Ziv Harel

MD, MSc

Investigator

Biography

Ziv Harel is a nephrologist and Assistant Professor of Medicine at the University of Toronto. He completed his undergraduate degrees at the University of Toronto, medical school at the University of Western Ontario, and continued his clinical training in internal medicine and nephrology at the University of Toronto. Following this, he completed a Master’s degree in Clinical Epidemiology at the University of Toronto, a research fellowship at Women’s College Hospital, and the Veteran’s Health Administration Quality Scholars (VAQS) Fellowship in patient safety. In addition to attending on the hospital’s Nephrology consult and ward services, Dr. Harel provides longitudinal care for patients on chronic hemodialysis and has an active general nephrology practice.

Dr. Harel’s research interests are in the areas of anticoagulation in patients receiving dialysis, the interplay of pregnancy and the kidney, and patient safety in individuals with chronic kidney disease. He is currently leading a Canadian Institutes of Health Research-funded international trial on the role of oral anticoagulation in patients with atrial fibrillation receiving chronic dialysis. As a founding member of the Kidney Dialysis and Transplantation Program at ICES, Dr. Harel is also involved in several studies that are using province-wide population-based data to answer research questions in kidney disease.

Recent Publications

  1. Kitchlu, A, Jhaveri, KD, Wadhwani, S, Deshpande, P, Harel, Z, Kishibe, T et al.. A Systematic Review of Immune Checkpoint Inhibitor-Associated Glomerular Disease. Kidney Int Rep. 2021;6 (1):66-77. doi: 10.1016/j.ekir.2020.10.002. PubMed PMID:33426386 PubMed Central PMC7783581.
  2. Davidson, AJF, Park, AL, Berger, H, Aoyama, K, Harel, Z, Cohen, E et al.. Association of Improved Periconception Hemoglobin A1c With Pregnancy Outcomes in Women With Diabetes. JAMA Netw Open. 2020;3 (12):e2030207. doi: 10.1001/jamanetworkopen.2020.30207. PubMed PMID:33355674 PubMed Central PMC7758806.
  3. Silver, SA, Beaubien-Souligny, W, Shah, PS, Harel, S, Blum, D, Kishibe, T et al.. The Prevalence of Acute Kidney Injury in Patients Hospitalized With COVID-19 Infection: A Systematic Review and Meta-analysis. Kidney Med. ;3 (1):83-98.e1. doi: 10.1016/j.xkme.2020.11.008. PubMed PMID:33319190 PubMed Central PMC7723763.
  4. Blum, D, Meraz-Munoz, A, Harel, Z. Kidney injury associated with COVID-19. CMAJ. 2020;192 (37):E1065. doi: 10.1503/cmaj.201553. PubMed PMID:32928802 PubMed Central PMC7513941.
  5. Rej, S, Herrmann, N, Gruneir, A, McArthur, E, Jeyakumar, N, Muanda, FT et al.. Association of Lithium Use and a Higher Serum Concentration of Lithium With the Risk of Declining Renal Function in Older Adults: A Population-Based Cohort Study. J Clin Psychiatry. 2020;81 (5):. doi: 10.4088/JCP.19m13045. PubMed PMID:32841553 .
  6. Harel, Z, Park, AL, McArthur, E, Hladunewich, M, Dirk, JS, Wald, R et al.. Prepregnancy renal function and risk of preterm birth and related outcomes. CMAJ. 2020;192 (30):E851-E857. doi: 10.1503/cmaj.200089. PubMed PMID:32719020 PubMed Central PMC7828914.
  7. Hill, K, Sucha, E, Rhodes, E, Carrier, M, Garg, AX, Harel, Z et al.. Risk of Hospitalization With Hemorrhage Among Older Adults Taking Clarithromycin vs Azithromycin and Direct Oral Anticoagulants. JAMA Intern Med. 2020;180 (8):1052-1060. doi: 10.1001/jamainternmed.2020.1835. PubMed PMID:32511684 PubMed Central PMC7281381.
  8. Davidson, AJF, Park, AL, Berger, H, Aoyama, K, Harel, Z, Cook, JL et al.. Risk of severe maternal morbidity or death in relation to elevated hemoglobin A1c preconception, and in early pregnancy: A population-based cohort study. PLoS Med. 2020;17 (5):e1003104. doi: 10.1371/journal.pmed.1003104. PubMed PMID:32427997 PubMed Central PMC7236974.
  9. Somaili, M, Jeyakumar, N, McArthur, E, Ribic, C, Sood, MM, Harel, Z et al.. Incidence of Direct Oral Anticoagulant Prescriptions in Kidney Transplant Recipients in Ontario, Canada. Transplant Proc. 2020;52 (10):3144-3152. doi: 10.1016/j.transproceed.2020.02.171. PubMed PMID:32402459 .
  10. Iskander, C, Cherney, DZ, Clemens, KK, Dixon, SN, Harel, Z, Jeyakumar, N et al.. Use of sodium-glucose cotransporter-2 inhibitors and risk of acute kidney injury in older adults with diabetes: a population-based cohort study. CMAJ. 2020;192 (14):E351-E360. doi: 10.1503/cmaj.191283. PubMed PMID:32392523 PubMed Central PMC7145366.
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Affiliations & Other Activities

  • Adjunct Scientist, ICES
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