Howard Ginsberg

MD, FRCSC, PhD, BASc

Investigator

Biography

Dr. Howard Ginsberg is a graduate from the University of Toronto Neurosurgery Program. He is trained in cranial surgery as well as both neurosurgical and orthopedic spinal surgery techniques. He completed a fellowship in spinal surgery as well as a degree in Engineering Science from the University of Toronto, and a PhD in Biomedical Engineering. He is the Spine Program Director at St. Michael’s Hospital and an Assistant Professor in the Department of Surgery.  Dr. Ginsberg’s research focuses on engineering applications to neurosurgical procedures with the goal of improving safety and outcome for patients. His current research focus is on the development of a rapid tumour diagnostic system that uses mass spectrometry guided laser ablation for molecular analysis to provide a highly precise cancer diagnosis in 10 seconds.

Please note: Dr. Ginsberg is not taking any summer students.

Recent Publications

  1. Voglis, S, Romagna, A, Germans, MR, Carreno, I, Stienen, MN, Henzi, A et al.. Spinal arachnoid web-a distinct entity of focal arachnopathy with favorable long-term outcome after surgical resection. Analysis of a multicenter patient population. Spine J. 2021; :. doi: 10.1016/j.spinee.2021.06.018. PubMed PMID:34175468 .
  2. Woolman, M, Qiu, J, Kuzan-Fischer, CM, Ferry, I, Dara, D, Katz, L et al.. In situ tissue pathology from spatially encoded mass spectrometry classifiers visualized in real time through augmented reality. Chem Sci. 2020;11 (33):8723-8735. doi: 10.1039/d0sc02241a. PubMed PMID:34123126 PubMed Central PMC8163395.
  3. Woolman, M, Katz, L, Gopinath, G, Kiyota, T, Kuzan-Fischer, CM, Ferry, I et al.. Mass Spectrometry Imaging Reveals a Gradient of Cancer-like Metabolic States in the Vicinity of Cancer Not Seen in Morphometric Margins from Microscopy. Anal Chem. 2021;93 (10):4408-4416. doi: 10.1021/acs.analchem.0c04129. PubMed PMID:33651938 .
  4. Nishimura, Y, Hara, M, Natsume, A, Wakabayashi, T, Ginsberg, HJ. Complete resection and untethering of the cervical and thoracic spinal dermal sinus tracts in adult patients. Nagoya J Med Sci. 2020;82 (3):567-577. doi: 10.18999/nagjms.82.3.567. PubMed PMID:33132440 PubMed Central PMC7548243.
  5. Nishimura, Y, Hara, M, Awaya, T, Ando, R, Eguchi, K, Nagashima, Y et al.. Possible Double Crush Syndrome Caused by Iatrogenic Acquired Lumbosacral Epidermoid Tumor and Concomitant Sacral Tarlov Cyst. NMC Case Rep J. 2020;7 (4):195-199. doi: 10.2176/nmccrj.cr.2019-0236. PubMed PMID:33062568 PubMed Central PMC7538451.
  6. Afshar, ME, Abraha, HY, Bakooshli, MA, Davoudi, S, Thavandiran, N, Tung, K et al.. A 96-well culture platform enables longitudinal analyses of engineered human skeletal muscle microtissue strength. Sci Rep. 2020;10 (1):6918. doi: 10.1038/s41598-020-62837-8. PubMed PMID:32332853 PubMed Central PMC7181829.
  7. Wilson, JR, Cronin, S, Fehlings, MG, Kwon, BK, Badhiwala, JH, Ginsberg, HJ et al.. Epidemiology and Impact of Spinal Cord Injury in the Elderly: Results of a Fifteen-Year Population-Based Cohort Study. J Neurotrauma. 2020;37 (15):1740-1751. doi: 10.1089/neu.2020.6985. PubMed PMID:32292120 .
  8. Katz, L, Woolman, M, Talbot, F, Amara-Belgadi, S, Wu, M, Tortorella, S et al.. Dual Laser and Desorption Electrospray Ionization Mass Spectrometry Imaging Using the Same Interface. Anal Chem. 2020;92 (9):6349-6357. doi: 10.1021/acs.analchem.9b05340. PubMed PMID:32275820 .
  9. Guha, D, Jakubovic, R, Leung, MK, Ginsberg, HJ, Fehlings, MG, Mainprize, TG et al.. Quantification of computational geometric congruence in surface-based registration for spinal intra-operative three-dimensional navigation. PLoS One. 2019;14 (8):e0207137. doi: 10.1371/journal.pone.0207137. PubMed PMID:31450234 PubMed Central PMC6710030.
  10. Mithani, K, Meng, Y, Pinilla, D, Thani, N, Tung, K, Leung, R et al.. Diffuse idiopathic skeletal hyperostosis masquerading as asthma: case report. J Neurosurg Spine. 2019; :1-4. doi: 10.3171/2019.2.SPINE181291. PubMed PMID:31026818 .
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Affiliations & Other Activities

  • Assistant Professor, Department of Surgery, University of Toronto
  • Assistant Professor, Department of Surgery, Institute of Biomaterials and Biomedical Engineering, University of Toronto
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