Gerald J. Prud’homme

MD, FRCPC (anatomical pathology)

Scientist, Keenan Research Centre for Biomedical Science


Research Interests

Autoimmune diseases, DNA vaccination, gene therapy, diabetes, tumour immunology

Research Activities

My main research interests are in the areas of autoimmune diseases, tumour immunotherapy and gene therapy. My laboratory has developed a method of non-viral gene transfer that can be utilized for intra-muscular transfer of genes or DNA vaccination. We are currently studying the role of neuropilins in TGF-beta activation, immune regulation and cancer biology. In addition, we are investigating the aryl hydrocarbon receptor as a drug target for the therapy of breast cancer, the inhibition of cancer stem cells, and the prevention of metastatic disease.

Affiliations & Other Activities

  • Clinician-Scientist, Laboratory Medicine, St. Michael’s Hospital
  • Staff Pathologist and Director of the Autopsy Service, Division of Pathology, St. Michael’s Hospital
  • Professor, Laboratory Medicine and Pathobiology, University of Toronto
  • Member, Banting and Best Diabetes Centre, Faculty of Medicine, University of Toronto