Thoracic Society (CTS) Position Statement. Chest. 2020;158 (6):2270-2274. doi: 10.1016/j.chest.2020.07.018. PubMed PMID:32693101 PubMed Central PMC7368654.
  4. Langawi, MA, Byrnes, C, Davies, JC, Hamouda, S, Kabra, M, Rached, SZ et al.. 'Go for it, dream big, work hard and persist': A message to the next generation of CF leaders in recognition of International Women's Day 2020. J Cyst Fibros. 2020;19 (2):184-193. doi: 10.1016/j.jcf.2020.02.021. PubMed PMID:32156627 .
  5. Buonarati, OR, Cook, SG, Goodell, DJ, Chalmers, NE, Rumian, NL, Tullis, JE et al.. CaMKII versus DAPK1 Binding to GluN2B in Ischemic Neuronal Cell Death after Resuscitation from Cardiac Arrest. Cell Rep. 2020;30 (1):1-8.e4. doi: 10.1016/j.celrep.2019.11.076. PubMed PMID:31914378 PubMed Central PMC6959131.
  6. Middleton, PG, Mall, MA, Dřevínek, P, Lands, LC, McKone, EF, Polineni, D et al.. Elexacaftor-Tezacaftor-Ivacaftor for Cystic Fibrosis with a Single Phe508del Allele. N Engl J Med. 2019;381 (19):1809-1819. doi: 10.1056/NEJMoa1908639. PubMed PMID:31697873 PubMed Central PMC7282384.
  7. Heijerman, HGM, McKone, EF, Downey, DG, Van Braeckel, E, Rowe, SM, Tullis, E et al.. Efficacy and safety of the elexacaftor plus tezacaftor plus ivacaftor combination regimen in people with cystic fibrosis homozygous for the F508del mutation: a double-blind, randomised, phase 3 trial. Lancet. 2019;394 (10212):1940-1948. doi: 10.1016/S0140-6736(19)32597-8. PubMed PMID:31679946 PubMed Central PMC7571408.
  8. Mejia, JF, Hirschi, KM, Tsai, KYF, Long, MG, Tullis, BC, Bitter, EEK et al.. Differential placental ceramide levels during gestational diabetes mellitus (GDM). Reprod Biol Endocrinol. 2019;17 (1):81. doi: 10.1186/s12958-019-0523-6. PubMed PMID:31647034 PubMed Central PMC6813062.
  9. Singh, AN, Oehler, J, Torrecilla, I, Kilgas, S, Li, S, Vaz, B et al.. The p97-Ataxin 3 complex regulates homeostasis of the DNA damage response E3 ubiquitin ligase RNF8. EMBO J. 2019;38 (21):e102361. doi: 10.15252/embj.2019102361. PubMed PMID:31613024 PubMed Central PMC6826192.
  10. Bell, SC, Mall, MA, Gutierrez, H, Macek, M, Madge, S, Davies, JC et al.. The future of cystic fibrosis care: a global perspective. Lancet Respir Med. 2020;8 (1):65-124. doi: 10.1016/S2213-2600(19)30337-6. PubMed PMID:31570318 .
Search PubMed

Affiliations & Other Activities

  • Head, Division of Respirology, St. Michael’s Hospital
  • The Cystic Fibrosis Canada Chair in Adult Cystic Fibrosis Research, St. Michael’s Hospital
  • Professor, Department of Medicine, University of Toronto
X