Sharon Straus



Research Programs


Sharon E. Straus is a geriatrician and clinical epidemiologist who trained at the University of Toronto and the University of Oxford.  She is the Director of the Knowledge Translation Program and Physician-in-Chief, St. Michael’s Hospital and Professor in Department of Medicine, University of Toronto.  She holds a Tier 1 Canada Research Chair in Knowledge Translation and Quality of Care and has authored more than 500 peer-reviewed publications and 3 textbooks in evidence-based medicine, knowledge translation and mentorship.  Since 2015, she has consistently been in the top 1% of highly cited clinical researchers as per Web of Science and has an H-index of 103. She has held more than $60 million in peer-reviewed research grants as a principal investigator.  She has received national awards for mentorship, research and education.


Recent Publications

  1. Wong, EKC, Watt, J, Zou, H, Chandraraj, A, Zhang, AW, Norman, R et al.. Mortality in hospitalized older adults with COVID-19 during three waves: A multicenter retrospective cohort study. Health Sci Rep. 2022;5 (3):e603. doi: 10.1002/hsr2.603. PubMed PMID:35509386 PubMed Central PMC9059224.
  2. Veroniki, AA, Ashoor, HM, Rios, P, Seitidis, G, Stewart, L, Clarke, M et al.. Comparative safety and efficacy of cognitive enhancers for Alzheimer's dementia: a systematic review with individual patient data network meta-analysis. BMJ Open. 2022;12 (4):e053012. doi: 10.1136/bmjopen-2021-053012. PubMed PMID:35473731 PubMed Central PMC9045061.
  3. Sheikh-Mohamed, S, Isho, B, Chao, GYC, Zuo, M, Cohen, C, Lustig, Y et al.. Systemic and mucosal IgA responses are variably induced in response to SARS-CoV-2 mRNA vaccination and are associated with protection against subsequent infection. Mucosal Immunol. 2022; :. doi: 10.1038/s41385-022-00511-0. PubMed PMID:35468942 PubMed Central PMC9037584.
  4. Banerjee, A, Lew, J, Kroeker, A, Baid, K, Aftanas, P, Nirmalarajah, K et al.. Immunogenicity of convalescent and vaccinated sera against clinical isolates of ancestral SARS-CoV-2, beta, delta, and omicron variants. Med (N Y). 2022; :. doi: 10.1016/j.medj.2022.04.002. PubMed PMID:35437520 PubMed Central PMC9008123.
  5. Donald, M, Beanlands, H, Straus, S, Harwood, L, Herrington, G, Waldvogel, B et al.. A Research Protocol for Implementation and Evaluation of a Patient-Focused eHealth Intervention for Chronic Kidney Disease. Glob Implement Res Appl. 2022;2 (1):85-94. doi: 10.1007/s43477-022-00038-3. PubMed PMID:35402999 PubMed Central PMC8938369.
  6. Leigh, JP, Sypes, EE, Straus, SE, Demiantschuk, D, Ma, H, Brundin-Mather, R et al.. Determinants of the de-implementation of low-value care: a multi-method study. BMC Health Serv Res. 2022;22 (1):450. doi: 10.1186/s12913-022-07827-4. PubMed PMID:35387673 PubMed Central PMC8985316.
  7. Saunders, H, Pham, B, Loong, D, Mishra, S, Ashoor, HM, Antony, J et al.. The Cost-Effectiveness Of Intermediate-Acting, Long-Acting, Ultralong-Acting, and Biosimilar Insulins for Type 1 Diabetes Mellitus: A Systematic Review. Value Health. 2022; :. doi: 10.1016/j.jval.2021.12.016. PubMed PMID:35341688 .
  8. Amog, K, Pham, B, Courvoisier, M, Mak, M, Booth, A, Godfrey, C et al.. The web-based "Right Review" tool asks reviewers simple questions to suggest methods from 41 knowledge synthesis methods. J Clin Epidemiol. 2022;147 :42-51. doi: 10.1016/j.jclinepi.2022.03.004. PubMed PMID:35314349 .
  9. Tricco, AC, Thomas, SM, Radhakrishnan, A, Ramkissoon, N, Mitchell, G, Fortune, J et al.. Interventions for social isolation in older adults who have experienced a fall: a systematic review. BMJ Open. 2022;12 (3):e056540. doi: 10.1136/bmjopen-2021-056540. PubMed PMID:35264363 PubMed Central PMC8915346.
  10. Verma, AA, Murray, J, Greiner, R, Cohen, JP, Shojania, KG, Ghassemi, M et al.. Implementing machine learning in medicine. CMAJ. 2021;193 (34):E1351-E1357. doi: 10.1503/cmaj.202434. PubMed PMID:35213323 PubMed Central PMC8432320.
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Affiliations & Other Activities

  • Scientist, Li Ka Shing Knowledge Institute, St. Michael’s Hospital
  • Physician-in-Chief, St. Michael’s Hospital
  • Professor, Department of Medicine, University of Toronto
  • Professor (status only), Department of Health Policy Management and Evaluation, University of Toronto
  • Principal Investigator, Knowledge Translation Program, University of Toronto
  • Professor, Department of Medicine, University of Calgary