Samir Gupta



Research Programs


Samir Gupta is a Respirologist and clinician-scientist at the Li Ka Shing Knowledge Institute of St. Michael’s Hospital and an Associate Professor in the Department of Medicine at the University of Toronto.  He completed his Master’s degree in Clinical Epidemiology at the University of Toronto, followed by a fellowship in Knowledge Translation Research.

His main research interest is in knowledge translation across the spectrum of respiratory illness, with a focus on electronic tools for behaviour change. His team built and launched the Electronic Asthma Management System (eAMS) ( He also has an interest in rare lung disease research methods, and is founder and Head of the Canadian Hepatopulmonary Syndrome Program ( He has a specific interest in science communication, and serves as a medical correspondent for various media outlets.  He also serves as Chair of the Canadian Respiratory Guidelines Committee and holds the University of Toronto Michael Locke Term Chair in Knowledge Translation and Rare Lung Disease Research.

Recent Publications

  1. Gupta, S, Panchal, P, Sadatsafavi, M, Ghanouni, P, Sin, D, Pakhale, S et al.. A personalized biomedical risk assessment infographic for people who smoke with COPD: a qualitative study. Addict Sci Clin Pract. 2022;17 (1):1. doi: 10.1186/s13722-021-00283-1. PubMed PMID:34991699 PubMed Central PMC8734321.
  2. Mullins, N, Kang, J, Campos, AI, Coleman, JRI, Edwards, AC, Galfalvy, H et al.. Dissecting the Shared Genetic Architecture of Suicide Attempt, Psychiatric Disorders, and Known Risk Factors. Biol Psychiatry. 2022;91 (3):313-327. doi: 10.1016/j.biopsych.2021.05.029. PubMed PMID:34861974 .
  3. Yamada, J, Cheung, JLS, Gagne, M, Spiegel-Feld, C, Aaron, SD, FitzGerald, JM et al.. Barriers and Enablers to Objective Testing for Asthma and COPD in Primary Care: A Systematic Review Using the Theoretical Domains Framework. Chest. 2021; :. doi: 10.1016/j.chest.2021.10.030. PubMed PMID:34740591 .
  4. Parikh, H, Lui, E, Faughnan, ME, Al-Hesayen, A, Segovia, S, Gupta, S et al.. Supine vs upright exercise in patients with hepatopulmonary syndrome and orthodeoxia: study protocol for a randomized controlled crossover trial. Trials. 2021;22 (1):683. doi: 10.1186/s13063-021-05633-7. PubMed PMID:34625098 PubMed Central PMC8500814.
  5. Gagné, M, Lam Shin Cheung, J, Kouri, A, FitzGerald, JM, O'Byrne, PM, Boulet, LP et al.. A patient decision aid for mild asthma: Navigating a new asthma treatment paradigm. Respir Med. 2021; :106568. doi: 10.1016/j.rmed.2021.106568. PubMed PMID:34429221 .
  6. Stojanovic, J, Boucher, VG, Gagne, M, Gupta, S, Joyal-Desmarais, K, Paduano, S et al.. Global Trends and Correlates of COVID-19 Vaccination Hesitancy: Findings from the iCARE Study. Vaccines (Basel). 2021;9 (6):. doi: 10.3390/vaccines9060661. PubMed PMID:34204379 PubMed Central PMC8235754.
  7. Gupta, S, Tang, R, Al-Hesayen, A. Inhaled nitric oxide improves the hepatopulmonary syndrome: a physiologic analysis. Thorax. 2021;76 (11):1142-1145. doi: 10.1136/thoraxjnl-2020-216128. PubMed PMID:33859047 .
  8. Yamada, J, Kouri, A, Simard, SN, Segovia, SA, Gupta, S. Barriers and Enablers to Using a Patient-Facing Electronic Questionnaire: A Qualitative Theoretical Domains Framework Analysis. J Med Internet Res. 2020;22 (10):e19474. doi: 10.2196/19474. PubMed PMID:33030437 PubMed Central PMC7582145.
  9. To, T, Lougheed, MD, McGihon, R, Zhu, J, Gupta, S, Licskai, C et al.. Does an mHealth system reduce health service use for asthma?. ERJ Open Res. 2020;6 (3):. doi: 10.1183/23120541.00340-2019. PubMed PMID:32963990 PubMed Central PMC7487344.
  10. Kouri, A, Yamada, J, Sale, JEM, Straus, SE, Gupta, S. Primary Care Pre-Visit Electronic Patient Questionnaire for Asthma: Uptake Analysis and Predictor Modeling. J Med Internet Res. 2020;22 (9):e19358. doi: 10.2196/19358. PubMed PMID:32945779 PubMed Central PMC7532461.
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Affiliations & Other Activities

  • Staff Respirologist, Division of Respirology, St. Michael’s Hospital
  • Michael Locke Chair in Knowledge Translation and Rare Lung Diseases, St. Michael’s Hospital
  • Associate Professor, Department of Medicine, Division of Respirology, University of Toronto
  • Chair, Canadian Respiratory Guidelines Committee