Karen Cross



Research Programs




Dr. Karen Cross is a Plastic and Reconstructive Surgeon and a Surgeon-Entrepreneur at St. Michael’s Hospital. Clinically, Dr. Cross has extensive professional experience in Advanced Tissue Injury Diagnostics and Treatment. She is an Assistant Professor at the University of Toronto and an Adjunct Professor at Ryerson University.  She performs clinical translation research developing non-invasive optical technologies to assess skin physiology. Her research aims are to bring innovative technology from the bench to the bedside. As Co-Founder and CEO of MIMOSA Diagnostics. Dr. Cross is building the next generation of mobile health (mHealth) medical devices, powered by AI and designed to solve some of Health Care’s biggest problems.

Dr. Cross has won several National and International awards related to her research such as the Wound Healing Society Young Investigator Award, Trauma Association of Canada Research Award, and Best Clinical Research from the Canadian Society of Plastic Surgeons. She has been recognized for her excellence as a teacher, her collegiality, generosity, mentorship and humanitarianism by receiving the Dr. Hugh Thompson Humanitarian Award and the Leo Mahoney Teaching Award.

Please note: Dr. Cross is not taking any summer students.

Recent Publications

  1. Klassen, AF, van Haren, ELWG, van Alphen, TC, Cano, S, Cross, KM, van Dishoeck, AM et al.. International study to develop the WOUND-Q patient-reported outcome measure for all types of chronic wounds. Int Wound J. 2021;18 (4):487-509. doi: 10.1111/iwj.13549. PubMed PMID:33694326 PubMed Central PMC8273613.
  2. Squitieri, L, Tsangaris, E, Klassen, AF, van Haren, ELWG, Poulsen, L, Longmire, NM et al.. Patient-reported experience measures are essential to improving quality of care for chronic wounds: An international qualitative study. Int Wound J. 2020;17 (4):1052-1061. doi: 10.1111/iwj.13374. PubMed PMID:32320141 PubMed Central PMC7949344.
  3. Klassen, A, van Haren, EL, Cross, K, Fan, KL, Gibbons, C, Hoogbergen, MM et al.. International mixed methods study protocol to develop a patient-reported outcome measure for all types of chronic wounds (the WOUND-Q). BMJ Open. 2020;10 (3):e032332. doi: 10.1136/bmjopen-2019-032332. PubMed PMID:32217558 PubMed Central PMC7170563.
  4. Hunter, P, Greco, E, Cross, K, Perry, J. Topical Oxygen Therapy Shifts Microbiome Dynamics in Chronic Diabetic Foot Ulcers. Wounds. 2020;32 (3):81-85. . PubMed PMID:32163040 .
  5. Wallace, D, Perry, J, Yu, J, Mehta, J, Hunter, P, Cross, KM et al.. Assessing the Need for Mobile Health (mHealth) in Monitoring the Diabetic Lower Extremity. JMIR Mhealth Uhealth. 2019;7 (4):e11879. doi: 10.2196/11879. PubMed PMID:30990455 PubMed Central PMC6488952.
  6. Leung, G, Duta, D, Perry, J, Leonardi, L, Fish, J, Cross, K et al.. Rapid tissue viability evaluation using methemoglobin as a biomarker in burns. Int J Burns Trauma. 2018;8 (5):126-134. . PubMed PMID:30515351 PubMed Central PMC6261915.
  7. Boodoo, C, Perry, JA, Leung, G, Cross, KM, Isaranuwatchai, W. Cost-effectiveness of telemonitoring screening for diabetic foot ulcer: a mathematical model. CMAJ Open. ;6 (4):E486-E494. doi: 10.9778/cmajo.20180088. PubMed PMID:30337474 PubMed Central PMC6201712.
  8. Roy, M, Perry, JA, Cross, KM. Nutrition and the Plastic Surgeon: Possible Interventions and Practice Considerations. Plast Reconstr Surg Glob Open. 2018;6 (8):e1704. doi: 10.1097/GOX.0000000000001704. PubMed PMID:30324049 PubMed Central PMC6181488.
  9. Boodoo, C, Perry, JA, Hunter, PJ, Duta, DI, Newhook, SCP, Leung, G et al.. Views of Patients on Using mHealth to Monitor and Prevent Diabetic Foot Ulcers: Qualitative Study. JMIR Diabetes. 2017;2 (2):e22. doi: 10.2196/diabetes.8505. PubMed PMID:30291089 PubMed Central PMC6238864.
  10. Chang, YR, Perry, J, Cross, K. Low-Frequency Ultrasound Debridement in Chronic Wound Healing: A Systematic Review of Current Evidence. Plast Surg (Oakv). 2017;25 (1):21-26. doi: 10.1177/2292550317693813. PubMed PMID:29026808 PubMed Central PMC5626185.
Search PubMed

Affiliations & Other Activities

  • Assistant Professor, Department of Surgery, University of Toronto
  • Adjunct Professor, Ryerson Unversity